Microbes, not humans: exploring the molecular basis of Pseudouridimycin selectivity towards bacterial and not human RNA polymerase

Dual Drug Targeting of Mutant Bcr-Abl Induces Inactive Conformation: New Strategy for the Treatment of Chronic Myeloid Leukemia and Overcoming Monotherapy Resistance

(2018) Ahmed A. El Rashedy et al.   CHEMISTRY & BIODIVERSITY

Co-inhibition as a strategic therapeutic approach to overcome rifampin resistance in tuberculosis therapy: atomistic insights

(2018) Clement Agoni et al.   Future Medicinal Chemistry

Application of Nanoparticle Technologies in the Combat against Anti-Microbial Resistance

(2018) et al.   Pharmaceutics

Tailored-pharmacophore model to enhance virtual screening and drug discovery: a case study on the identification of potential inhibitors against drug-resistant Mycobacterium tuberculosis (3R)-hydroxyacyl-ACP dehydratases

(2017) Kgothatso E Machaba et al.   Future Medicinal Chemistry

The antimicrobial activity of nanoparticles: present situation and prospects for the future

(2017) Linlin Wang et al.   International Journal of Nanomedicine

Advanced Prodrug Strategies in Nucleoside and Non-Nucleoside Antiviral Agents: A Review of the Recent Five Years

(2017) et al.   MOLECULES

Understanding and overcoming antibiotic resistance

(2017) Lauren A. Richardson   PLOS BIOLOGY

Antibiotic resistance

(2017) Marianne Frieri et al.   Journal of Infection and Public Health

Nanomaterials and molecular transporters to overcome the bacterial envelope barrier: Towards advanced delivery of antibiotics

(2017) Rita S. Santos et al.   ADVANCED DRUG DELIVERY REVIEWS

Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis

(2016) Erika A. Crane et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sliding Clamp of DNA Polymerase III as a Drug Target for TB Therapy: Comprehensive Conformational and Binding Analysis from Molecular Dynamic Simulations

(2016) Kgothatso E. Machaba et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Advances in the Pharmacogenomics of Adverse Drug Reactions

(2015) Susannah L. Collins et al.   DRUG SAFETY

X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein

(2015) Vadim Molodtsov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antibiotics in agriculture and the risk to human health: how worried should we be?

(2014) Qiuzhi Chang et al.   Evolutionary Applications

Evaluation of Anti-HIV-1 Mutagenic Nucleoside Analogues

(2014) Valérie Vivet-Boudou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

OriginPro 9.1: Scientific Data Analysis and Graphing Software—Software Review

(2014) E. Seifert   Journal of Chemical Information and Modeling

Prediction and Analysis of Surface Hydrophobic Residues in Tertiary Structure of Proteins

(2014) Shambhu Malleshappa Gowder et al.   TheScientificWorldJOURNAL

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

(2013) Daniel R. Roe et al.   Journal of Chemical Theory and Computation

Computer-Aided Drug Design Methodologies Toward the Design of Anti-Hepatitis C Agents

(2012) Alejandro Speck-Planche et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Rational Approaches to Improving Selectivity in Drug Design

(2012) David J. Huggins et al.   JOURNAL OF MEDICINAL CHEMISTRY

Avogadro: an advanced semantic chemical editor, visualization, and analysis platform

(2012) Marcus D Hanwell et al.   Journal of Cheminformatics

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Assessing the Performance of the MM/PBSA and MM/GBSA Methods. 1. The Accuracy of Binding Free Energy Calculations Based on Molecular Dynamics Simulations

(2010) Tingjun Hou et al.   Journal of Chemical Information and Modeling

Origins and Evolution of Antibiotic Resistance

(2010) J. Davies et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The RNA Polymerase “Switch Region” Is a Target for Inhibitors

(2008) Jayanta Mukhopadhyay et al.   CELL

New anti-tuberculosis drugs in clinical trials with novel mechanisms of action

(2008) Emma C. Rivers et al.   DRUG DISCOVERY TODAY