GPR126 : A novel candidate gene implicated in autosomal recessive intellectual disability

Biallelic variants in LINGO1 are associated with autosomal recessive intellectual disability, microcephaly, speech and motor delay

(2017) Muhammad Ansar et al.   GENETICS IN MEDICINE

Activation of Adhesion G Protein-coupled Receptors

(2017) Lilian M. Demberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination

(2017) Monica Ghidinelli et al.   PLOS BIOLOGY

Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair

(2016) Amit Mogha et al.   JOURNAL OF NEUROSCIENCE

Adhesion G protein-coupled receptors in nervous system development and disease

(2016) Tobias Langenhan et al.   NATURE REVIEWS NEUROSCIENCE

Mutations of GPR126 Are Responsible for Severe Arthrogryposis Multiplex Congenita

(2015) Gianina Ravenscroft et al.   AMERICAN JOURNAL OF HUMAN GENETICS

LAMA2-related congenital muscular dystrophy complicated by West syndrome

(2015) Ana Camacho et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

LAMA2-related myopathy: Frequency among congenital and limb-girdle muscular dystrophies

(2015) Nicoline Løkken et al.   MUSCLE & NERVE

The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

(2015) Sarah C. Petersen et al.   NEURON

Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

(2015) Hannah M. Stoveken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated Sequence Analysis Pipeline Provides One-Stop Solution for Identifying Disease-Causing Mutations

(2014) Hao Hu et al.   HUMAN MUTATION

Atypical phenotype in two patients with LAMA2 mutations

(2014) Joana Marques et al.   NEUROMUSCULAR DISORDERS

Changes in White Matter Integrity before Conversion from Mild Cognitive Impairment to Alzheimer’s Disease

(2014) Michaela Defrancesco et al.   PLoS One

Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126

(2014) K. J. Paavola et al.   Science Signaling

Gpr126 Functions in Schwann Cells to Control Differentiation and Myelination via G-Protein Activation

(2013) A. Mogha et al.   JOURNAL OF NEUROSCIENCE

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis

(2013) Shin H Kang et al.   NATURE NEUROSCIENCE

Alterations of mean diffusivity in brain white matter and deep gray matter in Parkinson's disease

(2013) Hengjun J. Kim et al.   NEUROSCIENCE LETTERS

Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent

(2013) C. Patra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sticky Signaling--Adhesion Class G Protein-Coupled Receptors Take the Stage

(2013) T. Langenhan et al.   Science Signaling

Abnormal white matter microstructure in children with sensory processing disorders

(2013) Julia P. Owen et al.   NeuroImage-Clinical

White matter tract integrity of frontostriatal circuit in attention deficit hyperactivity disorder: Association with attention performance and symptoms

(2012) Yi-Huan Wu et al.   HUMAN BRAIN MAPPING

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

(2011) Hossein Najmabadi et al.   NATURE

Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces

(2010) Hanka Venselaar et al.   BMC BIOINFORMATICS

Genotype–phenotype correlation in a large population of muscular dystrophy patients with LAMA2 mutations

(2010) Fatemeh Geranmayeh et al.   NEUROMUSCULAR DISORDERS

The Orphan Adhesion-GPCR GPR126 Is Required for Embryonic Development in the Mouse

(2010) Helen Waller-Evans et al.   PLoS One

White Matter Impairment in Rett Syndrome: Diffusion Tensor Imaging Study with Clinical Correlations

(2009) A. Mahmood et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

A G Protein-Coupled Receptor Is Essential for Schwann Cells to Initiate Myelination

(2009) K. R. Monk et al.   SCIENCE