Modulating GLUT1 expression in retinal pigment epithelium decreases glucose levels in the retina: impact on photoreceptors and Müller glial cells

A journey into the retina: Müller glia commanding survival and death

(2018) Paula V. Subirada et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Deletion of GLUT1 in mouse lens epithelium leads to cataract formation

(2018) Aditi Swarup et al.   EXPERIMENTAL EYE RESEARCH

Impact of euthanasia, dissection and postmortem delay on metabolic profile in mouse retina and RPE/choroid

(2018) Siyan Zhu et al.   EXPERIMENTAL EYE RESEARCH

Cadherins in the retinal pigment epithelium (RPE) revisited: P-cadherin is the highly dominant cadherin expressed in human and mouse RPE in vivo

(2018) Xue Yang et al.   PLoS One

Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

(2018) Ammaji Rajala et al.   Cell Death & Disease

Pyruvate kinase M2 isoform deletion in cone photoreceptors results in age-related cone degeneration

(2018) Ammaji Rajala et al.   Cell Death & Disease

Aerobic Glycolysis Is Essential for Normal Rod Function and Controls Secondary Cone Death in Retinitis Pigmentosa

(2018) Lolita Petit et al.   Cell Reports

SNAT3-mediated glutamine transport in perisynaptic astrocytes in situ is regulated by intracellular sodium

(2017) Alison C. Todd et al.   GLIA

The retinal pigmented epithelium – from basic developmental biology research to translational approaches

(2017) Benjamin Amram et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Phagocytosis-dependent ketogenesis in retinal pigment epithelium

(2017) Juan Reyes-Reveles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AIM2 Engages Active but Unprocessed Caspase-1 to Induce Noncanonical Activation of the NLRP3 Inflammasome

(2017) Larissa D. Cunha et al.   Cell Reports

Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye

(2017) Mark A Kanow et al.   eLife

Glycolytic reliance promotes anabolism in photoreceptors

(2017) Yashodhan Chinchore et al.   eLife

An easy, rapid method to isolate RPE cell protein from the mouse eye

(2016) Hong Wei et al.   EXPERIMENTAL EYE RESEARCH

NRL-Regulated Transcriptome Dynamics of Developing Rod Photoreceptors

(2016) Jung-Woong Kim et al.   Cell Reports

Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration

(2016) Toshihide Kurihara et al.   eLife

Disruption of murineAdamtsl4results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation

(2015) Gayle B. Collin et al.   HUMAN MOLECULAR GENETICS

Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina

(2015) Jianhai Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in CTNNA1 cause butterfly-shaped pigment dystrophy and perturbed retinal pigment epithelium integrity

(2015) Nicole T M Saksens et al.   NATURE GENETICS

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

(2015) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Loss of function mutation of the Slc38a3 glutamine transporter reveals its critical role for amino acid metabolism in the liver, brain, and kidney

(2015) Kessara Chan et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Plasma membrane protein polarity and trafficking in RPE cells: Past, present and future

(2014) Guillermo L. Lehmann et al.   EXPERIMENTAL EYE RESEARCH

Cultured primary human fetal retinal pigment epithelium (hfRPE) as a model for evaluating RPE metabolism

(2014) Jeffrey Adijanto et al.   EXPERIMENTAL EYE RESEARCH

The Retinal Pigment Epithelium Utilizes Fatty Acids for Ketogenesis

(2014) Jeffrey Adijanto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeted deletion of Vegfa in adult mice induces vision loss

(2012) Toshihide Kurihara et al.   JOURNAL OF CLINICAL INVESTIGATION

Blood-Retinal Barrier

(2010) José Cunha-Vaz et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

Facilitative glucose transporter Glut1 is actively excluded from rod outer segments

(2010) S. M. Gospe et al.   JOURNAL OF CELL SCIENCE

mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice

(2010) Chen Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Light-Evoked Responses of the Retinal Pigment Epithelium: Changes Accompanying Photoreceptor Loss in the Mouse

(2010) Ivy S. Samuels et al.   JOURNAL OF NEUROPHYSIOLOGY

The Tight Junction Associated Signalling Proteins ZO-1 and ZONAB Regulate Retinal Pigment Epithelium Homeostasis in Mice

(2010) Anastasios Georgiadis et al.   PLoS One

The multifunctional choroid

(2009) Debora L. Nickla et al.   PROGRESS IN RETINAL AND EYE RESEARCH

The transcriptome of retinal Müller glial cells

(2008) Karin Roesch et al.   JOURNAL OF COMPARATIVE NEUROLOGY