Synthesis of a heterotrifunctional linker for the site-specific preparation of antibody-drug conjugates with two distinct warheads

Published 2018 View Full Article

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Title
Synthesis of a heterotrifunctional linker for the site-specific preparation of antibody-drug conjugates with two distinct warheads
Authors
Keywords
Antibody−drug conjugates, Heterotrifunctional linkers, Monomethyl auristain E (MMAE), Pyrrolobenzodiazepine dimers (PBDs), Dual-warheads antibody-drug conjugates
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 28, Issue 23-24, Pages 3617-3621
Publisher
Elsevier BV
Online
2018-10-26
DOI
10.1016/j.bmcl.2018.10.043

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