MIB1 mutations reduce Notch signaling activation and contribute to congenital heart disease

Genetic analysis of rare coding mutations in CELSR1-3 in Chinese Congenital Heart and Neural Tube Defects

(2016) X. Qiao et al.   CLINICAL SCIENCE

Structure and function of the Mind bomb E3 ligase in the context of Notch signal transduction

(2016) Bingqian Guo et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The E3 ubiquitin ligase Mib1 regulates Plk4 and centriole biogenesis

(2015) L.  ajanek et al.   JOURNAL OF CELL SCIENCE

Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth

(2015) Joseph Mertz et al.   MOLECULAR & CELLULAR PROTEOMICS

New Classes of Mind Bomb-Interacting Proteins Identified from Yeast Two-Hybrid Screens

(2014) Li-Chuan Tseng et al.   PLoS One

Genetic and functional genomics approaches targeting the Notch pathway in cardiac development and congenital heart disease

(2013) D. MacGrogan et al.   Briefings in Functional Genomics

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy

(2013) Guillermo Luxán et al.   NATURE MEDICINE

The E3 Ligase Mind Bomb-1 (Mib1) Modulates Delta-Notch Signaling to Control Neurogenesis and Gliogenesis in the Developing Spinal Cord

(2012) Kyungjoon Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E3 ubiquitin ligase MIB1 negatively regulates basal IκBα level and modulates NF-κB activation

(2011) Li-Juan Liu et al.   CELL RESEARCH

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

(2011) Jason D. Berndt et al.   JOURNAL OF CELL BIOLOGY

Mib-Jag1-Notch signalling regulates patterning and structural roles of the notochord by controlling cell-fate decisions

(2010) M. Yamamoto et al.   DEVELOPMENT

Control of Notch-ligand endocytosis by ligand-receptor interaction

(2010) E. M. Hansson et al.   JOURNAL OF CELL SCIENCE

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Notch Signaling in Cardiac Development and Disease

(2009) José Luis de la Pompa   PEDIATRIC CARDIOLOGY

Notch Signaling Activation in Human Embryonic Stem Cells Is Required for Embryonic, but Not Trophoblastic, Lineage Commitment

(2008) Xiaobing Yu et al.   Cell Stem Cell

Notch Signaling in Cardiac Development

(2008) Kyle Niessen et al.   CIRCULATION RESEARCH

The multifaceted role of Notch in cardiac development and disease

(2007) Frances A. High et al.   NATURE REVIEWS GENETICS