The multifunctional role of phospho-calmodulin in pathophysiological processes

Ca 2+ signaling and Src-kinases-controlled cellular functions

(2018) Estefanía Anguita et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit

(2018) Guanqiao Wang et al.   BIOCHEMISTRY

Calmodulin as a protein linker and a regulator of adaptor/scaffold proteins

(2018) Antonio Villalobo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Protein phenotype diagnosis of autosomal dominant calmodulin mutations causing irregular heart rhythms

(2018) Noor A. Shaik et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures

(2018) Chia-Hsueh Lee et al.   SCIENCE

Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d

(2017) Satoshi Sogabe et al.   ACS Medicinal Chemistry Letters

Identification of initial leads directed at the calmodulin-binding region on the Src-SH2 domain that exhibit anti-proliferation activity against pancreatic cancer

(2016) Ywh-Min Tzou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel calmodulin mutations associated with congenital long QT syndrome affect calcium current in human cardiomyocytes

(2016) Daniel C. Pipilas et al.   HEART RHYTHM

The Arrhythmogenic Calmodulin Mutation D129G Dysregulates Cell Growth, Calmodulin-dependent Kinase II Activity, and Cardiac Function in Zebrafish

(2016) Martin W. Berchtold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane translocation of TRPC6 channels and endothelial migration are regulated by calmodulin and PI3 kinase activation

(2016) Pinaki Chaudhuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The activating role of phospho-(Tyr)-calmodulin on the epidermal growth factor receptor

(2015) S. R. Stateva et al.   BIOCHEMICAL JOURNAL

β-Adducin siRNA disruption of the spectrin-based cytoskeleton in differentiating keratinocytes prevented by calcium acting through calmodulin/epidermal growth factor receptor/cadherin pathway

(2015) Jianghong Wu et al.   CELLULAR SIGNALLING

Melatonin therapy for REM sleep behavior disorder: a critical review of evidence

(2015) Ian R. McGrane et al.   SLEEP MEDICINE

Ca2+/Calmodulin and Apo-Calmodulin Both Bind to and Enhance the Tyrosine Kinase Activity of c-Src

(2015) Silviya R. Stateva et al.   PLoS One

Characterization of Phospho-(Tyrosine)-Mimetic Calmodulin Mutants

(2015) Silviya R. Stateva et al.   PLoS One

Protein kinase CK2 contributes to diminished small conductance Ca2+-activated K+channel activity of hypothalamic pre-sympathetic neurons in hypertension

(2014) Judith Pachuau et al.   JOURNAL OF NEUROCHEMISTRY

Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology

(2014) Stefano Comai et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Selective phosphorylation modulates the PIP2 sensitivity of the CaM–SK channel complex

(2014) Miao Zhang et al.   Nature Chemical Biology

Arrhythmogenic Calmodulin Mutations Disrupt Intracellular Cardiomyocyte Ca 2+ Regulation by Distinct Mechanisms

(2014) Guo Yin et al.   Journal of the American Heart Association

The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer

(2013) Martin W. Berchtold et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Conformational Coupling across the Plasma Membrane in Activation of the EGF Receptor

(2013) Nicholas F. Endres et al.   CELL

Calmodulin Mutations Associated With Recurrent Cardiac Arrest in Infants

(2013) Lia Crotti et al.   CIRCULATION

Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design

(2013) Yanlong Zhao et al.   ACS Medicinal Chemistry Letters

Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation

(2012) Michael Piazza et al.   BIOCHEMISTRY

PTPRZ1 regulates calmodulin phosphorylation and tumor progression in small-cell lung carcinoma

(2012) Hideki Makinoshima et al.   BMC CANCER

Significance of Calcium Binding, Tyrosine Phosphorylation, and Lysine Trimethylation for the Essential Function of Calmodulin in Vertebrate Cells Analyzed in a Novel Gene Replacement System

(2012) Svetlana Panina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulating Uranium Binding Affinity in Engineered Calmodulin EF-Hand Peptides: Effect of Phosphorylation

(2012) Romain Pardoux et al.   PLoS One

Small-Conductance Ca2+-Activated K+ Channels: Form and Function

(2011) John P. Adelman et al.   Annual Review of Physiology

Oxidative Stress Causes Renal Angiotensin II Type 1 Receptor Upregulation, Na + /H + Exchanger 3 Overstimulation, and Hypertension

(2011) Anees A. Banday et al.   HYPERTENSION

Regulation of the Ligand-dependent Activation of the Epidermal Growth Factor Receptor by Calmodulin

(2011) Hongbing Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calmodulin Mediates Fas-induced FADD-independent Survival Signaling in Pancreatic Cancer Cells via Activation of Src-Extracellular Signal-regulated Kinase (ERK)

(2011) Kaiyu Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of CaM Kinase IV Activation During Hypoxia in Neuronal Nuclei of the Cerebral Cortex of Newborn Piglets: The Role of Src Kinase

(2011) Maria Delivoria-Papadopoulos et al.   NEUROCHEMICAL RESEARCH

Brain tissue energy dependence of CaM kinase IV cascade activation during hypoxia in the cerebral cortex of newborn piglets

(2011) Maria Delivoria-Papadopoulos et al.   NEUROSCIENCE LETTERS

Hypoxia-induced Activation of Epidermal Growth Factor Receptor (EGFR) Kinase in the Cerebral Cortex of Newborn Piglets: The Role of Nitric Oxide

(2010) Om Prakash Mishra et al.   NEUROCHEMICAL RESEARCH

Epidermal growth factor activates Na+/H+ exchanger in podocytes through a mechanism that involves Janus kinase and calmodulin

(2009) Sonya D. Coaxum et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Calmodulin-mediated regulation of the epidermal growth factor receptor

(2009) Pablo Sánchez-González et al.   FEBS Journal

Mechanism of Increased Tyrosine (Tyr99) Phosphorylation of Calmodulin During Hypoxia in the Cerebral Cortex of Newborn Piglets: The Role of nNOS-Derived Nitric Oxide

(2009) Om Prakash Mishra et al.   NEUROCHEMICAL RESEARCH

Biochemical characterization of CK2α and α′ paralogues and their derived holoenzymes: evidence for the existence of a heterotrimeric CK2α′-holoenzyme forming trimeric complexes

(2008) Birgitte B. Olsen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY