Comparative toxicity evaluation of targeted anticancer therapeutics in embryonic zebrafish and sea urchin models

Chemoresistance and chemosensitization in cholangiocarcinoma

(2018) Jose J.G. Marin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

K-Ras and its inhibitors towards personalized cancer treatment: Pharmacological and structural perspectives

(2017) Vivek Asati et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Targeting autophagy to modulate cell survival: a comparative analysis in cancer, normal and embryonic cells

(2017) Aleksandra Divac Rankov et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Triazole Fungicides Inhibit Zebrafish Hatching by Blocking the Secretory Function of Hatching Gland Cells

(2017) Javiera De la Paz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Strategies for monitoring and combating resistance to combination kinase inhibitors for cancer therapy

(2017) Leanne G. Ahronian et al.   Genome Medicine

Advancements in zebrafish applications for 21st century toxicology

(2016) Gloria R. Garcia et al.   PHARMACOLOGY & THERAPEUTICS

AZD2014 Radiosensitizes Oral Squamous Cell Carcinoma by Inhibiting AKT/mTOR Axis and Inducing G1/G2/M Cell Cycle Arrest

(2016) Chih-Chia Yu et al.   PLoS One

AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules

(2015) S. M. Guichard et al.   MOLECULAR CANCER THERAPEUTICS

Cell Proliferation Patterns in Early Zebrafish Development

(2014) Mario A. Mendieta-Serrano et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Targeting RAS–ERK signalling in cancer: promises and challenges

(2014) Ahmed A. Samatar et al.   NATURE REVIEWS DRUG DISCOVERY

Zebrafish models for assessing developmental and reproductive toxicity

(2014) Jian-Hui He et al.   NEUROTOXICOLOGY AND TERATOLOGY

Targeting RAS-MAPK-ERK and PI3K-AKT-mTOR signal transduction pathways to chemosensitize anaplastic thyroid carcinoma

(2014) Zorica Milosevic et al.   Translational Research

Dramatic suppression of colorectal cancer cell growth by the dual mTORC1 and mTORC2 inhibitor AZD-2014

(2013) Hai-zhong Huo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

The mTORC1/mTORC2 inhibitor AZD2014 enhances the radiosensitivity of glioblastoma stem-like cells

(2013) Jenna Kahn et al.   NEURO-ONCOLOGY

From Omics to Drug Metabolism and High Content Screen of Natural Product in Zebrafish: A New Model for Discovery of Neuroactive Compound

(2012) Ming Wai Hung et al.   Evidence-based Complementary and Alternative Medicine

Toxicity induced by emodin on zebrafish embryos

(2011) Qiuxia He et al.   DRUG AND CHEMICAL TOXICOLOGY

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

A review of personal care products in the aquatic environment: Environmental concentrations and toxicity

(2010) John M. Brausch et al.   CHEMOSPHERE

GSK690693 Delays Tumor Onset and Progression in Genetically Defined Mouse Models Expressing Activated Akt

(2010) D. A. Altomare et al.   CLINICAL CANCER RESEARCH

Initial testing (stage 1) of the Akt inhibitor GSK690693 by the pediatric preclinical testing program

(2010) Hernan Carol et al.   PEDIATRIC BLOOD & CANCER

The use ofin vivozebrafish assays in drug toxicity screening

(2009) Peter M Eimon et al.   Expert Opinion on Drug Metabolism & Toxicology

AKT inhibitor, GSK690693, induces growth inhibition and apoptosis in acute lymphoblastic leukemia cell lines

(2008) D. S. Levy et al.   BLOOD