Article
Endocrinology & Metabolism
Leweihua Lin, Tuanyu Fang, Lu Lin, Qianying Ou, Huachuan Zhang, Kaining Chen, Huibiao Quan
Summary: This study identified genetic variants associated with 2-hour postprandial glucose, glycosylated hemoglobin, and body mass index in prediabetes patients from Hainan.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pharmacology & Pharmacy
Chaiwat Washirasaksiri, Weerachai Srivanichakorn, Nutsakol Borrisut, Tullaya Sitasuwan, Rungsima Tinmanee, Chayanis Kositamongkol, Pinyapat Ariyakunaphan, Chonticha Auesomwang, Naruemit Sayabovorn, Thanet Chaisathaphol, Pochamana Phisalprapa
Summary: The incidences of diabetes and diabetic retinopathy in high-risk individuals in Thailand increase significantly with higher degrees of dysglycemia. Individuals with FPG 110-125 mg/dl and HbA1c 6.0%-6.4% are more likely to develop type 2 diabetes and diabetic retinopathy.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Endocrinology & Metabolism
Ri Liu, Lishu Gao, Lu Guo, Wenqi Xu, Shouling Wu, Dehu Tian
Summary: This study investigates the impact of FPG variability on osteoporotic fractures in the community population. By analyzing participants from three consecutive surveys, it is found that increased FPG variability is associated with an increased risk of osteoporotic fractures.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Feifei Liu, Ke Zhang, Gongbo Chen, Jie He, Mengnan Pan, Feng Zhou, Xiangxiang Wang, Jiahui Tong, Yuming Guo, Shanshan Li, Hao Xiang
Summary: This study found that exposure to PM10, PM2.5, and NO2 was associated with elevated blood sugar levels and increased incidence of diabetes in elderly Chinese populations. With the rising prevalence and incidence of diabetes in China, urgent measures to improve air quality are needed.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Medical Laboratory Technology
Geronimo Heilmann, Sandra Trenkamp, Clara Moeser, Maria Bombrich, Martin Schoen, Iryna Yurchenko, Klaus Strassburger, Marcos Matabuena Rodriguez, Oana-Patricia Zaharia, Volker Burkart, Robert Wagner, Michael Roden
Summary: Objectives of this study were to compare glucose measurements in sodium fluoride (NaF)-citrate plasma and venous whole blood and estimate the impact of these differences on diabetes and prediabetes prevalence. The study found that even with the recommended conversion factor, the glucose concentration difference remained higher in NaF-citrate plasma. This systematic bias of glucose measurements due to sampling type leads to clinically relevant higher estimates of diabetes and prediabetes prevalence.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Endocrinology & Metabolism
Mary R. R. Rooney, Michael Fang, Katherine Ogurtsova, Bige Ozkan, Justin B. B. Echouffo-Tcheugui, Edward J. J. Boyko, Dianna J. J. Magliano, Elizabeth Selvin
Summary: This study aims to estimate the global, regional, and national prevalence of prediabetes, defined as impaired glucose tolerance or impaired fasting glucose. The results show that although two-thirds of countries lack high-quality data, the global burden of prediabetes is substantial and increasing.
Article
Endocrinology & Metabolism
Yue Liu, Huijun Zhuang, Na Han, Yuxing Yang, Qiao Zhang, Nianchun Peng, Ying Hu, Lixin Shi, Hong Li
Summary: This study investigated the incidence of metabolic syndrome (MS) in people over 40 years of age with normal blood glucose levels in Guiyang's urban areas and determined the effective glycemic cutoff value for predicting MS. The results showed a correlation between increased fasting plasma glucose (FPG) and the incidence of MS, even within the normal range. The study suggests that FPG testing can be used not only for diagnosing diabetes but also as a cost-effective screening method for predicting the development of MS in the general Chinese population.
DIABETES METABOLIC SYNDROME AND OBESITY
(2023)
Article
Nutrition & Dietetics
Abhiram Charan Tej Mallu, Madavan Vasudevan, Srinivas Allanki, Abel Arul Nathan, Mahalakshmi M. Ravi, Gowri Shanker Ramanathan, Rajendra Pradeepa, Viswanathan Mohan, Madhulika Dixit
Summary: The study revealed that glucose load had specific effects on gene expression in normal glucose tolerant and prediabetic individuals, with prediabetic individuals showing altered expression of immune-related genes at fasting state, including TLR signaling, MHC class II molecules, and T-cell receptor pathways. This suggests that prediabetes may lead to constitutive TLR activation, enhanced IFN-gamma signaling, and Treg dysfunction at fasting.
CLINICAL NUTRITION
(2021)
Article
Endocrinology & Metabolism
Jung A. Kim, Ji Sung Lee, Eyun Song, Eun Roh, Ji Hee Yu, Nam Hoon Kim, Hye Jin Yoo, Ji A. Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi
Summary: This study examined the relationship between fasting plasma glucose variability and osteoporotic fractures in individuals without diabetes using a nationwide cohort database. The results suggest that FPG variability may be an independent risk factor for osteoporotic fractures in the general population without diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Jung A. Kim, Ji Sung Lee, Eyun Song, Eun Roh, Ji Hee Yu, Nam Hoon Kim, Hye Jin Yoo, Ji A. Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi
Summary: Although previous studies have linked long-term glucose variability to osteoporosis, this study is the first to investigate the relationship between glucose variability and fractures in individuals without diabetes. The results suggest that fasting plasma glucose variability may be an independent risk factor for osteoporotic fractures in the general population without diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Endocrinology & Metabolism
M. Buysschaert, M. Bergman, P. Valensi
Summary: Prediabetes is a common condition associated with an increased risk of diabetes and chronic complications. Early detection and intervention can limit the development of complications. The measurement of 1-hour post-load plasma glucose (PG) is a more predictive marker for diabetes and cardiovascular diseases. Early detection of prediabetes is crucial.
DIABETES & METABOLISM
(2022)
Article
Cardiac & Cardiovascular Systems
Ping-ping Zhang, Jie-yun Song, Li Li, Miao Xu, Hui Wang, Hai-jun Wang
Summary: This study revealed the association between two variants in the HSD17B13 gene and fasting plasma glucose levels in Chinese children, suggesting a link between HSD17B13 variants and abnormal glucose metabolism.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Article
Medical Laboratory Technology
Miaomiao Sang, Yu Liu, Tongzhi Wu, Xiaoying Zhou, Duolao Wang, Zilin Sun, Shanhu Qiu
Summary: This study found that increases in renal sodium retention and potassium excretion, as indicated by an elevated SUSPPUP, are associated with an increased prevalence of prediabetes and diabetes in Chinese community-dwellers.
CLINICA CHIMICA ACTA
(2022)
Article
Environmental Sciences
Mengyi Wang, Min Zhou, Qiyou Tan, Linling Yu, Chaoqian Dong, Ruyi Liang, Wei Liu, Yongfang Zhang, Minjing Li, XiuQuan Nie, Tao Jing, Weihong Chen
Summary: This study aimed to assess the associations between triazine herbicides and glycemia-related risk indicators in general adults. The results showed that triazine herbicides exposure was positively associated with abnormal glucose metabolism, and decreasing serum IgM partly mediated these associations among uninfected participants.
ENVIRONMENTAL POLLUTION
(2023)
Article
Endocrinology & Metabolism
Chenghu Huang, Chenhong Ren, Xiuping Xuan, Yi Luo, Caibi Peng
Summary: This study found a non-linear relationship between fasting plasma glucose (FPG) changes and the incidence of type 2 diabetes (T2D). By categorizing the FPG changes into different stages, it was possible to screen individuals at high risk of T2D.
BMC ENDOCRINE DISORDERS
(2022)