Visualization of perforin/gasdermin/complement-formed pores in real cell membranes using atomic force microscopy

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Imaging modes of atomic force microscopy for application in molecular and cell biology

(2017) Yves F. Dufrêne et al.   Nature Nanotechnology

Combining confocal and atomic force microscopy to quantify single-virus binding to mammalian cell surfaces

(2017) Richard Newton et al.   Nature Protocols

HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis

(2016) Jacques J. Kessl et al.   CELL

Atomic force microscopy of membrane pore formation by cholesterol dependent cytolysins

(2016) Adrian W Hodel et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

(2016) Lorenzo Sborgi et al.   EMBO JOURNAL

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

RIPK1 inhibits ZBP1-driven necroptosis during development

(2016) Kim Newton et al.   NATURE

RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation

(2016) Juan Lin et al.   NATURE

Atomic force microscopy observation and characterization of single virions and virus-like particles by nano-indentation

(2016) M Marchetti et al.   Current Opinion in Virology

Nanoscale Surface Characterization of Human Erythrocytes by Atomic Force Microscopy: A Critical Review

(2015) Rashmi Mukherjee et al.   IEEE TRANSACTIONS ON NANOBIOSCIENCE

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Atomic structure of anthrax protective antigen pore elucidates toxin translocation

(2015) Jiansen Jiang et al.   NATURE

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Dividing Cells Regulate Their Lipid Composition and Localization

(2014) G. Ekin Atilla-Gokcumen et al.   CELL

Molecular Processes Studied at a Single-Molecule Level Using DNA Origami Nanostructures and Atomic Force Microscopy

(2014) Ilko Bald et al.   MOLECULES

Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin

(2014) Carl Leung et al.   eLife

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

(2013) J. A. Lopez et al.   BLOOD

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

(2013) Sohini Mukherjee et al.   NATURE

Atomic force microscopy probing in the measurement of cell mechanics

(2010) Dimitrios Kirmizis   International Journal of Nanomedicine

Conventional apoptosis assays using propidium iodide generate a significant number of false positives that prevent accurate assessment of cell death

(2010) Aja M. Rieger et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The structural basis for membrane binding and pore formation by lymphocyte perforin

(2010) Ruby H. P. Law et al.   NATURE

The Molecular Basis for Perforin Oligomerization and Transmembrane Pore Assembly

(2009) Katherine Baran et al.   IMMUNITY