Molecular docking studies of coumarin hybrids as potential acetylcholinesterase, butyrylcholinesterase, monoamine oxidase A/B and β-amyloid inhibitors for Alzheimer’s disease

Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease

(2017) Jacques Joubert et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, in vitro acetylcholinesterase inhibitory activity and molecular docking of new acridine-coumarin hybrids

(2017) Slavka Hamulakova et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors

(2017) Fatih Sonmez et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Design, characterization, in vitro antibacterial, antitubercular evaluation and structure–activity relationships of new hydrazinyl thiazolyl coumarin derivatives

(2017) Samina KhanYusufzai et al.   MEDICINAL CHEMISTRY RESEARCH

Coumarin derivatives as potential inhibitors of acetylcholinesterase: Synthesis, molecular docking and biological studies

(2016) Shaffali Singla et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of coumarin derivatives as novel acetylcholinesterase inhibitors that attenuate H2O2-induced apoptosis in SH-SY5Y cells

(2016) Dahong Yao et al.   BIOORGANIC CHEMISTRY

Synthesis and anticholinesterase activity of coumarin-3-carboxamides bearing tryptamine moiety

(2016) Samaneh Ghanei-Nasab et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents

(2016) Jeelan Basha Shaik et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Thiosemicarbazone modification of 3-acetyl coumarin inhibits Aβ peptide aggregation and protect against Aβ-induced cytotoxicity

(2016) Dnyanesh S. Ranade et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anti-Alzheimer's disease potential of coumarins from Angelica decursiva and Artemisia capillaris and structure-activity analysis

(2016) Md. Yousof Ali et al.   Asian Pacific Journal of Tropical Medicine

Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives

(2015) Maria João Matos et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Multifunctional coumarin derivatives: Monoamine oxidase B (MAO-B) inhibition, anti-β-amyloid (Aβ) aggregation and metal chelation properties against Alzheimer’s disease

(2015) Ming Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, cholinesterase inhibition and molecular modelling studies of coumarin linked thiourea derivatives

(2015) Aamer Saeed et al.   BIOORGANIC CHEMISTRY

Monoamine oxidase inhibitory activity of 2-aryl-4H-chromen-4-ones

(2015) Vishnu Nayak Badavath et al.   BIOORGANIC CHEMISTRY

Multi-target tacrine-coumarin hybrids: Cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease

(2015) Sai-Sai Xie et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New coumarin derivatives: Design, synthesis and use as inhibitors of hMAO

(2014) Xu He et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of aminoalkyl-substituted coumarin derivatives as acetylcholinesterase inhibitors

(2014) Seung Ok Nam et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and anti-cholinesterase activity of new 7-hydroxycoumarin derivatives

(2014) Masoumeh Alipour et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Some New 3-Coumaranone and Coumarin Derivatives as Dual Inhibitors of Acetyl- and Butyrylcholinesterase

(2013) Masoumeh Alipour et al.   ARCHIV DER PHARMAZIE

Phenylimino-2 H -chromen-3-carboxamide derivatives as novel small molecule inhibitors of β-secretase (BACE1)

(2013) Najmeh Edraki et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and evaluation of 4-substituted coumarins as novel acetylcholinesterase inhibitors

(2013) Seyyede Faeze Razavi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

(2013) Maria J. Matos et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, docking study and biological evaluation of some novel tetrahydrochromeno [3′,4′:5,6]pyrano[2,3-b]quinolin-6(7H)-one derivatives against acetyl- and butyrylcholinesterase

(2013) Mehdi Khoobi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel coumarin-3-carboxamides bearing N-benzylpiperidine moiety as potent acetylcholinesterase inhibitors

(2013) Ali Asadipour et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, biological evaluation and docking study of 5-oxo-4,5-dihydropyrano[3,2-c]chromene derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors

(2013) Mehdi Khoobi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fine molecular tuning at position 4 of 2H-chromen-2-one derivatives in the search of potent and selective monoamine oxidase B inhibitors

(2013) Leonardo Pisani et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and evaluation of novel tacrine–coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease

(2013) Sai-Sai Xie et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Potential anti-dengue medicinal plants: a review

(2013) Siti Latifah Abd Kadir et al.   Journal of Natural Medicines

Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl)-2-butenal in Tg2576 Alzheimer’s disease mice model

(2013) Peng Jin et al.   Journal of Neuroinflammation

Immunotherapy against amyloid pathology in Alzheimer's disease

(2013) Daniela Galimberti et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Novel coumarin derivatives bearing N-benzyl pyridinium moiety: Potent and dual binding site acetylcholinesterase inhibitors

(2012) Masoumeh Alipour et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase

(2012) Marco Catto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and evaluation of indanone derivatives as acetylcholinesterase inhibitors and metal-chelating agents

(2012) Fan-Chao Meng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Coumarins as Antioxidants

(2012) I. Kostova et al.   CURRENT MEDICINAL CHEMISTRY

Monoamine oxidase A and B inhibiting effect and molecular modeling of some synthesized coumarin derivatives

(2012) Omaima M. Abdelhafez et al.   NEUROCHEMISTRY INTERNATIONAL

A review on coumarins as acetylcholinesterase inhibitors for Alzheimer’s disease

(2011) Preet Anand et al.   BIOORGANIC & MEDICINAL CHEMISTRY

MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins

(2011) Maria João Matos et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery and synthesis of novel 3-phenylcoumarin derivatives as antidepressant agents

(2011) Koneni V. Sashidhara et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hydroxycoumarins as selective MAO-B inhibitors

(2011) Silvia Serra et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs

(2011) Salvatore Salomone et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer’s disease

(2011) B. Tasso et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives

(2011) Daniela Secci et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Study of a Series of 3-Arylcoumarins as Potent and Selective Monoamine Oxidase B Inhibitors

(2011) Maria J. Matos et al.   JOURNAL OF MEDICINAL CHEMISTRY

3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease

(2011) Dolores Viña et al.   MedChemComm

Synthesis and in vitro evaluation of novel coumarin–chalcone hybrids as potential anticancer agents

(2010) Koneni V. Sashidhara et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, Synthesis, and Biological Evaluation of Coumarin Derivatives Tethered to an Edrophonium-like Fragment as Highly Potent and Selective Dual Binding Site Acetylcholinesterase Inhibitors

(2010) Leonardo Pisani et al.   ChemMedChem

Antinociceptive and anti-inflammatory properties of 7-hydroxycoumarin in experimental animal models: potential therapeutic for the control of inflammatory chronic pain

(2010) Taís A. De Almeida Barros et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors

(2009) Maria Joao Matos et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effects of umbelliferone in a murine model of allergic airway inflammation

(2009) Juliana F. Vasconcelos et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Biological markers of amyloid β-related mechanisms in Alzheimer's disease

(2009) Harald Hampel et al.   EXPERIMENTAL NEUROLOGY

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Alzheimer's disease, metal ions and metal homeostatic therapy

(2009) Paolo Zatta et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties

(2008) Michael Decker et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and acetylcholinesterase inhibitory activity of novel coumarin analogues

(2008) Xiang Zhou et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inhibition of acetylcholinesterase by coumarins: The case of coumarin 106

(2008) A FALLARERO et al.   PHARMACOLOGICAL RESEARCH

Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds

(2007) Lorna Piazzi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness

(2006) Moussa B H Youdim et al.   BRITISH JOURNAL OF PHARMACOLOGY