Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway

Novel Immunoassay for Complement Activation by PF4/Heparin Complexes

(2018) Sanjay Khandelwal et al.   THROMBOSIS AND HAEMOSTASIS

The antigenic complex in HIT binds to B cells via complement and complement receptor 2 (CD21)

(2016) S. Khandelwal et al.   BLOOD

Further insights into the anti-PF4/heparin IgM immune response

(2016) Rabie Jouni et al.   THROMBOSIS AND HAEMOSTASIS

Critical role of CD4 T cells in PF4/heparin antibody production in mice

(2015) Y. Zheng et al.   BLOOD

Compstatin analog Cp40 inhibits complement dysregulation in vitro in C3 glomerulopathy

(2015) Yuzhou Zhang et al.   IMMUNOBIOLOGY

Natural IgM: Beneficial Autoantibodies for the Control of Inflammatory and Autoimmune Disease

(2014) Caroline Grönwall et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Anti-protamine-heparin antibodies: incidence, clinical relevance, and pathogenesis

(2013) T. Bakchoul et al.   BLOOD

High incidence of antibodies to protamine and protamine/heparin complexes in patients undergoing cardiopulmonary bypass

(2013) G. M. Lee et al.   BLOOD

Critical role for mouse marginal zone B cells in PF4/heparin antibody production

(2013) Y. Zheng et al.   BLOOD

B-cell tolerance regulates production of antibodies causing heparin-induced thrombocytopenia

(2013) Y. Zheng et al.   BLOOD

Incidence of antibodies to protamine sulfate/heparin complexes in cardiac surgery patients and impact on platelet activation and clinical outcome

(2013) Dorothée Leroux et al.   THROMBOSIS AND HAEMOSTASIS

Platelet factor 4 binding to lipid A of Gram-negative bacteria exposes PF4/heparin-like epitopes

(2012) K. Krauel et al.   BLOOD

Innate Immunity Mediates Follicular Transport of Particulate but Not Soluble Protein Antigen

(2012) A. Link et al.   JOURNAL OF IMMUNOLOGY

Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia

(2010) L. Rauova et al.   BLOOD

Platelet factor 4 binds to bacteria, inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia

(2010) K. Krauel et al.   BLOOD

Proteomic Profiling of a Layered Tissue Reveals Unique Glycolytic Specializations of Photoreceptor Cells

(2010) Boris Reidel et al.   MOLECULAR & CELLULAR PROTEOMICS

The human IgM pentamer is a mushroom-shaped molecule with a flexural bias

(2009) D. M. Czajkowsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of acetylated oligosaccharides by human L-ficolin

(2008) Anders Krarup et al.   IMMUNOLOGY LETTERS