Review
Surgery
Brian Fiani, Imran Siddiqi, Daniel Chacon, Ryan Arthur Figueras, Preston Rippe, Michael Kortz, Juliana Runnels
Summary: The study evaluates the use of the paracoccygeal transsacral approach for axial lumbosacral interbody fusion, showing high fusion rates, improvements in pain and function, and low complication rates. However, there is a lack of long-term comparative data regarding the outcomes of this technique compared to traditional alternatives and other minimally invasive techniques.
SPINE SURGERY AND RELATED RESEARCH
(2021)
Article
Medicine, General & Internal
Masakazu Nagamatsu, Sameer Ruparel, Masato Tanaka, Yoshihiro Fujiwara, Koji Uotani, Shinya Arataki, Taro Yamauchi, Yoshiyuki Takeshita, Rika Takamoto, Shinsuke Moriue
Summary: The study evaluated 3D lumbosacral vascular anatomy using a non-enhanced MRI and CT medical image fusion technique, finding it to be very useful for OLIF51, especially for patients in whom the use of contrast medium is contraindicated.
Review
Biotechnology & Applied Microbiology
Ruofan Wang, Zenghui Wu
Summary: Finite element analysis (FEA) is a widely used tool that has contributed to a better understanding of the spine and its behavior, as well as assisting in the design and application of spinal interbody cages (ICs). FEA allows for thorough testing of new designs before manufacturing, examining biomechanical responses and spinal fusion processes that cannot easily be experimented upon in vivo. This paper reviews the recent progress of FEA in spinal ICs over the last six years and discusses its limitations and future advancements.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biology
Wei Fan, Chi Zhang, Qing-Dong Wang, Li-Xin Guo, Ming Zhang
Summary: The biomechanical effects of topping-off instrumentation on the sacroiliac joint (SIJ) after lumbosacral fusion were investigated. It was found that the use of topping-off devices increased motion, stress, and ligament strain at the SIJ, suggesting a higher risk of degeneration and pain compared to fusion alone.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Orthopedics
Aixing Pan, Fengqi Cheng, Zihao Ding, Li Guan, Wenguan Xie, Yong Hai, Yuzeng Liu
Summary: This study summarizes the surgical experience of patients with lumbosacral degenerative diseases who underwent LP-PLSIF. LP-PLSIF is a safe and effective surgical technique that offers less invasiveness and better clinical improvement.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Po-Kuan Wu, Meng-Huang Wu, Cheng-Min Shih, Yen-Kuang Lin, Kun-Hui Chen, Chien-Chou Pan, Tsung-Jen Huang, Ching-Yu Lee, Cheng-Hung Lee
Summary: This study compared the impact of ALIF and TLIF treatments on ASP, showing no significant difference in the incidence of adjacent segment pathology between the two. However, ALIF was found to be more beneficial in maintaining lumbar lordosis.
Article
Clinical Neurology
Ifije E. Ohiorhenuan, Nikolay L. Martirosyan, Joshua T. Wewel, Soumya Sagar, Juan S. Uribe
Summary: Transitional psoas anatomy is common in patients undergoing L4/5 LLIF surgery. With careful identification of the lumbar plexus and judicious retraction, transpsoas LLIF can be safely performed in these patients.
WORLD NEUROSURGERY
(2021)
Article
Orthopedics
Jun Sun, Qiuan Wang, Dazhao Cai, Wenxiang Gu, Yiming Ma, Yang Sun, Yangyang Wei, Feng Yuan
Summary: The study compared the biomechanical behavior of cervical spines after implanting ZK60 and titanium fusion cages. Results showed that ZK60 increased stress stimulation to bone grafts compared to titanium cages due to reduced stress shielding effects. Additionally, a lattice-optimized porous cage design exhibited improved biomechanical properties.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Orthopedics
Jinping Liu, Rong Xie, Cynthia T. Chin, Priya Rajagopalan, Ping-Guo Duan, Bo Li, Shane Burch, Sigurd H. Berven, Praveen V. Mummaneni, Dean Chou
Summary: This study aimed to evaluate the realistic lumbosacral arthrodesis rates following ALIF and TLIF in patients with degenerative spondylolisthesis as measured by CT and radiology. The results showed that the ALIF group had a higher rate of solid radiographic fusions and the TLIF group had a higher rate of indeterminate fusion at the last follow-up. Radiographic pseudarthrosis did not differ significantly between the two groups.
ORTHOPAEDIC SURGERY
(2023)
Article
Clinical Neurology
Ali Kiapour, Elie Massaad, Amin Joukar, Muhamed Hadzipasic, Ganesh M. Shankar, Vijay K. Goel, John H. Shin
Summary: This study evaluates the mechanical stability and biomechanical properties of various interbody fixation techniques, and finds that supplemental posterior instrumentation improves stability for all interbody techniques.
JOURNAL OF NEUROSURGERY-SPINE
(2022)
Article
Chemistry, Multidisciplinary
Jinlai Qi, Youping Gong, Honghao Chen, Junling He, Zizhou Qiao, Yi Chen, Huifeng Shao, Wenxin Li, Guojin Chen, Maofa Wang, Chuanping Zhou, Xiang Zhang
Summary: The study proposed a fusion cage inner hole design method based on controllable TPMS-P to address the mismatch between the comprehensive mechanical properties of the fusion cage and the human body. By optimizing the topology of the porous structure implants, precise control of the overall comprehensive mechanical properties was achieved, resulting in an optimized model that matched the mechanical properties of the fusion cage.
APPLIED SCIENCES-BASEL
(2021)
Article
Computer Science, Interdisciplinary Applications
Wei Fan, Li-Xin Guo
Summary: The topping-off technique can reduce disc stress at the transition segment (L3-L4), while slightly increasing disc stress at its supra-adjacent segment (L2-L3). Bony fusion can decrease stress in L4 inferior endplate and rigid stabilizer, while having nearly no effect on stress in DIAM and L3-L4 disc.
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2021)
Article
Biophysics
Ali Kiapour, Elie Massaad, Manoj K. Kodigudla, Amey Kelkar, Matthew R. Begley, Vijay K. Goel, Jon E. Block, John H. Shin
Summary: The objective of this study was to compare the resistance to subsidence of a novel 3D-printed spinal inter-body titanium implant with a predicate polymeric annular cage. The truss implant demonstrated a significant increase in resistance to subsidence with an increase in line length contact interface corresponding to implant length, regardless of subsidence rate or bone density. In comparison, annular cages showed only a modest increase in resistance to subsidence. Clinical studies are needed to support the findings of this biomechanical research.
JOURNAL OF BIOMECHANICS
(2023)
Article
Biotechnology & Applied Microbiology
Honghao Yang, Aixing Pan, Yong Hai, Fengqi Cheng, Hongtao Ding, Yuzeng Liu
Summary: This study compared the biomechanical performance of combining multiple pelvic screws and multirod construct to other advanced sacropelvic fixation constructs for the augmentation of lumbosacral junction in long spinal fusion surgery through finite element analysis. The results showed that both multiple pelvic screws and multirod construct could increase the mechanical stability of lumbosacral junction and reduce stress on instrumentation, cages, S1 superior endplate, and sacrum. The MS-MR construct was the most adequate to reduce the risk of lumbosacral pseudarthrosis, implant failure, and sacrum fracture. This study provides important evidence for the application of MS-MR construct in clinical settings.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Brecht Van Berkel, Gwendolien Smets, Gertjan Van Schelverghem, Elien Houben, Dieter Peuskens, Thomas Daenekindt, Eveleen Buelens, Frank Weyns, Joris Nens, Albrecht Houben, Sofie Van Cauter
Summary: In this study, the use of iCT was found to significantly reduce radiation exposure to operating room staff, but increase the radiation dose to the patient and prolong operative time in posterior intervertebral lumbar fusion procedures compared to C-arm fluoroscopy.
APPLIED SCIENCES-BASEL
(2021)
Article
Biophysics
Tingyang Xing, Qiuping Qian, Hao Ye, Zhihui Wang, Yanyan Jin, Ningxia Zhang, Meiyan Wang, Yunlong Zhou, Xiaoqing Gao, Lijun Wu
Summary: This paper proposes a SERS substrate made of helical gold nanoparticles synthesized by L-GSH. The substrate has a complex concave surface and symmetry breaking structure, resulting in large surface specific area and uneven conduction electrons distribution for sharp tips. Experimental and numerical simulation results demonstrate the impressive enhancement performance of this nanostructure under off-resonant condition. Additionally, the substrate achieves a detection limit of 0.62 mg/kg for thiram on pear, indicating its potential application.
BIOSENSORS & BIOELECTRONICS
(2022)