Prenatal hypoxia impairs cardiac mitochondrial and ventricular function in guinea pig offspring in a sex-related manner

IUGR decreases cardiomyocyte endowment and alters cardiac metabolism in a sex- and cause-of-IUGR-specific manner

(2018) K. J. Botting et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Intermittent hypoxia in utero damages postnatal growth and cardiovascular function in rats

(2018) Ling Chen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic

(2018) Janna L. Morrison et al.   JOURNAL OF PHYSIOLOGY-LONDON

Maternal treatment with a placental-targeted antioxidant (MitoQ) impacts offspring cardiovascular function in a rat model of prenatal hypoxia

(2018) Mais M. Aljunaidy et al.   PHARMACOLOGICAL RESEARCH

Sexual dimorphism of mitochondrial function in the hypoxic guinea pig placenta†

(2018) Hong Song et al.   BIOLOGY OF REPRODUCTION

Estrogens regulate life and death in mitochondria

(2017) Carolyn M. Klinge   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

The highs and lows of programmed cardiovascular disease by developmental hypoxia: studies in the chicken embryo

(2017) N. Itani et al.   JOURNAL OF PHYSIOLOGY-LONDON

Maternal nutrient restriction in guinea pigs leads to fetal growth restriction with evidence for chronic hypoxia

(2017) Alexander A Elias et al.   PEDIATRIC RESEARCH

Hypoxia: From Placental Development to Fetal Programming

(2017) Lais Fajersztajn et al.   Birth Defects Research

Prenatal hypoxia leads to hypertension, renal renin-angiotensin system activation and exacerbates salt-induced pathology in a sex-specific manner

(2017) S. L. Walton et al.   Scientific Reports

PRKCE gene encoding protein kinase C-epsilon—Dual roles at sarcomeres and mitochondria in cardiomyocytes

(2016) Sarah B. Scruggs et al.   GENE

Developmental Programming of Hypertension

(2016) John Henry Dasinger et al.   HYPERTENSION

Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging

(2016) Sherif F. Nagueh et al.   JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

A review of fundamental principles for animal models of DOHaD research: an Australian perspective

(2016) H. Dickinson et al.   Journal of Developmental Origins of Health and Disease

Successful implantation of an abdominal aortic blood pressure transducer and radio-telemetry transmitter in guinea pigs — Anaesthesia, analgesic management and surgical methods, and their influence on hemodynamic parameters and body temperature

(2016) Sabrina Schmitz et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Impact of chronic hypoxemia on blood flow to the brain, heart, and adrenal gland in the late-gestation IUGR sheep fetus

(2015) Rajan Poudel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Animal models of fetal growth restriction: Considerations for translational medicine

(2015) A.M. Swanson et al.   PLACENTA

Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging

(2015) Roberto M. Lang et al.   European Heart Journal-Cardiovascular Imaging

Maternal Nutrient Restriction Alters Ca2+ Handling Properties and Contractile Function of Isolated Left Ventricle Bundles in Male But Not Female Juvenile Rats

(2015) Thomas J. Harvey et al.   PLoS One

Prenatal Hypoxia Leads to Increased Muscle Sympathetic Nerve Activity, Sympathetic Hyperinnervation, Premature Blunting of Neuropeptide Y Signaling, and Hypertension in Adult Life

(2014) William Rook et al.   HYPERTENSION

Prenatal Hypoxia Reduces Mitochondrial Protein Levels and Cytochrome c Oxidase Activity in Offspring Guinea Pig Hearts

(2014) Yazan M. Al-Hasan et al.   Reproductive Sciences

Chronic Hypoxemia in Late Gestation Decreases Cardiomyocyte Number but Does Not Change Expression of Hypoxia‐Responsive Genes

(2014) Kimberley J. Botting et al.   Journal of the American Heart Association

Prenatal hypoxia programs changes in β-adrenergic signaling and postnatal cardiac contractile dysfunction

(2013) I. Lindgren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Vitamin C Prevents Intrauterine Programming of in vivo Cardiovascular Dysfunction in the Rat

(2013) Andrew D. Kane et al.   CIRCULATION JOURNAL

Prenatal Hypoxia Causes Long-Term Alterations in Vascular Endothelin-1 Function in Aged Male, but Not Female, Offspring

(2013) Stephane L. Bourque et al.   HYPERTENSION

Developmental programming of cardiovascular disease by prenatal hypoxia

(2013) D. A. Giussani et al.   Journal of Developmental Origins of Health and Disease

Metabolic adaptation to chronic hypoxia in cardiac mitochondria

(2012) Lisa C. Heather et al.   BASIC RESEARCH IN CARDIOLOGY

Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells

(2012) Marco Spinazzi et al.   Nature Protocols

Chronic hypoxia increases peroxynitrite, MMP9 expression and collagen accumulation in fetal guinea pig hearts

(2012) LaShauna C. Evans et al.   PEDIATRIC RESEARCH

Standardized bioenergetic profiling of adult mouse cardiomyocytes

(2012) Ryan D. Readnower et al.   PHYSIOLOGICAL GENOMICS

Developmental Programming of Cardiovascular Dysfunction by Prenatal Hypoxia and Oxidative Stress

(2012) Dino A. Giussani et al.   PLoS One

Chronic Hypoxia Impairs Cytochrome Oxidase Activity Via Oxidative Stress in Selected Fetal Guinea Pig Organs

(2012) Yazan M. Al-Hasan et al.   Reproductive Sciences

Effects of hypoxia-induced intrauterine growth restriction on cardiac siderosis and oxidative stress

(2012) C. F. Rueda-Clausen et al.   Journal of Developmental Origins of Health and Disease

Maternal hypoxia alters matrix metalloproteinase expression patterns and causes cardiac remodeling in fetal and neonatal rats

(2011) Wenni Tong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypoxia-derived oxidative stress mediates epigenetic repression of PKCɛ gene in foetal rat hearts

(2011) Andrew J. Patterson et al.   CARDIOVASCULAR RESEARCH

Long-term effects of intrauterine growth restriction on cardiac metabolism and susceptibility to ischaemia/reperfusion

(2010) Christian F. Rueda-Clausen et al.   CARDIOVASCULAR RESEARCH

Chronic Prenatal Hypoxia Induces Epigenetic Programming of PKCε Gene Repression in Rat Hearts

(2010) Andrew J. Patterson et al.   CIRCULATION RESEARCH

The Na+/Ca2+ exchanger-1 mediates left ventricular dysfunction in mice with chronic intermittent hypoxia

(2010) Ling Chen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Developmental programming and hypertension

(2009) Anne Monique Nuyt et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Gender Differences in Cardiac Ischemic Injury and Protection—Experimental Aspects

(2009) Bohuslav Ostadal et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Prenatal Hypoxia Causes a Sex-Dependent Increase in Heart Susceptibility to Ischemia and Reperfusion Injury in Adult Male Offspring: Role of Protein Kinase C 

(2009) Q. Xue et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Chronic Hypoxia Increases Inducible NOS-Derived Nitric Oxide in Fetal Guinea Pig Hearts

(2009) Loren Thompson et al.   PEDIATRIC RESEARCH

Intrauterine hypoxia upregulates proinflammatory cytokines and matrix metalloproteinases in fetal guinea pig hearts

(2008) Chien Oh et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Effects of hypoxia-induced intrauterine growth restriction on cardiopulmonary structure and function during adulthood

(2008) Christian F. Rueda-Clausen et al.   CARDIOVASCULAR RESEARCH

SHEEP MODELS OF INTRAUTERINE GROWTH RESTRICTION: FETAL ADAPTATIONS AND CONSEQUENCES

(2008) Janna L Morrison   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Effect of In Utero and Early-Life Conditions on Adult Health and Disease

(2008) Peter D. Gluckman et al.   NEW ENGLAND JOURNAL OF MEDICINE