The ryanodine receptor provides high throughput Ca2+-release but is precisely regulated by networks of associated proteins: a focus on proteins relevant to phosphorylation

FKBP12.6 Activates RyR1: Investigating the Amino Acid Residues Critical for Channel Modulation

(2014) Elisa Venturi et al.   BIOPHYSICAL JOURNAL

Genetic ablation of ryanodine receptor 2 phosphorylation at Ser-2808 aggravates Ca2+-dependent cardiomyopathy by exacerbating diastolic Ca2+release

(2014) Bin Liu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Structure of a mammalian ryanodine receptor

(2014) Ran Zalk et al.   NATURE

Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution

(2014) Zhen Yan et al.   NATURE

FK506-binding protein 1b/12.6: A key to aging-related hippocampal Ca2+ dysregulation?

(2013) J.C. Gant et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

ß-Adrenergic Stimulation Increases RyR2 Activity via Intracellular Ca2+ and Mg2+ Regulation

(2013) Jiao Li et al.   PLoS One

Structural determination of the phosphorylation domain of the ryanodine receptor

(2012) Parveen Sharma et al.   FEBS Journal

Disparities in the association of the ryanodine receptor and the FK506-binding proteins in mammalian heart

(2012) S. Zissimopoulos et al.   JOURNAL OF CELL SCIENCE

PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity

(2012) Nina D. Ullrich et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

FKBP12 Activates the Cardiac Ryanodine Receptor Ca2+-Release Channel and Is Antagonised by FKBP12.6

(2012) Elena Galfré et al.   PLoS One

Disease Mutations in the Ryanodine Receptor Central Region: Crystal Structures of a Phosphorylation Hot Spot Domain

(2012) Zhiguang Yuchi et al.   STRUCTURE

Ca2+-Dependent Phosphorylation of RyR2 Can Uncouple Channel Gating from Direct Cytosolic Ca2+ Regulation

(2011) Simon Carter et al.   JOURNAL OF MEMBRANE BIOLOGY

Disrupting Function of FK506-Binding Protein 1b/12.6 Induces the Ca2+-Dysregulation Aging Phenotype in Hippocampal Neurons

(2011) J. C. Gant et al.   JOURNAL OF NEUROSCIENCE

Kinetics of FKBP12.6 Binding to Ryanodine Receptors in Permeabilized Cardiac Myocytes and Effects on Ca Sparks

(2010) Tao Guo et al.   CIRCULATION RESEARCH

Illicit organogenesis

(2010) Mario Thevis et al.   Organogenesis

Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle: the role of FK506 binding proteins and mTOR

(2009) D MacMillan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating

(2009) Montserrat Samsó et al.   PLOS BIOLOGY

FKBP12.6 disruption impairs glucose-induced insulin secretion

(2008) Naoya Noguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS