4.8 Article

Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes

Journal

ADVANCED MATERIALS
Volume 30, Issue 51, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201803355

Keywords

artificial membranes; carbon nanotube porins; carbon nanotubes; fast transport; polymersomes

Funding

  1. Lawrence Graduate Scholar program at LLNL
  2. UC-Lab Fellowship
  3. Division of Materials Research of the National Science Foundation [1710211]
  4. U.S. Department of Energy, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering [SCW0972]
  5. U.S. Department of Energy [DE-AC52-07NA27344]
  6. Office of Science, Office of Basic Energy Sciences, U.S. Department of Energy [DE-AC02-05CH11231]
  7. U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences [DE-AC02-76SF00515]
  8. DOE Office of Biological and Environmental Research
  9. National Institutes of Health, National Institute of General Medical Sciences [P41GM103393]
  10. DOE [DE-AC05-76RL01830]
  11. Direct For Mathematical & Physical Scien [1710211] Funding Source: National Science Foundation
  12. Division Of Materials Research [1710211] Funding Source: National Science Foundation

Ask authors/readers for more resources

Biological membranes provide a fascinating example of a separation system that is multifunctional, tunable, precise, and efficient. Biomimetic membranes, which mimic the architecture of cellular membranes, have the potential to deliver significant improvements in specificity and permeability. Here, a fully synthetic biomimetic membrane is reported that incorporates ultra-efficient 1.5 nm diameter carbon nanotube porin (CNTPs) channels in a block-copolymer matrix. It is demonstrated that CNTPs maintain high proton and water permeability in these membranes. CNTPs can also mimic the behavior of biological gap junctions by forming bridges between vesicular compartments that allow transport of small molecules.

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