The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters

Evidence for a Molecular Diode-based Mechanism in a Multispecific ATP-binding cassette (ABC) Exporter

(2014) Jitender Mehla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generating Symmetry in the Asymmetric ATP-binding Cassette (ABC) Transporter Pdr5 fromSaccharomyces cerevisiae

(2014) Rakeshkumar P. Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter

(2014) M. Hohl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter

(2014) Nina Grossmann et al.   Nature Communications

Functional Impact of a Single Mutation within the Transmembrane Domain of the Multidrug ABC Transporter Pdr5

(2013) Petra Kueppers et al.   BIOCHEMISTRY

The Deviant ATP-binding Site of the Multidrug Efflux Pump Pdr5 Plays an Active Role in the Transport Cycle

(2013) Christopher Furman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational changes in the catalytically inactive nucleotide-binding site of CFTR

(2013) László Csanády et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mapping the functional yeast ABC transporter interactome

(2013) Jamie Snider et al.   Nature Chemical Biology

Multiple Transport-Active Binding Sites Are Available for a Single Substrate on Human P-Glycoprotein (ABCB1)

(2013) Eduardo E. Chufan et al.   PLoS One

Yeast ATP-Binding Cassette Transporters Conferring Multidrug Resistance

(2012) Rajendra Prasad et al.   Annual Review of Microbiology

The Transmission Interface of the Saccharomyces cerevisiae Multidrug Transporter Pdr5: Val-656 Located in Intracellular Loop 2 Plays a Major Role in Drug Resistance

(2012) M. T. Downes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A conserved interdomain communication pathway of pseudosymmetrically distributed residues affects substrate specificity of the fungal multidrug transporter Cdr1p

(2012) Marcin Kolaczkowski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

(2012) Mi Sun Jin et al.   NATURE

The Signaling Interface of the Yeast Multidrug Transporter Pdr5 Adopts a Cis Conformation, and There Are Functional Overlap and Equivalence of the Deviant and Canonical Q-Loop Residues

(2010) Neeti Ananthaswamy et al.   BIOCHEMISTRY

Optimization of the Degenerated Interfacial ATP Binding Site Improves the Function of Disease-related Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channels

(2010) Ming-Feng Tsai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel

(2010) Ming-Feng Tsai et al.   JOURNAL OF GENERAL PHYSIOLOGY

Toward understanding the mechanism of action of the yeast multidrug resistance transporter Pdr5p: A molecular modeling study

(2010) Robert M. Rutledge et al.   JOURNAL OF STRUCTURAL BIOLOGY

The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport

(2009) Nidhi Puri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter

(2009) Erik Procko et al.   FASEB JOURNAL

Structural arrangement of the transmission interface in the antigen ABC transport complex TAP

(2009) G. Oancea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Functional Clustering of Mutations in the Dimer Interface of the Nucleotide Binding Folds of the Sulfonylurea Receptor

(2008) Ricard Masia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations Define Cross-talk between the N-terminal Nucleotide-binding Domain and Transmembrane Helix-2 of the Yeast Multidrug Transporter Pdr5

(2008) Zuben E. Sauna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5

(2008) Robert Ernst et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The High-Affinity E. coli Methionine ABC Transporter: Structure and Allosteric Regulation

(2008) N. S. Kadaba et al.   SCIENCE