Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis

Approaching a Scientific Consensus on the Association between Allergies and Glioma Risk: A Report from the Glioma International Case-Control Study

(2016) E. S. Amirian et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease

(2016) Sylwia Smolinska et al.   INFLAMMATORY BOWEL DISEASES

Novel function of histamine signaling via histamine receptors in cholesterol and bile acid metabolism: Histamine H2 receptor protects against nonalcoholic fatty liver disease

(2016) Sohsuke Yamada et al.   PATHOLOGY INTERNATIONAL

Histamine H2 Receptor-Mediated Suppression of Intestinal Inflammation by Probiotic Lactobacillus reuteri

(2015) Chunxu Gao et al.   mBio

PROGgeneV2: enhancements on the existing database

(2015) Chirayu Pankaj Goswami et al.   BMC CANCER

Integrative genomic analyses of the histamine H1 receptor and its role in cancer prediction

(2014) MINGHAI WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Histamine and gut mucosal immune regulation

(2013) S. Smolinska et al.   ALLERGY

Histamine receptor 2 modifies dendritic cell responses to microbial ligands

(2013) Remo Frei et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Drugs that inhibit gastric acid secretion may alter the course of inflammatory bowel disease

(2012) P. Juillerat et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Mast cells and IgE activation do not alter the development of oral tolerance in a murine model

(2012) Matthew C. Tunis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Histamine regulation of biliary proliferation

(2012) Heather Francis et al.   JOURNAL OF HEPATOLOGY

Histamine Derived from Probiotic Lactobacillus reuteri Suppresses TNF via Modulation of PKA and ERK Signaling

(2012) Carissa M. Thomas et al.   PLoS One

Cotreatment with dichloroacetate and omeprazole exhibits a synergistic antiproliferative effect on malignant tumors

(2012) TATSUAKI ISHIGURO et al.   Oncology Letters

Intestinal Inflammation and Cancer

(2011) Thomas A. Ullman et al.   GASTROENTEROLOGY

Inhibition of histidine decarboxylase ablates the autocrine tumorigenic effects of histamine in human cholangiocarcinoma

(2011) Heather Francis et al.   GUT

Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells

(2010) D Mahalingam et al.   BRITISH JOURNAL OF CANCER

An apple oligogalactan prevents against inflammation and carcinogenesis by targeting LPS/TLR4/NF- B pathway in a mouse model of colitis-associated colon cancer

(2010) L. Liu et al.   CARCINOGENESIS

MAP kinases in inflammatory bowel disease

(2010) Mehmet Coskun et al.   CLINICA CHIMICA ACTA

Plasma histamine levels (H) during adjunctive H1-receptor antagonist treatment with loratadine in patients with active Inflammatory Bowel disease (IBD)

(2010) M. Raithel et al.   INFLAMMATION RESEARCH

An innately dangerous balancing act: intestinal homeostasis, inflammation, and colitis-associated cancer: Figure 1.

(2010) Mark Asquith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ERK activation drives intestinal tumorigenesis in Apcmin/+ mice

(2010) Sung Hee Lee et al.   NATURE MEDICINE

Histamine deficiency promotes inflammation-associated carcinogenesis through reduced myeloid maturation and accumulation of CD11b+Ly6G+ immature myeloid cells

(2010) Xiang Dong Yang et al.   NATURE MEDICINE

The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

(2010) E. W. Joseph et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

p38α blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1α- to FoxO-dependent transcription

(2009) F Chiacchiera et al.   CELL DEATH AND DIFFERENTIATION

The histamine H3 receptor as a therapeutic drug target for CNS disorders

(2009) Mark J. Gemkow et al.   DRUG DISCOVERY TODAY

Histamine Induces Egr-1 Expression in Human Aortic Endothelial Cells via the H1 Receptor-mediated Protein Kinase Cδ-dependent ERK Activation Pathway

(2008) Feng Hao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB in inflammatory bowel disease

(2008) I. Atreya et al.   JOURNAL OF INTERNAL MEDICINE

The Influence of Mast Cell Mediators on Migration of SW756 Cervical Carcinoma Cells

(2008) M. Isolde Rudolph et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines

(2008) Robin L. Thurmond et al.   NATURE REVIEWS DRUG DISCOVERY