Morphology and Composition of the Inner Limiting Membrane: Species-Specific Variations and Relevance toward Drug Delivery Research

In vitro and ex vivo models to study drug delivery barriers in the posterior segment of the eye

(2018) Karen Peynshaert et al.   ADVANCED DRUG DELIVERY REVIEWS

Müller glial cells of the primate foveola: An electron microscopical study

(2018) Steffen Syrbe et al.   EXPERIMENTAL EYE RESEARCH

Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain

(2018) Jennifer A. Sullivan et al.   GENE THERAPY

Efficacy and Safety of Glycosidic Enzymes for Improved Gene Delivery to the Retina following Intravitreal Injection in Mice

(2018) Jasmina Cehajic-Kapetanovic et al.   Molecular Therapy-Methods & Clinical Development

Transduction Patterns of Adeno-associated Viral Vectors in a Laser-Induced Choroidal Neovascularization Mouse Model

(2018) Si Hyung Lee et al.   Molecular Therapy-Methods & Clinical Development

Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy

(2017) Thomas F Martens et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina

(2017) D G Hickey et al.   GENE THERAPY

Retinal gene delivery enhancement by lycopene incorporation into cationic niosomes based on DOTMA and polysorbate 60

(2017) Mohamed Mashal et al.   JOURNAL OF CONTROLLED RELEASE

Ocular Pharmacokinetics of Therapeutic Antibodies Given by Intravitreal Injection: Estimation of Retinal Permeabilities Using a 3-Compartment Semi-Mechanistic Model

(2017) Laurence A. Hutton-Smith et al.   MOLECULAR PHARMACEUTICS

Hyaluronic Acid Coated Albumin Nanoparticles for Targeted Peptide Delivery to the Retina

(2017) Di Huang et al.   MOLECULAR PHARMACEUTICS

A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A

(2017) Müjdat Zeybel et al.   MOLECULAR THERAPY

Improving our understanding, and detection, of glaucomatous damage: An approach based upon optical coherence tomography (OCT)

(2017) Donald C. Hood   PROGRESS IN RETINAL AND EYE RESEARCH

Structural recovery of the retina in a retinoschisin-deficient mouse after gene replacement therapy by solid lipid nanoparticles

(2016) P.S. Apaolaza et al.   BIOMATERIALS

The influence of the polar head-group of synthetic cationic lipids on the transfection efficiency mediated by niosomes in rat retina and brain

(2016) E. Ojeda et al.   BIOMATERIALS

Heparan Sulfate Binding Promotes Accumulation of Intravitreally Delivered Adeno-associated Viral Vectors at the Retina for Enhanced Transduction but Weakly Influences Tropism

(2016) Kenton T. Woodard et al.   JOURNAL OF VIROLOGY

Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors

(2016) Sanford L. Boye et al.   JOURNAL OF VIROLOGY

Effective Retinal Penetration of Lipophilic and Lipid-Conjugated Hydrophilic Agents Delivered by Engineered Liposomes

(2016) Junsung Lee et al.   MOLECULAR PHARMACEUTICS

Gene Therapy and Stem Cell Transplantation in Retinal Disease: The New Frontier

(2016) Robert E. MacLaren et al.   OPHTHALMOLOGY

Vitrectomy Before Intravitreal Injection of AAV2/2 Vector Promotes Efficient Transduction of Retinal Ganglion Cells in Dogs and Nonhuman Primates

(2016) Kizito-Tshitoko Tshilenge et al.   Human Gene Therapy Methods

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(2016)   GLIA

Performance benchmarking of four cell-free protein expression systems

(2015) Dejan Gagoski et al.   BIOTECHNOLOGY AND BIOENGINEERING

New concepts in basement membrane biology

(2015) Willi Halfter et al.   FEBS Journal

The Ultrastructural Localization of Type II, IV, and VI Collagens at the Vitreoretinal Interface

(2015) Shao Chong Bu et al.   PLoS One

The pros and cons of vertebrate animal models for functional and therapeutic research on inherited retinal dystrophies

(2015) Ralph W.N. Slijkerman et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Proteomic View of Basement Membranes from Human Retinal Blood Vessels, Inner Limiting Membranes, and Lens Capsules

(2014) Guy Uechi et al.   JOURNAL OF PROTEOME RESEARCH

A Novel Formulation Based on 2,3-Di(tetradecyloxy)propan-1-amine Cationic Lipid Combined with Polysorbate 80 for Efficient Gene Delivery to the Retina

(2014) Gustavo Puras Ochoa et al.   PHARMACEUTICAL RESEARCH

Pharmacokinetics, pharmacodynamics and pre-clinical characteristics of ophthalmic drugs that bind VEGF

(2014) Michael W Stewart   Expert Review of Clinical Pharmacology

Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach

(2013) F M Mowat et al.   GENE THERAPY

The Bi-Functional Organization of Human Basement Membranes

(2013) Willi Halfter et al.   PLoS One

In Vivo-Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous

(2013) D. Dalkara et al.   Science Translational Medicine

Laminins in basement membrane assembly

(2013) Erhard Hohenester et al.   Cell Adhesion & Migration

Laser Photocoagulation Enhances Adeno-Associated Viral Vector Transduction of Mouse Retina

(2013) Si Hyung Lee et al.   Human Gene Therapy Methods

The movement of self-assembled amphiphilic polymeric nanoparticles in the vitreous and retina after intravitreal injection

(2012) Heebeom Koo et al.   BIOMATERIALS

Effective electrophoretic mobilities and charges of anti-VEGF proteins determined by capillary zone electrophoresis

(2011) S. Kevin Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Molecular interactions in the retinal basement membrane system: A proteomic approach

(2010) Manimalha Balasubramani et al.   MATRIX BIOLOGY

Age-dependent changes in the structure, composition and biophysical properties of a human basement membrane

(2010) Joseph Candiello et al.   MATRIX BIOLOGY

GFAP-Driven GFP Expression in Activated Mouse Müller Glial Cells Aligning Retinal Blood Vessels Following Intravitreal Injection of AAV2/6 Vectors

(2010) Wendy M. Aartsen et al.   PLoS One

POSTERIOR VITREOUS DETACHMENT WITH MICROPLASMIN ALTERS THE RETINAL PENETRATION OF INTRAVITREAL BEVACIZUMAB (AVASTIN) IN RABBIT EYES

(2010) David T Goldenberg et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Clinical and histological findings after intravitreal injection of bevacizumab (Avastin®) in a porcine model of choroidal neovascularization

(2009) Nathan Lassota et al.   ACTA OPHTHALMOLOGICA

Intravitreal delivery of AAV8 retinoschisin results in cell type-specific gene expression and retinal rescue in the Rs1-KO mouse

(2009) T K Park et al.   GENE THERAPY

Changes in Adeno-Associated Virus-Mediated Gene Delivery in Retinal Degeneration

(2009) Kathleen D. Kolstad et al.   HUMAN GENE THERAPY

Vesicular phospholipid gel-based depot formulations for pharmaceutical proteins: Development and in vitro evaluation

(2009) W. Tian et al.   JOURNAL OF CONTROLLED RELEASE

Inner Limiting Membrane Barriers to AAV-mediated Retinal Transduction From the Vitreous

(2009) Deniz Dalkara et al.   MOLECULAR THERAPY

A Novel Adeno-Associated Viral Variant for Efficient and Selective Intravitreal Transduction of Rat Müller Cells

(2009) Ryan R. Klimczak et al.   PLoS One

INTRAVITREAL ALEMTUZUMAB PENETRATES FULL-THICKNESS RETINA IN RABBIT EYES

(2009) NOHA S. EKDAWI et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

(2008) M Hellström et al.   GENE THERAPY

Insertion of the Designed Helical Linker Led to Increased Expression of Tf-Based Fusion Proteins

(2008) Nurmamet Amet et al.   PHARMACEUTICAL RESEARCH

Page mode reading with simulated scotomas: Oculo-motor patterns

(2008) Anne-Catherine Scherlen et al.   VISION RESEARCH