Furo[3,2-b ]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Furo[3,2-b
]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway
Authors
Keywords
-
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 58, Issue 4, Pages 1062-1066
Publisher
Wiley
Online
2018-12-20
DOI
10.1002/anie.201810312
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Downregulation of dual-specificity tyrosine-regulated kinase 2 promotes tumor cell proliferation and invasion by enhancing cyclin-dependent kinase 14 expression in breast cancer
- (2018) Yoshimi Imawari et al. CANCER SCIENCE
- Kinase inhibitors: the road ahead
- (2018) Fleur M. Ferguson et al. NATURE REVIEWS DRUG DISCOVERY
- An insight on synthetic and medicinal aspects of pyrazolo[1,5- a ]pyrimidine scaffold
- (2017) Srinivasulu Cherukupalli et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma
- (2017) Qingqing Zhou et al. JOURNAL OF MEDICINAL CHEMISTRY
- Regulation of DNA replication proteins in parasitic protozoans: possible role of CDK-like kinases
- (2016) Abhijit S. Deshmukh et al. CURRENT GENETICS
- An ID2-dependent mechanism for VHL inactivation in cancer
- (2016) Sang Bae Lee et al. NATURE
- CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer
- (2015) T. Yoshida et al. CANCER RESEARCH
- Elaboration of Furopyridine Scaffolds
- (2015) Adeline Jasselin-Hinschberger et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Privileged scaffolds in lead generation
- (2015) Hongyu Zhao et al. Expert Opinion on Drug Discovery
- Detained introns are a novel, widespread class of post-transcriptionally spliced introns
- (2015) Paul L. Boutz et al. GENES & DEVELOPMENT
- Comprehensive characterization of the Published Kinase Inhibitor Set
- (2015) Jonathan M Elkins et al. NATURE BIOTECHNOLOGY
- A historical overview of protein kinases and their targeted small molecule inhibitors
- (2015) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Human CDC2-Like Kinase 1 (CLK1): A Novel Target for Alzheimer’s Disease
- (2014) Princi Jain et al. CURRENT DRUG TARGETS
- 1,3,5-Triazine-based analogues of purine: From isosteres to privileged scaffolds in medicinal chemistry
- (2014) Felicia Phei Lin Lim et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Dual kinase-bromodomain inhibitors for rationally designed polypharmacology
- (2014) Pietro Ciceri et al. Nature Chemical Biology
- Discovery of pyrazolo[1,5-a]pyrimidine-based Pim inhibitors: A template-based approach
- (2013) Michael P. Dwyer et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The mechanisms of Hedgehog signalling and its roles in development and disease
- (2013) James Briscoe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Benzofurans from Benzophenones and Dimethylacetamide: Copper-Promoted Cascade Formation of Furan O1C2 and C2C3 Bonds Under Oxidative Conditions
- (2012) María J. Moure et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cyclin-dependent kinase Inhibitors Inspired by Roscovitine: Purine Bioisosteres
- (2012) Radek Jorda et al. CURRENT PHARMACEUTICAL DESIGN
- A public-private partnership to unlock the untargeted kinome
- (2012) Stefan Knapp et al. Nature Chemical Biology
- Small-Molecule Inhibitors of the Hedgehog Signaling Pathway as Cancer Therapeutics
- (2010) Stefan Peukert et al. ChemMedChem
- Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk)
- (2009) Bryan T. Mott et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation
- (2009) Yu Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Furo[3,2-b]pyridine: a convenient unit for the synthesis of polyheterocycles
- (2008) Anthony Chartoire et al. TETRAHEDRON
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started