Connexin43 plays diverse roles in co-ordinating cell migration and wound closure events

The Effect of a Connexin43-Based Peptide on the Healing of Chronic Venous Leg Ulcers: A Multicenter, Randomized Trial

(2015) Gautam S. Ghatnekar et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

(2014) Joell L. Solan et al.   FEBS LETTERS

Connexins: Sensors of epidermal integrity that are therapeutic targets

(2014) Patricia E. Martin et al.   FEBS LETTERS

Zebrafish as a Model System to Study Skin Biology and Pathology

(2014) Qiaoli Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Connexins, a new target in wound treatment

(2014) K.Y Chin   Journal of Wound Care

14-3-3  facilitates plasma membrane delivery and function of mechanosensitive connexin 43 hemichannels

(2013) N. Batra et al.   JOURNAL OF CELL SCIENCE

Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size

(2013) C. A. Dunn et al.   JOURNAL OF CELL SCIENCE

Peptides and peptide-derived molecules targeting the intracellular domains of Cx43: Gap junctions versus hemichannels

(2013) Jegan Iyyathurai et al.   NEUROPHARMACOLOGY

Reduced Cx43 Expression Triggers Increased Fibrosis Due to Enhanced Fibroblast Activity

(2012) John A. Jansen et al.   Circulation-Arrhythmia and Electrophysiology

Cell motility in models of wounded human skin is improved by Gap27 despite raised glucose, insulin and IGFBP-5

(2012) Catherine S. Wright et al.   EXPERIMENTAL CELL RESEARCH

Manipulating Connexin Communication Channels: Use of Peptidomimetics and the Translational Outputs

(2012) W. Howard Evans et al.   JOURNAL OF MEMBRANE BIOLOGY

Gap26, a connexin mimetic peptide, inhibits currents carried by connexin43 hemichannels and gap junction channels

(2012) T. Desplantez et al.   PHARMACOLOGICAL RESEARCH

Targeting Cx43 and N-Cadherin, Which Are Abnormally Upregulated in Venous Leg Ulcers, Influences Migration, Adhesion and Activation of Rho GTPases

(2012) Ariadna Mendoza-Naranjo et al.   PLoS One

RhoA GTPase Switch Controls Cx43-Hemichannel Activity through the Contractile System

(2012) Raf Ponsaerts et al.   PLoS One

The connexin mimetic peptide Gap27 increases human dermal fibroblast migration in hyperglycemic and hyperinsulinemic conditions in vitro

(2011) Catherine S. Wright et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1

(2011) J. Matthew Rhett et al.   MOLECULAR BIOLOGY OF THE CELL

Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis

(2011) Cory L. Simpson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Connexin43 Modulates Cell Polarity and Directional Cell Migration by Regulating Microtubule Dynamics

(2011) Richard Francis et al.   PLoS One

Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity

(2010) Raf Ponsaerts et al.   FASEB JOURNAL

Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells

(2010) Simone Pollok et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The carboxy-terminal tail of connexin43 gap junction protein is sufficient to mediate cytoskeleton changes in human glioma cells

(2010) Sophie Crespin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Connexin43 phosphorylation: structural changes and biological effects

(2009) Joell L. Solan et al.   BIOCHEMICAL JOURNAL

The extracellular matrix controls gap junction protein expression and function in postnatal hippocampal neural progenitor cells

(2009) Sophie Imbeault et al.   BMC NEUROSCIENCE

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Connexin43 carboxyl-terminal peptides reduce scar progenitor and promote regenerative healing following skin wounding

(2009) Gautam S Ghatnekar et al.   Regenerative Medicine

Connexin mimetic peptides improve cell migration rates of human epidermal keratinocytes and dermal fibroblasts in vitro

(2009) Catherine S. Wright et al.   WOUND REPAIR AND REGENERATION

The skin: an indispensable barrier

(2008) Ehrhardt Proksch et al.   EXPERIMENTAL DERMATOLOGY

A Murine Living Skin Equivalent Amenable to Live-Cell Imaging: Analysis of the Roles of Connexins in the Epidermis

(2007) Eve E. Kandyba et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY