On-the-Road Driving Performance the Morning after Bedtime Use of Suvorexant 20 and 40 mg: A Study in Non-Elderly Healthy Volunteers

Safety and efficacy of suvorexant during 1-year treatment of insomnia with subsequent abrupt treatment discontinuation: a phase 3 randomised, double-blind, placebo-controlled trial

(2014) David Michelson et al.   LANCET NEUROLOGY

Orexin receptor antagonists: a new treatment for insomnia?

(2014) Dieter Riemann et al.   LANCET NEUROLOGY

Alcohol calibration of tests measuring skills related to car driving

(2014) Stefan Jongen et al.   PSYCHOPHARMACOLOGY

The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold

(2013) Anthony L Gotter et al.   BMC NEUROSCIENCE

Zopiclone’s Residual Effects on Actual Driving Performance in a Standardized Test: A Pooled Analysis of Age and Sex Effects in 4 Placebo-Controlled Studies

(2013) Tim R.M. Leufkens et al.   CLINICAL THERAPEUTICS

Effects of prolonged-release melatonin and zolpidem on postural stability in older adults

(2012) Sarah Otmani et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Orexin receptor antagonism for treatment of insomnia: A randomized clinical trial of suvorexant

(2012) W. J. Herring et al.   NEUROLOGY

Blood drug concentrations of benzodiazepines correlate poorly with actual driving impairment

(2012) Joris C. Verster et al.   SLEEP MEDICINE REVIEWS

Effects of Benzodiazepines, Antidepressants and Opioids on Driving

(2011) Tharaka Dassanayake et al.   DRUG SAFETY

Promotion of Sleep by Suvorexant—A Novel Dual Orexin Receptor Antagonist

(2011) Christopher J. Winrow et al.   JOURNAL OF NEUROGENETICS

Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype

(2011) Johannes G. Ramaekers et al.   PSYCHOPHARMACOLOGY

Drivers can poorly predict their own driving impairment: a comparison between measurements of subjective and objective driving quality

(2011) Joris C. Verster et al.   PSYCHOPHARMACOLOGY

Next-Day Effects of Ramelteon (8 mg), Zopiclone (7.5 mg), and Placebo on Highway Driving Performance, Memory Functioning, Psychomotor Performance, and Mood in Healthy Adult Subjects

(2011) Monique A.J. Mets et al.   SLEEP

The Relationship between Benzodiazepine Use and Traffic Accidents

(2010) Beitske E. Smink et al.   CNS DRUGS

Discovery of the Dual Orexin Receptor Antagonist [(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia

(2010) Christopher D. Cox et al.   JOURNAL OF MEDICINAL CHEMISTRY

Highway Driving in the Elderly the Morning After Bedtime Use of Hypnotics

(2009) Tim R.M. Leufkens et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Highway driving performance and cognitive functioning the morning after bedtime and middle-of-the-night use of gaboxadol, zopiclone and zolpidem

(2009) TIM R. M. LEUFKENS et al.   JOURNAL OF SLEEP RESEARCH

The hyperarousal model of insomnia: A review of the concept and its evidence

(2009) Dieter Riemann et al.   SLEEP MEDICINE REVIEWS

Tolerability, pharmacokinetics and night-time effects on postural sway and critical flicker fusion of gaboxadol and zolpidem in elderly subjects

(2008) Julia Boyle et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY