Hippocampal administration of chondroitinase ABC increases plaque-adjacent synaptic marker and diminishes amyloid burden in aged APPswe/PS1dE9 mice

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology

(2015) Sujeong Yang et al.   EXPERIMENTAL NEUROLOGY

Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease

(2015) Sophie Sokolow et al.   JOURNAL OF NEUROCHEMISTRY

Hippocampal plasticity during the progression of Alzheimer’s disease

(2015) E.J. Mufson et al.   NEUROSCIENCE

Hippocampal proteoglycans brevican and versican are linked to spatial memory of Sprague-Dawley rats in the morris water maze

(2014) Sivaprakasam R. Saroja et al.   JOURNAL OF NEUROCHEMISTRY

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

Aggrecan, link protein and tenascin-R are essential components of the perineuronal net to protect neurons against iron-induced oxidative stress

(2014) A Suttkus et al.   Cell Death & Disease

Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer’s disease mouse model

(2014) Wei Li et al.   Molecular Brain

Pathogenesis of Abeta Oligomers in Synaptic Failure

(2013) Senthilkumar Sivanesan et al.   Current Alzheimer Research

Depletion of Perineuronal Nets Enhances Recognition Memory and Long-Term Depression in the Perirhinal Cortex

(2013) C. Romberg et al.   JOURNAL OF NEUROSCIENCE

The synaptic plasticity and memory hypothesis: encoding, storage and persistence

(2013) T. Takeuchi et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Extracellular matrix inhibits structural and functional plasticity of dendritic spines in the adult visual cortex

(2013) L. de Vivo et al.   Nature Communications

Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer’s disease

(2012) Dávid Lendvai et al.   ACTA NEUROPATHOLOGICA

Brevican: A key proteoglycan in the perisynaptic extracellular matrix of the brain

(2012) Renato Frischknecht et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Lectican proteoglycans, their cleaving metalloproteinases, and plasticity in the central nervous system extracellular microenvironment

(2012) M.D. Howell et al.   NEUROSCIENCE

Selective Decline of Synaptic Protein Levels in the Frontal Cortex of Female Mice Deficient in the Extracellular Metalloproteinase ADAMTS1

(2012) Matthew D. Howell et al.   PLoS One

Involvement of Perineuronal and Perisynaptic Extracellular Matrix in Alzheimer's Disease Neuropathology

(2011) Markus Morawski et al.   BRAIN PATHOLOGY

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

Learning rules and persistence of dendritic spines

(2010) Haruo Kasai et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Modulation of Aβ42 fibrillogenesis by glycosaminoglycan structure

(2010) Juan José Valle-Delgado et al.   FASEB JOURNAL

Abnormal post-translational and extracellular processing of brevican in plaque-bearing mice over-expressing APPsw

(2010) Joanne M. Ajmo et al.   JOURNAL OF NEUROCHEMISTRY

Neurons associated with aggrecan-based perineuronal nets are protected against tau pathology in subcortical regions in Alzheimer's disease

(2010) M. Morawski et al.   NEUROSCIENCE

Influence of aging on chondroitin sulfate proteoglycan expression and neural stem/progenitor cells in rat brain and improving effects of a herbal medicine, yokukansan

(2009) Y. Tanaka et al.   NEUROSCIENCE

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perineuronal Nets Protect Fear Memories from Erasure

(2009) N. Gogolla et al.   SCIENCE

A role for the spine apparatus in LTP and spatial learning

(2008) Peter Jedlicka et al.   BEHAVIOURAL BRAIN RESEARCH

Multimodal signaling by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) promotes neurite extension

(2007) Michelle G. Hamel et al.   EXPERIMENTAL NEUROLOGY