Therapeutic strategies to target microbial protein–glycosaminoglycan interactions

Melittin and its potential in the destruction and inhibition of the biofilm formation by Staphylococcus aureus , Escherichia coli and Pseudomonas aeruginosa isolated from bovine milk

(2017) Tony Picoli et al.   MICROBIAL PATHOGENESIS

(−)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners

(2017) Tawanda Zininga et al.   MOLECULES

Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion

(2017) Xander M. van Wijk et al.   mBio

Vaginal Heparan Sulfate Linked to Neutrophil Dysfunction in the Acute Inflammatory Response Associated with Experimental Vulvovaginal Candidiasis

(2017) Junko Yano et al.   mBio

Dose-Dependent Induction of an Idiotypic Cascade by Anti-Glycosaminoglycan Monoclonal Antibody in apoE−/− Mice: Association with Atheroprotection

(2017) Roger Sarduy et al.   Frontiers in Immunology

Effects of sevuparin on rosette formation and cytoadherence of Plasmodium falciparum infected erythrocytes

(2017) Somporn Saiwaew et al.   PLoS One

A semi-synthetic glycosaminoglycan analogue inhibits and reverses Plasmodium falciparum cytoadherence

(2017) Mark A. Skidmore et al.   PLoS One

Inhibition of merozoite invasion and transient de-sequestration by sevuparin in humans with Plasmodium falciparum malaria

(2017) Anna M. Leitgeb et al.   PLoS One

Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation

(2017) Takuya Okada et al.   Scientific Reports

Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA

(2016) Manu Thomas Kalathottukaren et al.   BLOOD

Recent Updates on Development of Drug Molecules for Human African Trypanosomiasis

(2016) Ajmer Singh Grewal et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The toxicology of heparin reversal with protamine: past, present and future

(2016) Emilia Sokolowska et al.   Expert Opinion on Drug Metabolism & Toxicology

Glycosaminoglycans and infection

(2016) Pyong Woo Park   Frontiers in Bioscience-Landmark

Prognostic significance of highly sulfated chondroitin sulfates in ovarian cancer defined by the single chain antibody GD3A11

(2016) Sophieke C.H.A. van der Steen et al.   GYNECOLOGIC ONCOLOGY

Profiling the Membrane and Glycosaminoglycan-Binding Proteomes of Moraxella catarrhalis

(2016) Anita Karner et al.   JOURNAL OF PROTEOME RESEARCH

Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1

(2016) Marina Ayres Pereira et al.   PLoS Pathogens

Surface Proteoglycans as Mediators in Bacterial Pathogens Infections

(2016) Beatriz García et al.   Frontiers in Microbiology

Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth

(2015) Joji Iida et al.   EXPERIMENTAL CELL RESEARCH

Sugar-dependent modulation of neuronal development, regeneration, and plasticity by chondroitin sulfate proteoglycans

(2015) Gregory M. Miller et al.   EXPERIMENTAL NEUROLOGY

Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agents

(2015) Julio Valdivia-Silva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Leishmania chagasi heparin-binding protein: Cell localization and participation in L. chagasi infection

(2015) Thaís Viana Fialho Martins et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Differential Expression of Specific Dermatan Sulfate Domains in Renal Pathology

(2015) Joost F. M. Lensen et al.   PLoS One

Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages

(2015) Thomas Naderer et al.   PLoS Pathogens

Fucosylated Chondroitin Sulfate Inhibits Plasmodium falciparum Cytoadhesion and Merozoite Invasion

(2014) Marcele F. Bastos et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

DSTP-27 Prevents Entry of Human Cytomegalovirus

(2014) Rebekka Paeschke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel targeting using nanoparticles: an approach to the development of an effective anti-leishmanial drug-delivery system

(2014) Eduardo Coelho et al.   International Journal of Nanomedicine

An optimized nanoparticle delivery system based on chitosan and chondroitin sulfate molecules reduces the toxicity of amphotericin B and is effective in treating tegumentary leishmaniasis

(2014) Eduardo Coelho et al.   International Journal of Nanomedicine

A Small Molecule Inhibits Virion Attachment to Heparan Sulfate- or Sialic Acid-Containing Glycans

(2014) Che C. Colpitts et al.   JOURNAL OF VIROLOGY

Inactivation of Heparin by Cationically Modified Chitosan

(2014) Barbara Lorkowska-Zawicka et al.   Marine Drugs

The Novel Heparin-Binding Motif in Decorin-Binding Protein A from Strain B31 of Borrelia burgdorferi Explains the Higher Binding Affinity

(2013) Ashli Morgan et al.   BIOCHEMISTRY

Glycosaminoglycans in infectious disease

(2013) Eyal Kamhi et al.   BIOLOGICAL REVIEWS

Endosulfatases SULF1 and SULF2 limitChlamydia muridaruminfection

(2013) J. H. Kim et al.   CELLULAR MICROBIOLOGY

Heparin sensing and binding – taking supramolecular chemistry towards clinical applications

(2013) Stephen M. Bromfield et al.   CHEMICAL SOCIETY REVIEWS

The treatment with an anti-glycosaminoglycan antibody reduces aortic oxidative stress in a rabbit model of atherosclerosis

(2013) L. Delgado-Roche et al.   FREE RADICAL RESEARCH

Characterization of human placental glycosaminoglycans and regional binding to VAR2CSA in malaria infected erythrocytes

(2013) Julie M. Beaudet et al.   GLYCOCONJUGATE JOURNAL

Heparin-Binding Motifs and Biofilm Formation by Candida albicans

(2013) Julianne V. Green et al.   JOURNAL OF INFECTIOUS DISEASES

Effects of dextran sulfates on the acute infection and growth stages of Toxoplasma gondii

(2013) Akiko Ishiwa et al.   PARASITOLOGY RESEARCH

Carbohydrate-Related Inhibitors of Dengue Virus Entry

(2013) Kazuya Hidari et al.   Viruses-Basel

A Small Molecule Glycosaminoglycan Mimetic Blocks Plasmodium Invasion of the Mosquito Midgut

(2013) Derrick K. Mathias et al.   PLoS Pathogens

Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L

(2012) Tatiana F.R. Costa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea

(2012) J Steinmann et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of heparosan and heparin on the adhesion and biofilm formation of several bacteria in vitro

(2012) Xiang’e Chen et al.   CARBOHYDRATE POLYMERS

Toxoplasma gondii secretory proteins bind to sulfated heparin structures

(2012) N. Azzouz et al.   GLYCOBIOLOGY

Role of heparan sulfate in sexually transmitted infections

(2012) V. Tiwari et al.   GLYCOBIOLOGY

Structural and Functional Insight into How thePlasmodium falciparumVAR2CSA Protein Mediates Binding to Chondroitin Sulfate A in Placental Malaria

(2012) Thomas M. Clausen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Participation of heparin binding proteins from the surface of Leishmania (Viannia) braziliensis promastigotes in the adhesion of parasites to Lutzomyia longipalpis cells (Lulo) in vitro

(2012) Luzia de Castro Côrtes et al.   Parasites & Vectors

Comparative membrane proteome analysis of three Borrelia species

(2012) Bernd Gesslbauer et al.   PROTEOMICS

A role for heparan sulfate proteoglycans inPlasmodium falciparumsporozoite invasion of anopheline mosquito salivary glands

(2011) Jennifer S. Armistead et al.   BIOCHEMICAL JOURNAL

Fucoidan cures infection with both antimony-susceptible and -resistant strains of Leishmania donovani through Th1 response and macrophage-derived oxidants

(2011) S. Kar et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Anti-heparan Sulfate Peptides That Block Herpes Simplex Virus Infectionin Vivo

(2011) Vaibhav Tiwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of sulfated glycosaminoglycans on the development and attachment of Trypanosoma cruzi to the luminal midgut surface in the vector, Rhodnius prolixus

(2011) MARCELO S. GONZALEZ et al.   PARASITOLOGY

Evaluation of the Ability of LL-37 to Neutralise LPS In Vitro and Ex Vivo

(2011) Aaron Scott et al.   PLoS One

In Vivo Neutralization of Unfractionated Heparin and Low-Molecular-Weight Heparin by a Novel Salicylamide Derivative

(2010) Jacqueline Kuziej et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Proteoglycans in host–pathogen interactions: molecular mechanisms and therapeutic implications

(2010) Allison H. Bartlett et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Update on heparin: what do we need to know?

(2009) Daniel S. Weitz et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Cystic fibrosis

(2009) Brian P O'Sullivan et al.   LANCET

Sulfated K5 Escherichia coli polysaccharide derivatives: A novel class of candidate antiviral microbicides

(2009) Marco Rusnati et al.   PHARMACOLOGY & THERAPEUTICS

AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

(2009) Yuping Lai et al.   TRENDS IN IMMUNOLOGY

Melittin Interaction with Sulfated Cell Surface Sugars†

(2008) Gabriela Klocek et al.   BIOCHEMISTRY

Lack of Effectiveness of Cellulose Sulfate Gel for the Prevention of Vaginal HIV Transmission

(2008) Lut Van Damme et al.   NEW ENGLAND JOURNAL OF MEDICINE