Phosphorylation of serine/arginine-rich splicing factor 1 at tyrosine 19 promotes cell proliferation in pediatric acute lymphoblastic leukemia

Abstract 2374: Oncogenic kinases-induced PKM2 tyrosine 105 phosphorylation converts nononcogenic PKM2 to a tumor promoter and induces cancer stem-like cells

(2018) Lin Zhang et al.   CANCER RESEARCH

The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer

(2017) Thomas K. Sears et al.   Oncotarget

ZDHHC3 Tyrosine Phosphorylation Regulates Neural Cell Adhesion Molecule Palmitoylation

(2016) Patricia Marie-Jeanne Lievens et al.   MOLECULAR AND CELLULAR BIOLOGY

Tie2 Regulates Tumor Metastasis of Oral Squamous Cell Carcinomas

(2016) Daisuke Kitajima et al.   Journal of Cancer

Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

(2015) Ching-Hon Pui et al.   JOURNAL OF CLINICAL ONCOLOGY

SRSF1-Regulated Alternative Splicing in Breast Cancer

(2015) Olga Anczuków et al.   MOLECULAR CELL

Efficacy of Tie2 Receptor Antagonism in Angiosarcoma

(2015) Jason R. Hasenstein et al.   NEOPLASIA

Identification of a chemical inhibitor for nuclear speckle formation: Implications for the function of nuclear speckles in regulation of alternative pre-mRNA splicing

(2014) Yutaro Kurogi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Elevated CXCL1 expression in breast cancer stroma predicts poor prognosis and is inversely associated with expression of TGF-β signaling proteins

(2014) An Zou et al.   BMC CANCER

Overexpression of Chemokine (C-X-C) ligand 1 (CXCL1) associated with tumor progression and poor prognosis in hepatocellular carcinoma

(2014) Zhongwei Cao et al.   Cancer Cell International

A Phase I Study of Oral ARRY-614, a p38 MAPK/Tie2 Dual Inhibitor, in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes

(2014) G. Garcia-Manero et al.   CLINICAL CANCER RESEARCH

Emerging Functions of SRSF1, Splicing Factor and Oncoprotein, in RNA Metabolism and Cancer

(2014) S. Das et al.   MOLECULAR CANCER RESEARCH

Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells

(2014) V. Goncalves et al.   RNA

Clinical implications of AGBL2 expression and its inhibitor latexin in breast cancer

(2014) Hao Zhang et al.   World Journal of Surgical Oncology

RRM1 domain of the splicing oncoprotein SRSF1 is required for MEK1-MAPK-ERK activation and cellular transformation

(2013) Ariel Shimoni-Sebag et al.   CARCINOGENESIS

Correlation of SRSF1 and PRMT1 expression with clinical status of pediatric acute lymphoblastic leukemia

(2012) Limin Zou et al.   Journal of Hematology & Oncology

The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

(2012) Olga Anczuków et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Abnormal Expression of the Pre-mRNA Splicing Regulators SRSF1, SRSF2, SRPK1 and SRPK2 in Non Small Cell Lung Carcinoma

(2012) Stephanie Gout et al.   PLoS One

Regulation of Mcl-1 by SRSF1 and SRSF5 in Cancer Cells

(2012) Hannah L. Gautrey et al.   PLoS One

S6K1 Alternative Splicing Modulates Its Oncogenic Activity and Regulates mTORC1

(2012) Vered Ben-Hur et al.   Cell Reports

The Splicing Factor SRSF1 as a Marker for Endothelial Senescence

(2012) Francisco Javier Blanco et al.   Frontiers in Physiology

High bone marrow angiopoietin-1 expression is an independent poor prognostic factor for survival in patients with myelodysplastic syndromes

(2011) C-L Cheng et al.   BRITISH JOURNAL OF CANCER

Phosphorylation of SRSF1 is modulated by replicational stress

(2011) Valentina Leva et al.   NUCLEIC ACIDS RESEARCH

Identification of ASF/SF2 as a Critical, Allele-Specific Effector of the Cyclin D1b Oncogene

(2010) N. A. Olshavsky et al.   CANCER RESEARCH

Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a

(2010) J. C. Shultz et al.   CANCER RESEARCH

Quantifying oncogenic phosphotyrosine signaling networks through systems biology

(2010) Amanda M Del Rosario et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing

(2010) Rachel Wilson Goehe et al.   JOURNAL OF CLINICAL INVESTIGATION

Arginine Methylation Controls the Subcellular Localization and Functions of the Oncoprotein Splicing Factor SF2/ASF

(2010) Rahul Sinha et al.   MOLECULAR AND CELLULAR BIOLOGY

Pro-metastatic splicing of Ron proto-oncogene mRNA can be reversed: Therapeutic potential of bifunctional oligonucleotides and indole derivatives

(2010) Claudia Ghigna et al.   RNA Biology

A novel Physarum polycephalum SR protein kinase specifically phosphorylates the RS domain of the human SR protein, ASF/SF2

(2009) S. Liu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Allosteric Interactions Direct Binding and Phosphorylation of ASF/SF2 by SRPK1

(2009) Nhat Huynh et al.   BIOCHEMISTRY

Tyrosine phosphorylation: thirty years and counting

(2009) Tony Hunter   CURRENT OPINION IN CELL BIOLOGY

Kinase Domain Insertions Define Distinct Roles of CLK Kinases in SR Protein Phosphorylation

(2009) Alex N. Bullock et al.   STRUCTURE

Poly(ADP-ribose) Binds to the Splicing Factor ASF/SF2 and Regulates Its Phosphorylation by DNA Topoisomerase I

(2008) Maria Malanga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adaptable Molecular Interactions Guide Phosphorylation of the SR Protein ASF/SF2 by SRPK1

(2008) Jonathan C. Hagopian et al.   JOURNAL OF MOLECULAR BIOLOGY

The Splicing Factor SF2/ASF Regulates Translation Initiation by Enhancing Phosphorylation of 4E-BP1

(2008) Gracjan Michlewski et al.   MOLECULAR CELL

The splicing-factor oncoprotein SF2/ASF activates mTORC1

(2008) R. Karni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ordered Multi-site Phosphorylation of the Splicing Factor ASF/SF2 By SRPK1

(2007) Chen-Ting Ma et al.   JOURNAL OF MOLECULAR BIOLOGY