Targeting NK-1 Receptors to Prevent and Treat Pancreatic Cancer: a New Therapeutic Approach

Population Attributable Risk for Pancreatic Cancer in Northern Italy

(2015) Valentina Rosato et al.   PANCREAS

Involvement of substance P and the NK-1 receptor in human pathology

(2014) Miguel Muñoz et al.   AMINO ACIDS

Chronic stress accelerates pancreatic cancer growth and invasion: A critical role for beta-adrenergic signaling in the pancreatic microenvironment

(2014) Corina Kim-Fuchs et al.   BRAIN BEHAVIOR AND IMMUNITY

Tachykinins and Their Receptors: Contributions to Physiological Control and the Mechanisms of Disease

(2014) Martin S. Steinhoff et al.   PHYSIOLOGICAL REVIEWS

Involvement of substance P and the NK-1 receptor in pancreatic cancer

(2014) Miguel Muñoz   WORLD JOURNAL OF GASTROENTEROLOGY

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Safety of neurokinin-1 receptor antagonists

(2013) Miguel Muñoz et al.   Expert Opinion On Drug Safety

Neurotransmitter Substance P Mediates Pancreatic Cancer Perineural Invasion via NK-1R in Cancer Cells

(2013) Xuqi Li et al.   MOLECULAR CANCER RESEARCH

Involvement of substance P and the NK-1 receptor in cancer progression

(2013) Miguel Muñoz et al.   PEPTIDES

Development of aprepitant, the first neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting

(2011) Richard Hargreaves et al.   Annals of the New York Academy of Sciences

Substance P immunoreactive nerve fibres are related to gastric cancer differentiation status and could promote proliferation and migration of gastric cancer cells

(2011) Fan Feng et al.   CELL BIOLOGY INTERNATIONAL

The NK-1 Receptor: A New Target in Cancer Therapy

(2011) Miguel Munoz et al.   CURRENT DRUG TARGETS

Targeting Opioid and Neurokinin-1 Receptors to Treat Alcoholism

(2011) F. D. Rodriguez et al.   CURRENT MEDICINAL CHEMISTRY

Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer

(2011) E. Gillespie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cigarette Smoke Synergizes Lipopolysaccharide-Induced InterIeukin-1β and Tumor Necrosis Factor–α Secretion from Macrophages via Substance P–Mediated Nuclear Factor–κB Activation

(2010) Junyang Xu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Targeting the Neurokinin Receptor 1 with Aprepitant: A Novel Antipruritic Strategy

(2010) Sonja Ständer et al.   PLoS One

Chronic stress sensitizes rats to pancreatitis induced by cerulein: Role of TNF-α

(2010) Marcelo G Binker   WORLD JOURNAL OF GASTROENTEROLOGY

The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug

(2009) Miguel Muñoz et al.   INVESTIGATIONAL NEW DRUGS

Neurokinin 1 Receptor Mediates Membrane Blebbing in HEK293 Cells through a Rho/Rho-associated Coiled-coil Kinase-dependent Mechanism

(2009) John Meshki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alcoholic Pancreatitis: Pathogenesis, Incidence and Treatment with Special Reference to the Associated Pain

(2009) Raffaele Pezzilli et al.   International Journal of Environmental Research and Public Health

Cell motility through plasma membrane blebbing

(2008) Oliver T. Fackler et al.   JOURNAL OF CELL BIOLOGY

A rat model reproducing key pathological responses of alcoholic chronic pancreatitis

(2007) Ilya Gukovsky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY