Cell competition: Emerging mechanisms to eliminate neighbors

Serpin Facilitates Tumor-Suppressive Cell Competition by Blocking Toll-Mediated Yki Activation in Drosophila

(2018) Mitsuko Katsukawa et al.   CURRENT BIOLOGY

Wingless signaling regulates winner/loser status in Minute cell competition

(2018) Nanami Akai et al.   GENES TO CELLS

A Regulatory Response to Ribosomal Protein Mutations Controls Translation, Growth, and Cell Competition

(2018) Chang-Hyun Lee et al.   DEVELOPMENTAL CELL

The ligand Sas and its receptor PTP10D drive tumour-suppressive cell competition

(2017) Masatoshi Yamamoto et al.   NATURE

Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes

(2017) Shunsuke Kon et al.   NATURE CELL BIOLOGY

Cell Competition: Mechanisms and Physiological Roles

(2016) Cristina Clavería et al.   Annual Review of Cell and Developmental Biology

Cell Competition and Its Role in the Regulation of Cell Fitness from Development to Cancer

(2016) Aida Di Gregorio et al.   DEVELOPMENTAL CELL

Slit-Robo Repulsive Signaling Extrudes Tumorigenic Cells from Epithelia

(2016) John Vaughen et al.   DEVELOPMENTAL CELL

Elimination of Unfit Cells Maintains Tissue Health and Prolongs Lifespan

(2015) Marisa M. Merino et al.   CELL

Cell competition in mouse NIH3T3 embryonic fibroblasts is controlled by the activity of Tead family proteins and Myc

(2015) H. Mamada et al.   JOURNAL OF CELL SCIENCE

EPLIN is a crucial regulator for extrusion of RasV12-transformed cells

(2015) A. Ohoka et al.   JOURNAL OF CELL SCIENCE

An ancient defense system eliminates unfit cells from developing tissues during cell competition

(2014) S. N. Meyer et al.   SCIENCE

Filamin acts as a key regulator in epithelial defence against transformed cells

(2014) Mihoko Kajita et al.   Nature Communications

Protein tyrosine phosphatase variants in human hereditary disorders and disease susceptibilities

(2013) Wiljan J.A.J. Hendriks et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

“Fitness Fingerprints” Mediate Physiological Culling of Unwanted Neurons in Drosophila

(2013) Marisa M. Merino et al.   CURRENT BIOLOGY

Competitive Interactions Eliminate Unfit Embryonic Stem Cells at the Onset of Differentiation

(2013) Margarida Sancho et al.   DEVELOPMENTAL CELL

Tissue Repair through Cell Competition and Compensatory Cellular Hypertrophy in Postmitotic Epithelia

(2013) Yoichiro Tamori et al.   DEVELOPMENTAL CELL

Myc-driven endogenous cell competition in the early mammalian embryo

(2013) Cristina Clavería et al.   NATURE

Interactions between a Receptor Tyrosine Phosphatase and a Cell Surface Ligand Regulate Axon Guidance and Glial-Neuronal Communication

(2013) Hyung-Kook (Peter) Lee et al.   NEURON

Cell competition may function either as tumour-suppressing or as tumour-stimulating factor in Drosophila

(2013) L Ballesteros-Arias et al.   ONCOGENE

Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesis

(2012) A. B. Rodrigues et al.   DEVELOPMENT

Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila

(2012) Masato Enomoto et al.   EMBO REPORTS

Loss of Scribble causes cell competition in mammalian cells

(2012) M. Norman et al.   JOURNAL OF CELL SCIENCE

Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila

(2012) Shizue Ohsawa et al.   NATURE

Cell Competition Time Line: Winners Kill Losers, which Are Extruded and Engulfed by Hemocytes

(2012) Fidel-Nicolás Lolo et al.   Cell Reports

Elimination of Oncogenic Neighbors by JNK-Mediated Engulfment in Drosophila

(2011) Shizue Ohsawa et al.   DEVELOPMENTAL CELL

Steep Differences in Wingless Signaling Trigger Myc-Independent Competitive Cell Interactions

(2011) Jean-Paul Vincent et al.   DEVELOPMENTAL CELL

Cell competition and its implications for development and cancer

(2011) Yoichiro Tamori et al.   Journal of Genetics and Genomics

Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of Yap

(2010) Ricardo M. Neto-Silva et al.   DEVELOPMENTAL CELL

Flower Forms an Extracellular Code that Reveals the Fitness of a Cell to its Neighbors in Drosophila

(2010) Christa Rhiner et al.   DEVELOPMENTAL CELL

Drosophila SPARC Is a Self-Protective Signal Expressed by Loser Cells during Cell Competition

(2010) Marta Portela et al.   DEVELOPMENTAL CELL

Involvement of Lgl and Mahjong/VprBP in Cell Competition

(2010) Yoichiro Tamori et al.   PLOS BIOLOGY

A Synaptic Vesicle-Associated Ca2+ Channel Promotes Endocytosis and Couples Exocytosis to Endocytosis

(2009) Chi-Kuang Yao et al.   CELL

Intrinsic Tumor Suppression and Epithelial Maintenance by Endocytic Activation of Eiger/TNF Signaling in Drosophila

(2009) Tatsushi Igaki et al.   DEVELOPMENTAL CELL

Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells

(2009) M. Kajita et al.   JOURNAL OF CELL SCIENCE

Characterization of the interface between normal and transformed epithelial cells

(2009) Catherine Hogan et al.   NATURE CELL BIOLOGY

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

(2008) Lixing Zhan et al.   CELL

Drosophila growth and development in the absence of dMyc and dMnt

(2007) Sarah B. Pierce et al.   DEVELOPMENTAL BIOLOGY