Progress of co-culture systems in cartilage regeneration

Hypoxia Is a Critical Parameter for Chondrogenic Differentiation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Type I/III Collagen Sponges

(2017) Tangni Gómez-Leduc et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of Various Ratios of Co-Cultured ATDC5 Cells and Chondrocytes on the Expression of Cartilaginous Phenotype in Microcavitary Alginate Hydrogel

(2017) Yongchang Yao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Self-patterning of adipose-derived mesenchymal stem cells and chondrocytes cocultured on hyaluronan-grafted chitosan surface

(2016) Hsi-Yi Yeh et al.   Biointerphases

Immunomodulatory effects of mesenchymal stromal cells-derived exosome

(2016) Wancheng Chen et al.   IMMUNOLOGIC RESEARCH

Chondrogenesis by bone marrow-derived mesenchymal stem cells grown in chondrocyte-conditioned medium for auricular reconstruction

(2016) Xing Zhao et al.   Journal of Tissue Engineering and Regenerative Medicine

Nasal chondrocyte-based engineered autologous cartilage tissue for repair of articular cartilage defects: an observational first-in-human trial

(2016) Marcus Mumme et al.   LANCET

Self-patterning of adipose-derived mesenchymal stem cells and chondrocytes cocultured on hyaluronan-grafted chitosan surface

(2016) Hsi-Yi Yeh et al.   Biointerphases

Modulating stem cell–chondrocyte interactions for cartilage repair using combinatorial extracellular matrix-containing hydrogels

(2016) Tianyi Wang et al.   Journal of Materials Chemistry B

In vitro chondrogenic commitment of human Wharton's jelly stem cells by co-culture with human articular chondrocytes

(2015) R. C. Pereira et al.   Journal of Tissue Engineering and Regenerative Medicine

Direct Cell–Cell Contact with Chondrocytes Is a Key Mechanism in Multipotent Mesenchymal Stromal Cell-Mediated Chondrogenesis

(2015) Tommy S. de Windt et al.   TISSUE ENGINEERING PART A

Regeneration of human-ear-shaped cartilage by co-culturing human microtia chondrocytes with BMSCs

(2014) Lu Zhang et al.   BIOMATERIALS

Articular chondrocytes and mesenchymal stem cells seeded on biodegradable scaffolds for the repair of cartilage in a rat osteochondral defect model

(2014) Rebecca L. Dahlin et al.   BIOMATERIALS

Different Ratios of Bone Marrow Mesenchymal Stem Cells and Chondrocytes Used in Tissue-Engineered Cartilage and Its Application for Human Ear-Shaped Substitutes in vitro

(2014) Ning Kang et al.   CELLS TISSUES ORGANS

Chondrogenic Phenotype of Articular Chondrocytes in Monoculture and Co-Culture with Mesenchymal Stem Cells in Flow Perfusion

(2014) Rebecca L. Dahlin et al.   TISSUE ENGINEERING PART A

Articular Chondrocyte Redifferentiation in 3D Co-cultures with Mesenchymal Stem Cells

(2014) Ville V. Meretoja et al.   TISSUE ENGINEERING PART C-METHODS

Single-Stage Cell-Based Cartilage Regeneration Using a Combination of Chondrons and Mesenchymal Stromal Cells

(2013) Joris E.J. Bekkers et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Articular chondrocyte network mediated by gap junctions: role in metabolic cartilage homeostasis

(2013) Maria D Mayan et al.   ANNALS OF THE RHEUMATIC DISEASES

The effect of hypoxia on the chondrogenic differentiation of co-cultured articular chondrocytes and mesenchymal stem cells in scaffolds

(2013) Ville V. Meretoja et al.   BIOMATERIALS

TGF-β3-induced chondrogenesis in co-cultures of chondrocytes and mesenchymal stem cells on biodegradable scaffolds

(2013) Rebecca L. Dahlin et al.   BIOMATERIALS

In vivo screening of extracellular matrix components produced under multiple experimental conditions implanted in one animal

(2013) Gustavo A. Higuera et al.   Integrative Biology

Co-cultivated mesenchymal stem cells support chondrocytic differentiation of articular chondrocytes

(2013) Qiang Zuo et al.   INTERNATIONAL ORTHOPAEDICS

In vitro generation of whole osteochondral constructs using rabbit bone marrow stromal cells, employing a two-chambered co-culture well design

(2013) Kelei Chen et al.   Journal of Tissue Engineering and Regenerative Medicine

In vitroandin vivoco-culture of chondrocytes and bone marrow stem cells in photocrosslinked PCL-PEG-PCL hydrogels enhances cartilage formation

(2013) Chao-Yin Ko et al.   Journal of Tissue Engineering and Regenerative Medicine

Chondrogenic differentiation of human umbilical cord blood-derived mesenchymal stem cells by co-culture with rabbit chondrocytes

(2013) PENGFEI ZHENG et al.   Molecular Medicine Reports

Basic science and clinical application of platelet-rich plasma for cartilage defects and osteoarthritis: a review

(2013) Y. Zhu et al.   OSTEOARTHRITIS AND CARTILAGE

Mesenchymal Stem Cells Downregulate Articular Chondrocyte Differentiation in Noncontact Coculture Systems: Implications in Cartilage Tissue Regeneration

(2013) Lei Xu et al.   STEM CELLS AND DEVELOPMENT

Fibroblast Growth Factor-1 Is a Mesenchymal Stromal Cell-Secreted Factor Stimulating Proliferation of Osteoarthritic Chondrocytes in Co-Culture

(2013) Ling Wu et al.   STEM CELLS AND DEVELOPMENT

Enhanced chondrogenesis in co-cultures with articular chondrocytes and mesenchymal stem cells

(2012) Ville V. Meretoja et al.   BIOMATERIALS

Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering

(2012) Elise Duval et al.   BIOMATERIALS

Chondrogenesis by Co-culture of Adipose-Derived Stromal Cells and Chondrocytes In Vitro

(2012) Xiaojie Lv et al.   CONNECTIVE TISSUE RESEARCH

Cartilage graft engineering by co-culturing primary human articular chondrocytes with human bone marrow stromal cells

(2012) Maria Antonietta Sabatino et al.   Journal of Tissue Engineering and Regenerative Medicine

A mixed co-culture of mesenchymal stem cells and transgenic chondrocytes in alginate hydrogel for cartilage tissue engineering

(2012) Feng Zhang et al.   Journal of Tissue Engineering and Regenerative Medicine

Mesenchymal stem cells secrete factors that inhibit inflammatory processes in short-term osteoarthritic synovium and cartilage explant culture

(2012) G.M. van Buul et al.   OSTEOARTHRITIS AND CARTILAGE

Hypoxia Impedes Hypertrophic Chondrogenesis of Human Multipotent Stromal Cells

(2012) Debby Gawlitta et al.   TISSUE ENGINEERING PART A

Trophic Effects of Mesenchymal Stem Cells in Chondrocyte Co-Cultures are Independent of Culture Conditions and Cell Sources

(2012) Ling Wu et al.   TISSUE ENGINEERING PART A

Coculture of Engineered Cartilage With Primary Chondrocytes Induces Expedited Growth

(2011) Andrea R. Tan et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Enhanced chondrocyte proliferation and mesenchymal stromal cells chondrogenesis in coculture pellets mediate improved cartilage formation

(2011) Chitrangada Acharya et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy

(2011) M.E. Cooke et al.   OSTEOARTHRITIS AND CARTILAGE

Chondrogenic Priming Adipose-Mesenchymal Stem Cells for Cartilage Tissue Regeneration

(2011) Nathaniel S. Hwang et al.   PHARMACEUTICAL RESEARCH

Trophic Effects of Mesenchymal Stem Cells Increase Chondrocyte Proliferation and Matrix Formation

(2011) Ling Wu et al.   TISSUE ENGINEERING PART A

Continuous Gradients of Material Composition and Growth Factors for Effective Regeneration of the Osteochondral Interface

(2011) Neethu Mohan et al.   TISSUE ENGINEERING PART A

Human articular chondrocytes secrete parathyroid hormone-related protein and inhibit hypertrophy of mesenchymal stem cells in coculture during chondrogenesis

(2010) J. Fischer et al.   ARTHRITIS AND RHEUMATISM

Osteoarthritic chondrocyte-secreted morphogens induce chondrogenic differentiation of human mesenchymal stem cells

(2010) Aereas Aung et al.   ARTHRITIS AND RHEUMATISM

In vivo ectopic chondrogenesis of BMSCs directed by mature chondrocytes

(2010) Xia Liu et al.   BIOMATERIALS

Chondrogenesis of synovium-derived mesenchymal stem cells in gene-transferred co-culture system

(2010) Rohan R. Varshney et al.   BIOMATERIALS

In vitro generation of an osteochondral interface from mesenchymal stem cell–collagen microspheres

(2010) Hiu-wa Cheng et al.   BIOMATERIALS

Treatment of articular cartilage lesions of the knee

(2010) Mazen Falah et al.   INTERNATIONAL ORTHOPAEDICS

Primary chondrocytes enhance cartilage tissue formation upon co-culture with a range of cell types

(2010) Jeanine A. A. Hendriks et al.   Soft Matter

Structured coculture of stem cells and disc cells prevent disc degeneration in a rat model

(2010) Aliza A. Allon et al.   Spine Journal

Influence of Chondrocytes on the Chondrogenic Differentiation of Adipose Stem Cells

(2010) Jai-Sun Lee et al.   TISSUE ENGINEERING PART A

Chondrogenesis and Mineralization During In Vitro Culture of Human Mesenchymal Stem Cells on Three-Dimensional Woven Scaffolds

(2010) Christoffer K. Abrahamsson et al.   TISSUE ENGINEERING PART A

Coculture of Human Mesenchymal Stem Cells and Articular Chondrocytes Reduces Hypertrophy and Enhances Functional Properties of Engineered Cartilage

(2010) Liming Bian et al.   TISSUE ENGINEERING PART A

In vitro stage-specific chondrogenesis of mesenchymal stem cells committed to chondrocytes

(2009) Wei-Hong Chen et al.   ARTHRITIS AND RHEUMATISM

The influence of degradation characteristics of hyaluronic acid hydrogels on in vitro neocartilage formation by mesenchymal stem cells

(2009) Cindy Chung et al.   BIOMATERIALS

The use of green fluorescence gene (GFP)-modified rabbit mesenchymal stem cells (rMSCs) co-cultured with chondrocytes in hydrogel constructs to reveal the chondrogenesis of MSCs

(2009) Han N. Yang et al.   BIOMATERIALS

Passaged human chondrocytes accumulate extracellular matrix when induced by bovine chondrocytes

(2009) Nazish Ahmed et al.   Journal of Tissue Engineering and Regenerative Medicine

Effect of oxygen concentration, culture format and donor variability onin vitrochondrogenesis of human adipose tissue-derived stem cells

(2009) L Pilgaard et al.   Regenerative Medicine

Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells

(2008) Michael B. Mueller et al.   ARTHRITIS AND RHEUMATISM

Variations in the ratios of co-cultured mesenchymal stem cells and chondrocytes regulate the expression of cartilaginous and osseous phenotype in alginate constructs

(2008) Xiang-tao Mo et al.   BONE

Cartilage Tissue Formation Using Redifferentiated Passaged ChondrocytesIn Vitro

(2008) Nazish Ahmed et al.   TISSUE ENGINEERING PART A