Unique genomic profiles obtained from cerebrospinal fluid cell-free DNA of non-small cell lung cancer patients with leptomeningeal metastases

Unique genetic profiles from cerebrospinal fluid cell-free DNA in leptomeningeal metastases of EGFR-mutant non-small-cell lung cancer: a new medium of liquid biopsy

(2018) Y S Li et al.   ANNALS OF ONCOLOGY

Genetic profiling of cell-free DNA from cerebrospinal fluid: opening the barrier to leptomeningeal metastasis in EGFR-mutant NSCLC

(2018) I Vanden Bempt et al.   ANNALS OF ONCOLOGY

Leptin Stimulates Prolactin mRNA Expression in the Goldfish Pituitary through a Combination of the PI3K/Akt/mTOR, MKK3/6/p38MAPK and MEK1/2/ERK1/2 Signalling Pathways

(2017) Aifen Yan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

METCopy Number Gain Is Associated with Gefitinib Resistance in Leptomeningeal Carcinomatosis ofEGFR-mutant Lung Cancer

(2017) Shigeki Nanjo et al.   MOLECULAR CANCER THERAPEUTICS

Targeted treatment and immunotherapy in leptomeningeal metastases from melanoma

(2016) M. H. Geukes Foppen et al.   ANNALS OF ONCOLOGY

EGFR mutation status of paired cerebrospinal fluid and plasma samples in EGFR mutant non-small cell lung cancer with leptomeningeal metastases

(2016) Jing Zhao et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid

(2016) Elena I. Pentsova et al.   JOURNAL OF CLINICAL ONCOLOGY

Leptomeningeal Metastases in Patients with NSCLC with EGFR Mutations

(2016) Yang-Si Li et al.   Journal of Thoracic Oncology

EGFR mutation status on brain metastases from non-small cell lung cancer

(2016) Fred Hsu et al.   LUNG CANCER

Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy

(2016) C. Alix-Panabieres et al.   Cancer Discovery

Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies

(2015) Aurore Le Bescont et al.   ANTIOXIDANTS & REDOX SIGNALING

Brain Tumor Mutations Detected in Cerebral Spinal Fluid

(2015) W. Pan et al.   CLINICAL CHEMISTRY

Spatiotemporal T790M Heterogeneity in Individual Patients with EGFR-Mutant Non–Small-Cell Lung Cancer after Acquired Resistance to EGFR-TKI

(2015) Akito Hata et al.   Journal of Thoracic Oncology

Efficacy of the Irreversible ErbB Family Blocker Afatinib in Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI)–Pretreated Non–Small-Cell Lung Cancer Patients with Brain Metastases or Leptomeningeal Disease

(2015) Petra Hoffknecht et al.   Journal of Thoracic Oncology

Brain metastases in patients with EGFR -mutated or ALK -rearranged non-small-cell lung cancers

(2015) Deepa Rangachari et al.   LUNG CANCER

Treatment and survival of patients with EGFR -mutated non-small cell lung cancer and leptomeningeal metastasis: A retrospective cohort analysis

(2015) Justine L. Kuiper et al.   LUNG CANCER

Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma

(2015) Leticia De Mattos-Arruda et al.   Nature Communications

Sensitive Detection of EGFR Mutations in Cerebrospinal Fluid from Lung Adenocarcinoma Patients with Brain Metastases

(2014) Haihong Yang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice

(2014) H. J. Hartwell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Rebiopsy of non-small cell lung cancer patients with acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitor

(2013) Akito Hata et al.   CANCER

Analysis of Treatment Outcomes of Intraventricular Chemotherapy in 105 Patients for Leptomeningeal Carcinomatosis from Non–Small-Cell Lung Cancer

(2013) Ho-Shin Gwak et al.   Journal of Thoracic Oncology

Leptomeningeal Carcinomatosis in Non–Small-Cell Lung Cancer Patients: Impact on Survival and Correlated Prognostic Factors

(2013) Su Jin Lee et al.   Journal of Thoracic Oncology

Erlotinib Versus Gefitinib for Control of Leptomeningeal Carcinomatosis in Non–Small-Cell Lung Cancer

(2013) Eunyoung Lee et al.   Journal of Thoracic Oncology

Liquid biopsy: monitoring cancer-genetics in the blood

(2013) Emily Crowley et al.   Nature Reviews Clinical Oncology

Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells

(2011) Edita Aksamitiene et al.   CELLULAR SIGNALLING

Leptomeningeal Metastasis from Non-small Cell Lung Cancer: Survival and the Impact of Whole Brain Radiotherapy

(2011) Patrick G. Morris et al.   Journal of Thoracic Oncology

Met Activation in Non-Small Cell Lung Cancer Is Associated with de Novo Resistance to EGFR Inhibitors and the Development of Brain Metastasis

(2010) Elisa Benedettini et al.   AMERICAN JOURNAL OF PATHOLOGY

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS