Article
Endocrinology & Metabolism
Jinqian Mao, Jin Hu, Yanting Zhang, Jian Shen, Fang Dong, Ximeng Zhang, Jie Ming, Tao Huang, Xiaoqin Run
Summary: This study compared single hormone receptor-positive breast cancer to other subtypes and found clinically and biologically distinct features. The prognosis of single hormone receptor-positive tumors was similar to hormone receptor-negative and hormone receptor-positive tumors in patients with or without HER2 overexpression.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Oncology
Min Xiao, Pin Zhang
Summary: This study evaluated the conditional cause-specific survival of breast cancer patients after chemotherapy and local treatment for metastases, and identified prognostic factors affecting this survival. The results showed an increase in survival rate as the years of survival increased. HER2 status, multisite metastasis, and local treatment were identified as independent prognostic factors for long-term survival.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Lin Liu, Jinglan Zhu, Yun Tian
Summary: Bladder carcinosarcoma (BCS) has been found to have distinct clinicopathologic characteristics and prognosis compared to conventional bladder cancer histologies. BCS is associated with poor differentiation, advanced stage, and worse overall survival and cancer-specific survival. However, BCS is comparable to squamous cell carcinoma (SCC) in terms of survival. These findings contribute to a better understanding of BCS and have potential implications for clinical practice.
Article
Oncology
Caihong Zheng, Chengbin Fu, Yahui Wen, Jiameng Liu, Shunguo Lin, Hui Han, Zhonghua Han, Chunsen Xu
Summary: A nomogram was developed and validated to predict the overall survival of patients with metaplastic breast cancer (MBC). MBC patients had worse clinical prognosis compared to infiltrating ductal carcinoma. This nomogram can assist clinicians in making more accurate individualized survival analyses.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Mingkun Zhang, Yuan Qin, Niuniu Hou, Fuqing Ji, Zhihao Zhang, Juliang Zhang
Summary: This study aimed to establish a nomogram for accurately predicting the overall survival (OS) of patients with non-metastatic invasive micropapillary breast carcinoma (IMPC). Data from 429 patients in the Surveillance, Epidemiology, and End Results (SEER) database were analyzed to establish a nomogram for predicting OS at 3, 5, and 8 years. The nomogram showed good calibration and predictive accuracy in both the training and validation cohorts, and could help optimize treatment strategies based on individual risk factors.
FRONTIERS IN ONCOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Fangxu Yin, Song Wang, Chong Hou, Yiyuan Zhang, Zhenlin Yang, Xiaohong Wang
Summary: This study developed two accurate prediction models for survival outcomes in locally advanced breast cancer patients, which were more accurate than conventional TNM staging. These models can guide clinical decision-making and treatment planning for these patients.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Surgery
Lingyu Han, Weixing Dai, Shaobo Mo, Wenqiang Xiang, Qingguo Li, Ye Xu, Guoxiang Cai, Renjie Wang
Summary: The study found that patients with metastatic colorectal cancer demonstrated a substantial increase in conditional survival over time. Factors affecting survival may change gradually, and nomograms based on survival time can accurately predict survival for patients with mCRC.
INTERNATIONAL JOURNAL OF SURGERY
(2021)
Article
Oncology
Yuan Zhou, Changming Lin, Lian Zhu, Rentao Zhang, Lei Cheng, Yuanyuan Chang
Summary: This study established predictive models and a scoring system to predict the survival rate of prostate cancer patients. These tools can help clinicians individually assess the survival status of patients and contribute to clinical decisions.
Article
Medicine, General & Internal
Jingkun Qu, Chaofan Li, Mengjie Liu, Yusheng Wang, Zeyao Feng, Jia Li, Weiwei Wang, Fei Wu, Shuqun Zhang, Xixi Zhao
Summary: This study analyzed the clinical features and prognostic factors of occult breast cancer (OBC) patients and constructed machine learning prognostic models with high precision and applicability to predict overall survival. The results showed that surgery and radiotherapy had a protective effect on OBC patients, while chemotherapy was only effective in certain molecular subtypes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Jing Wang, Xiang-zhi Ni, Ming-lei Yang, Xing Huang, Shu-ming Hou, Cheng Peng, Jia-shi Cao, Tie-Long Liu
Summary: This study comprehensively analyzed the demographic features, clinicopathologic characteristics and prognosis factors of spinal osteosarcoma using the SEER database. The results showed that male gender, high tumor grade, regional and metastasis stage, as well as radiotherapy, were independent predictors of poor survival in spinal osteosarcoma patients. The clinical treatment of spinal osteosarcoma still faces serious challenges.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Taiwo Adesoye, Oluwatowo Babayemi, Lauren M. Postlewait, Sarah M. DeSnyder, Susie X. Sun, Wendy A. Woodward, Naoto T. Ueno, Kelly K. Hunt, Anthony Lucci, Mediget Teshome
Summary: This study evaluated the age-related differences in patients with inflammatory breast cancer (IBC) and found no significant disparities in demographics, treatment patterns, or clinical outcomes between patients aged 40 years or younger and those aged 65 years or older. These findings do not support age-related treatment de-escalation in IBC.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Medicine, General & Internal
Bing Chen, Xiaojuan Zhang, Yi Liu, Chuandong Wang
Summary: This study compared the clinical characteristics of young TNBC patients with young non-TNBC patients and found that young TNBC patients have higher pathological stage and worse long-term survival. These findings are important for identifying and treating young TNBC patients, and further research on new multimodal treatments is warranted.
Article
Oncology
Jin Hu, Huiqiong Zhang, Fang Dong, Ximeng Zhang, Shuntao Wang, Jie Ming, Tao Huang
Summary: This study found that molecular subtype of breast cancer is not associated with prognosis, and patients can benefit from radiotherapy. However, after receiving radiotherapy, triple-negative patients had superior survival compared to HR-positive or HER2-positive patients.
TRANSLATIONAL ONCOLOGY
(2021)
Article
Medicine, General & Internal
Peng Wen, Jiao Wen, Xiaolong Huang, Fengze Wang
Summary: This study successfully constructed two nomogram models to predict overall survival (OS) and cancer-specific survival (CSS) of bladder cancer patients, which have clinical significance.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Lan An, Wen Ju, Rongshou Zheng, Hongmei Zeng, Siwei Zhang, Ru Chen, Kexin Sun, Li Li, Shaoming Wang, Wenqiang Wei
Summary: The survival rate for elderly cancer patients in the United States has slightly improved from 1995 to 2014, potentially due to advancements in treatment. Except for patients aged 85 and above, the cancer survival rate has improved for elderly patients in all age groups. For all types of cancer, the relative survival rate for localized stage improved from 84.7% to 86.7% and for distant stage improved from 12.4% to 18.7% comparing 1995-1999 with 2010-2014. The trends in stage distribution and treatment rate for all cancers combined remained relatively stable.
