Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice

Deletion of the Cathepsin B Gene Improves Memory Deficits in a Transgenic Alzheimer's Disease Mouse Model Expressing AβPP Containing the Wild-Type β-Secretase Site Sequence

(2018) Mark S. Kindy et al.   JOURNAL OF ALZHEIMERS DISEASE

Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging

(2017) Petra Füger et al.   NATURE NEUROSCIENCE

Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function

(2016) Hyo Youl Moon et al.   Cell Metabolism

Cathepsin B Improves ß-Amyloidosis and Learning and Memory in Models of Alzheimer’s Disease

(2016) Christine M Embury et al.   Journal of Neuroimmune Pharmacology

The Critical Role of Proteolytic Relay through Cathepsins B and E in the Phenotypic Change of Microglia/Macrophage

(2015) J. Ni et al.   JOURNAL OF NEUROSCIENCE

Rotenone impairs autophagic flux and lysosomal functions in Parkinson’s disease

(2015) F. Wu et al.   NEUROSCIENCE

Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia

(2013) Zhou Wu et al.   NEUROBIOLOGY OF AGING

Age-related decrease of the LAMP-2 gene expression in human leukocytes

(2012) Jian Huang et al.   CLINICAL BIOCHEMISTRY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM)

(2010) Y. Matsushima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia-aging: Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging

(2009) Hiroshi Nakanishi et al.   BEHAVIOURAL BRAIN RESEARCH

Genetic cathepsin B deficiency reduces β-amyloid in transgenic mice expressing human wild-type amyloid precursor protein

(2009) Vivian Y.H. Hook et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia

(2009) Kayo Terada et al.   GLIA

Reverse of Age-Dependent Memory Impairment and Mitochondrial DNA Damage in Microglia by an Overexpression of Human Mitochondrial Transcription Factor A in Mice

(2008) Y. Hayashi et al.   JOURNAL OF NEUROSCIENCE