Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors

Published 2018 View Full Article

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Title
Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors
Authors
Keywords
KRAS, RAS-GTP, MAPK, cancer, CRAF, BRAF, MEK inhibitors, RAF inhibitors, PI3K inhibitors, combination treatment
Journal
CANCER CELL
Volume 34, Issue 4, Pages 611-625.e7
Publisher
Elsevier BV
Online
2018-10-09
DOI
10.1016/j.ccell.2018.09.002

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