PBPK Absorption Modeling of Food Effect and Bioequivalence in Fed State for Two Formulations with Crystalline and Amorphous Forms of BCS 2 Class Drug in Generic Drug Development

Title
PBPK Absorption Modeling of Food Effect and Bioequivalence in Fed State for Two Formulations with Crystalline and Amorphous Forms of BCS 2 Class Drug in Generic Drug Development
Authors
Keywords
physiologically based pharmacokinetic (PBPK) modeling, food effect, BCS, bioequivalence, amorphous formulation
Journal
AAPS PHARMSCITECH
Volume 20, Issue 2, Pages -
Publisher
Springer Nature
Online
2019-01-09
DOI
10.1208/s12249-018-1285-8

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