Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists

Title
Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists
Authors
Keywords
G protein-coupled receptors, CXCR4 chemokine receptor, Antagonists, Structure-based fragment virtual screening, Structure-activity relationship, 3D-QSAR
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 162, Issue -, Pages 631-649
Publisher
Elsevier BV
Online
2018-10-31
DOI
10.1016/j.ejmech.2018.10.060

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