Filamin-A as a Balance between Erk/Smad Activities During Cardiac Valve Development

Mutations in DCHS1 cause mitral valve prolapse

(2015) Ronen Durst et al.   NATURE

Periostin Induces Intracellular Cross-talk between Kinases and Hyaluronan in Atrioventricular Valvulogenesis

(2014) Shibnath Ghatak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel no-stop FLNA mutation causes multi-organ involvement in males

(2013) Renske Oegema et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Valvular dystrophy associated filamin A mutations reveal a new role of its first repeats in small-GTPase regulation

(2013) D. Duval et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Valvular heart disease: a call for global collaborative research initiatives

(2013) John B Chambers et al.   HEART

Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders

(2013) Marcel den Hoed et al.   NATURE GENETICS

Developmental basis for filamin-A-associated myxomatous mitral valve disease

(2012) Kimberly Sauls et al.   CARDIOVASCULAR RESEARCH

Atrioventricular valve development: New perspectives on an old theme

(2012) Annemarieke de Vlaming et al.   DIFFERENTIATION

Congenital short bowel syndrome as the presenting symptom in male patients with FLNA mutations

(2012) Christine S. van der Werf et al.   GENETICS IN MEDICINE

Filamin-A-Related Myxomatous Mitral Valve Dystrophy: Genetic, Echocardiographic and Functional Aspects

(2011) Aurélie Lardeux et al.   Journal of Cardiovascular Translational Research

Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis

(2010) R.A. Norris et al.   DEVELOPMENTAL DYNAMICS

Regulation of cell adhesion to collagen via β1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon

(2010) Hugh Kim et al.   EXPERIMENTAL CELL RESEARCH

Valvular heart disease: the next cardiac epidemic

(2010) J. L. d'Arcy et al.   HEART

R-Ras interacts with filamin a to maintain endothelial barrier function

(2010) G.S. Griffiths et al.   JOURNAL OF CELLULAR PHYSIOLOGY

R-Ras Regulates Migration through an Interaction with Filamin A in Melanoma Cells

(2010) Joanna E. Gawecka et al.   PLoS One

Filamins in cell signaling, transcription and organ development

(2010) Alex-Xianghua Zhou et al.   TRENDS IN CELL BIOLOGY

Phosphorylation Facilitates the Integrin Binding of Filamin under Force

(2009) Harvey S. Chen et al.   BIOPHYSICAL JOURNAL

Filamin A–β1 Integrin Complex Tunes Epithelial Cell Response to Matrix Tension

(2009) Scott Gehler et al.   MOLECULAR BIOLOGY OF THE CELL

Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease

(2008) Rajeev Mahimkar et al.   CARDIOVASCULAR PATHOLOGY

Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome

(2008) M. Krenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Outcomes in Mitral Regurgitation Due to Flail Leaflets

(2008) Francesco Grigioni et al.   JACC-Cardiovascular Imaging