Review
Materials Science, Ceramics
Sotoudeh Davaie, Tabassom Hooshmand, Sajjad Ansarifard
Summary: This study systematically reviewed the use of different types of bioceramics as direct dental pulp capping materials for dentin regeneration in permanent teeth. It found that calcium silicate-based materials, MTA, and Biodentine are currently the most effective bioceramics for this purpose, with calcium phosphates showing potential as future alternatives. Further well-designed in vitro and clinical studies are needed to confirm the most appropriate bioceramics for direct dental pulp capping procedures.
CERAMICS INTERNATIONAL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Mahmoud Kayad, Azza Koura, Amira El-Nozahy
Summary: This study compared the effects of TheraCal LC and biodentine on direct pulp capping using a rabbit model. The results showed that biodentine had a thicker and more continuous dentine bridge compared to TheraCal LC. Both materials had a similar inflammatory effect on the pulp.
CLINICAL ORAL INVESTIGATIONS
(2023)
Review
Biochemistry & Molecular Biology
Mihai Andrei, Raluca Paula Vacaru, Anca Coricovac, Radu Ilinca, Andreea Cristiana Didilescu, Ioana Demetrescu
Summary: The vitality of dental pulp is essential for maintaining the health and functionality of the tooth. Hydraulic calcium-silicate cements can stimulate reparative dentinogenesis in direct pulp capping procedures, leading to the formation of new dentin bridges. Different degrees of pulp inflammatory response and dentin bridge formation were observed during pulp healing, showing positive effects on tertiary dentin formation and pulp vitality preservation.
Article
Dentistry, Oral Surgery & Medicine
Chawan Manaspon, Chavin Jongwannasiri, Sujin Chumprasert, Noppadol Sa-Ard-Iam, Rangsini Mahanonda, Prasit Pavasant, Thantrira Porntaveetus, Thanaphum Osathanon
Summary: The study found that ProRoot(R) MTA and Biodentine(TM) have favorable in vitro biocompatibility and bioactive properties on human dental pulp stem cells, suggesting their superior regenerative potential compared with DyCal(R) and TheraCal(TM).
Article
Dentistry, Oral Surgery & Medicine
Maria Luisa Leite, Caroline Anselmi, Igor Paulino Mendes Soares, Adriana Pigozzo Manso, Josimeri Hebling, Ricardo Marins Carvalho, Carlos Alberto de Souza Costa
Summary: This study developed and characterized different formulations of chitosan scaffolds associated with calcium silicate and evaluated their chemotactic and bioactive potential on human dental pulp cells. The results showed that increasing the amount of calcium silicate in the chitosan scaffold promoted cell migration, viability, proliferation, and odontogenic differentiation.
Article
Dentistry, Oral Surgery & Medicine
Cem Peskersoy, Jusuf Lukarcanin, Murat Turkun
Summary: The study aimed to investigate the effectiveness of different calcium silicate-based materials in pulp capping. MTA+ and Biodentine showed the highest clinical and radiographic success rates, while Theracal LC group had slightly better results than Dycal group. Pulp exposure size only affected the success of materials in light-cured groups, with MTA+ and Biodentine performing better in large pulp exposures. After 36 months, MTA+ and Biodentine were found to be suitable materials for direct pulp capping in permanent teeth.
JOURNAL OF DENTAL SCIENCES
(2021)
Article
Dentistry, Oral Surgery & Medicine
Nur Sahin, Suna Saygili, Merve Akcay
Summary: This study evaluated the success of three different pulp-capping materials in one-stage indirect pulp treatment of primary teeth. While the clinical and radiographic success rates were similar among the materials, the histological examination showed that resin-based materials like TheraCal LC may negatively impact pulp status. Resin-free calcium silicate-based materials seem to be more favorable in long-term success of indirect pulp treatment in young-age groups.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Materials Science, Multidisciplinary
Wei-Ting Kuo, Xin Li, Fang-Yuan Chen, Yan-Jie Wang, Zhi Chen, Shinn-Jyh Ding, Lu Zhang
Summary: The study revealed that RDSC is more prone to discoloration compared to other pulp-capping agents, while showing significant potential in promoting dentin bridge formation, suggesting its recommendation as a pulp-capping agent in non-aesthetic areas.
FRONTIERS IN MATERIALS
(2021)
Article
Chemistry, Physical
Yemi Kim, Donghee Lee, Hye-Min Kim, Minjoo Kye, Sin-Young Kim
Summary: The study compared the effects of different pulp capping materials on the viability and odontogenic differentiation of human dental pulp stem cells, finding that all materials except Dycal were favorable for hDPSC viability. ProRoot MTA and TheraCal LC showed higher expression of Runx2 compared to Biodentine, indicating their potential in promoting odontogenic differentiation. Future studies should further explore the odontogenic potential of pulp capping materials.
Article
Chemistry, Multidisciplinary
Seref Nur Mutlu, Makbule Bilge Akbulut
Summary: The objective of this study was to analyze the color consistency of three materials (Biodentine, Angelus MTA, and BIOfactor MTA) when exposed to different irrigation solutions and their impact on tooth discoloration. The results showed that Biodentine and BIOfactor MTA had similar color changes in all solutions. Angelus MTA displayed more discoloration when soaked in sodium hypochlorite (NaOCl). Biodentine caused the most significant color shifts on teeth at the third and sixth months.
APPLIED SCIENCES-BASEL
(2023)
Article
Social Sciences, Interdisciplinary
Romulo Guillermo Lopez Torres, Veronica Alejandra Salame Ortiz, Fanny del Rocio Lozada Lopez
Summary: This study analyzed the success rates of different materials used in Direct Pulp Protection (DPP) and identified the favorable conditions to maintain this treatment as a valid therapeutic option.
REVISTA UNIVERSIDAD Y SOCIEDAD
(2022)
Article
Dentistry, Oral Surgery & Medicine
Cihan Kuden, Seda Nur Karakas, Sevde Gul Batmaz
Summary: The study compared the cytotoxicity, residual monomer release, degree of conversion, calcium ion release, and crystal structure of TheraCal PT (ThPT), TheraCal LC (ThLC), and mineral trioxide aggregate (MTA). The results showed that MTA had lower cytotoxicity and higher calcium ion release compared to ThLC and ThPT.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
M. Chung, S. Lee, S. Kim, E. Kim
Summary: Previous studies have evaluated the effects of calcium silicate cements (CSCs) on normal dental pulp, but limited research has been done on inflamed pulp. This study aimed to investigate the inflammatory response and odontogenic differentiation of inflamed rat dental pulp after direct pulp capping with CSCs. The results showed that pulpal inflammation and incomplete dentine bridge formation were still present in most specimens at 4 weeks after pulp capping.
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
A. Abou ElReash, H. Hamama, M. Grawish, M. Saeed, A. M. Zaen El-Din, M. A. Shahin, W. Zhenhuan, X. Xiaoli
Summary: In a laboratory setting, ACTIVA, MTA-HP, and iRoot-BP-Plus demonstrated significant promotion of hDPSCs proliferation, mineralization, and attachment compared to the control group. iRoot-BP-Plus surfaces showed the highest cellular attachment, followed by MTA-HP, while ACTIVA group exhibited the lowest attachment. Significant differences were observed in mineralizing nodule formation among different experimental groups.
INTERNATIONAL ENDODONTIC JOURNAL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ahmad S. Al-Hiyasat, Dana M. Ahmad, Yousef S. Khader
Summary: Variation in composition of calcium silicate-based materials and contact with blood can influence color change of coronal tooth structure. WMTA and GMTA caused the most severe discoloration, while Biodentine caused the least color change but was most affected by blood.