The Secret Role of microRNAs in Cancer Stem Cell Development and Potential Therapy: A Notch-Pathway Approach

Abstract 1977: Therapeutic miRNAs targeted selectively to tumors by mesenchymal stem cell derived microparticles

(2015) Marianna Prokopi et al.   CANCER RESEARCH

A microRNA miR-34a-Regulated Bimodal Switch Targets Notch in Colon Cancer Stem Cells

(2013) Pengcheng Bu et al.   Cell Stem Cell

Notch Pathway Activity Identifies Cells with Cancer Stem Cell-like Properties and Correlates with Worse Survival in Lung Adenocarcinoma

(2013) K. A. Hassan et al.   CLINICAL CANCER RESEARCH

miRNA profiling of cancer

(2013) Gianpiero Di Leva et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors

(2013) Juan-Miguel Mosquera et al.   GENES CHROMOSOMES & CANCER

Cancer stem cell theory: therapeutic implications for nanomedicine

(2013) Jian Huang et al.   International Journal of Nanomedicine

Extracellular communication via microRNA: lipid particles have a new message

(2013) Katey J. Rayner et al.   JOURNAL OF LIPID RESEARCH

MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines

(2013) Pasqualino de Antonellis et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The miR-1-NOTCH3-Asef Pathway Is Important for Colorectal Tumor Cell Migration

(2013) Shiori Furukawa et al.   PLoS One

Differential effects of miR-34c-3p and miR-34c-5p on the proliferation, apoptosis and invasion of glioma cells

(2013) ZHENDONG WU et al.   Oncology Letters

Causes and Consequences of MicroRNA Dysregulation

(2012) Marilena V. Iorio et al.   CANCER JOURNAL

Human skin cancer stem cells: a tale of mice and men

(2012) Chantal S. Colmont et al.   EXPERIMENTAL DERMATOLOGY

Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI

(2011) Yi-Ping Yang et al.   BIOMATERIALS

MicroRNA-21: A novel therapeutic target in human cancer

(2011) Xuan Pan et al.   CANCER BIOLOGY & THERAPY

Potential implications of mesenchymal stem cells in cancer therapy

(2011) Long-Jun Dai et al.   CANCER LETTERS

A NOTCH3-Mediated Squamous Cell Differentiation Program Limits Expansion of EMT-Competent Cells That Express the ZEB Transcription Factors

(2011) S. Ohashi et al.   CANCER RESEARCH

Mechanisms of microRNA deregulation in human cancer

(2011) Shan Deng et al.   CELL CYCLE

Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells

(2011) Diana M Vallejo et al.   EMBO JOURNAL

The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells

(2011) Simone Brabletz et al.   EMBO JOURNAL

Functions of Noncoding RNAs in Neural Development and Neurological Diseases

(2011) Shan Bian et al.   MOLECULAR NEUROBIOLOGY

Activated K-ras and INK4a/Arf Deficiency Cooperate During the Development of Pancreatic Cancer by Activation of Notch and NF-κB Signaling Pathways

(2011) Zhiwei Wang et al.   PLoS One

Targeting Notch signaling pathway to overcome drug resistance for cancer therapy

(2010) Zhiwei Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells

(2010) Ronald T.K. Pang et al.   CARCINOGENESIS

Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways

(2010) Zhiwei Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Functional elucidation of MiR-34 in osteosarcoma cells and primary tumor samples

(2009) Chunlei He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures

(2009) M. Prokopi et al.   BLOOD

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

(2009) Y. Li et al.   CANCER RESEARCH

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

MicroRNA reexpression as differentiation therapy in cancer

(2009) Prasun J. Mishra et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma

(2009) Livia Garzia et al.   PLoS One

MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells

(2009) Qing Ji et al.   PLoS One

Emerging role of Notch in stem cells and cancer

(2008) Zhiwei Wang et al.   CANCER LETTERS

Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms

(2008) Lorenz Poellinger et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

MicroRNAs: Key Modulators of Posttranscriptional Gene Expression

(2008) Steven P. O'Hara et al.   GASTROENTEROLOGY

Notch tumor suppressor function

(2008) G P Dotto   ONCOGENE

A microRNA DNA methylation signature for human cancer metastasis

(2008) A. Lujambio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal Stem Cells: An Emerging Tool for Cancer Targeting and Therapy

(2008) Vanessa Fritz et al.   Current Stem Cell Research & Therapy