Direct reprogramming of induced neural progenitors: a new promising strategy for AD treatment

Donepezil can improve daily activities and promote rehabilitation for severe Alzheimer’s patients in long-term care health facilities

(2014) Kenichi Meguro et al.   BMC Neurology

Generation of neural progenitor cells by chemical cocktails and hypoxia

(2014) Lin Cheng et al.   CELL RESEARCH

Disease-Modifying Anti-Alzheimer's Drugs: Inhibitors of Human Cholinesterases Interfering withβ-Amyloid Aggregation

(2014) Simone Brogi et al.   CNS Neuroscience & Therapeutics

A pilot randomized controlled trial evaluating an integrated treatment of rivastigmine transdermal patch and cognitive stimulation in patients with Alzheimer's disease

(2014) Grazia D'Onofrio et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

The Shanghai Aging Study: Study Design, Baseline Characteristics, and Prevalence of Dementia

(2014) Ding Ding et al.   NEUROEPIDEMIOLOGY

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Direct reprogramming of porcine fibroblasts to neural progenitor cells

(2014) Xiu-Ling Xu et al.   Protein & Cell

Tacrine-Flurbiprofen Hybrids as Multifunctional Drug Candidates for the Treatment of Alzheimer's Disease

(2013) Yao Chen et al.   ARCHIV DER PHARMAZIE

In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

(2013) Ziyuan Guo et al.   Cell Stem Cell

Memantine-sulfur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer’s disease

(2013) Piera Sozio et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway

(2013) Bing Gong et al.   MOLECULAR IMMUNOLOGY

In vivo reprogramming of astrocytes to neuroblasts in the adult brain

(2013) Wenze Niu et al.   NATURE CELL BIOLOGY

A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease

(2013) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Generation of induced neurons via direct conversion in vivo

(2013) O. Torper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental impact on direct neuronal reprogramming in vivo in the adult brain

(2013) Andrew Grande et al.   Nature Communications

2012 Alzheimer’s disease facts and figures

(2012)   Alzheimers & Dementia

Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

(2012) Karen L. Ring et al.   Cell Stem Cell

Direct Conversion of Dermal Fibroblasts into Neural Progenitor Cells by a Novel Cocktail of Defined Factors

(2012) C. Tian et al.   CURRENT MOLECULAR MEDICINE

Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction

(2012) Dongsun Park et al.   EXPERIMENTAL NEUROLOGY

Selective degeneration of septal and hippocampal GABAergic neurons in a mouse model of amyloidosis and tauopathy

(2012) Desirée Loreth et al.   NEUROBIOLOGY OF DISEASE

Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons

(2011) Samuele Marro et al.   Cell Stem Cell

Human Neural Stem Cells Overexpressing Choline Acetyltransferase Restore Cognitive Function of Kainic Acid-Induced Learning and Memory Deficit Animals

(2011) Dongsun Park et al.   CELL TRANSPLANTATION

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

(2011) W. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct conversion of human fibroblasts to dopaminergic neurons

(2011) U. Pfisterer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer's disease mouse model through modulation of neuroinflammation

(2010) Hyun Ju Lee et al.   NEUROBIOLOGY OF AGING

The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease

(2010) Hyun Ju Lee et al.   NEUROSCIENCE LETTERS

Modulation of Microglial Innate Immunity in Alzheimers Disease by Activation of Peroxisome Proliferator-activated Receptor Gamma

(2009) Feng-Shiun Shie et al.   CURRENT MEDICINAL CHEMISTRY

Transplantation of primed or unprimed mouse embryonic stem cell-derived neural precursor cells improves cognitive function in Alzheimerian rats

(2009) Farshad Homayouni Moghadam et al.   DIFFERENTIATION

Efficacy and safety of natural acetylcholinesterase inhibitor huperzine A in the treatment of Alzheimer’s disease: an updated meta-analysis

(2009) Bai-song Wang et al.   JOURNAL OF NEURAL TRANSMISSION

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

(2009) M. Blurton-Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient Processing of Alzheimer's Disease Amyloid-Beta Peptides by Neuroectodermally Converted Mesenchymal Stem Cells

(2009) Hans-Jörg Habisch et al.   STEM CELLS AND DEVELOPMENT

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

(2008) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

BDNF improves the effects of neural stem cells on the rat model of Alzheimer's disease with unilateral lesion of fimbria-fornix

(2008) A.G. Xuan et al.   NEUROSCIENCE LETTERS

Effects of engrafted neural stem cells in Alzheimer's disease rats

(2008) A.G. Xuan et al.   NEUROSCIENCE LETTERS

Bone marrow-derived mesenchymal stem cells reduce brain amyloid-β deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease mouse model

(2008) Jong Kil Lee et al.   NEUROSCIENCE LETTERS

Peripherally Administered Human Umbilical Cord Blood Cells Reduce Parenchymal and Vascular β-Amyloid Deposits in Alzheimer Mice

(2008) William V. Nikolic et al.   STEM CELLS AND DEVELOPMENT