4.2 Article

Sphingomonas Paucimobilis Infections in Children: 24 Case Reports

Publisher

PAGEPRESS PUBL
DOI: 10.4084/MJHID.2013.040

Keywords

-

Ask authors/readers for more resources

Sphingomonas paucimobilis is a causative agent of infection in immunocompromised patients, and healthcare-associated infection. Although the infections associated with S. paucimobilis occurs rarely, it has been encountered with increasing frequency in clinical settings. In the current study we reported clinical features of the children with S. paucimobilis infection, and the antimicrobial susceptibilities of the isolated strains among the patients. This study was conducted in Dr. Behcet Uz Children's Hospital, Turkey, during the period of January 2005 and December 2012. The medical records of pediatric patients with positive cultures for S. paucimobilis were reviewed. Sphingomonas paucimobilis isolates were recovered from 24 pediatric patients. The median age was 4 years (ranging from 3 days infant to 15 years) and 58,3% were male. Eight (33,3%) of the patients were under 1 months of age. Among the patients; 13 (54,2%) infections were community related however 11(45.8%) infections were nosocomial infection. The median duration of hospital stay was 7 days (ranging from 4 to 22 days). The most effective antibiotics were fluoroquinolones, carbapenems, and trimethoprim/sulfamethoxazole. This is the first largest study in children to evaluate the clinical features of S. paucimobilis infections. Sphingomonas paucimobilis may cause infections in both previously healthy and immunocompromised children. Although variable antimicrobial regimens were achieved to the patients, there was no attributable fatality due to S. paucimobilis infections due to the low virulence of the bacteria.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Oncology

Evaluation for Metastatic Candida Focus and Mortality at Candida-associated Catheter-related Bloodstream Infections at the Pediatric Hematology-oncology Patients

Mine Duzgol, Elif Boncuoglu, Elif Kiymet, Aybuke Akaslan Kara, Melek Erdem, Isik Odaman Al, Bengu Demirag, Cuneyt Zihni, Tuba Hilkay Karapinar, Yesim Oymak, Timur Mese, Nuri Bayram, Ilker Devrim

Summary: This study focused on Candida-associated catheter-related bloodstream infections (CRBSIs) in pediatric hematologic/oncologic malignancies patients. The most common malignancies were acute lymphoblastic leukemia and acute myeloid leukemia. Candida parapsilosis was the most frequently isolated Candida species, while Candida tropicalis, C. parapsilosis, and C. lusitanae were the main species responsible for Candida-related deaths.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY (2022)

Article Virology

Comparison of the pediatric hospitalizations due to COVID-19 and H1N1pdm09 virus infections during the pandemic period

Ilker Devrim, Elif Boncuoglu, Elif Klymet, Sahika Sahinkaya, Miray Yilmaz Celebi, Ela Cem, Mine Duzgol, Kamile Otiken Arlkan, Aybuke Akaslan Kara, Fatma Devrim, Hasan Agin, Nuri Bayram

Summary: There are two major pandemics in the new millennium, including the pandemic of swine influenza and the COVID-19 pandemic. In this case-control study, children with COVID-19 infection were compared to those with H1N1pdm09 virus infection. The study found that older children were more likely to be hospitalized for COVID-19 infections compared to pandemic influenza. Additionally, underlying disease was a significant factor for pediatric intensive care unit admission, regardless of the type of pandemic infection.

JOURNAL OF MEDICAL VIROLOGY (2022)

Letter Immunology

A Diagnostic Challenge Is it Tuberculosis?

Elif Boncuoglu, Aybuke Akaslan Kara, Nuri Bayram, Ilker Devrim, Elif Kiymet, Ilknur Caglar, Bengu Demirag, Cenk Eraslan, Elif Bolat, Yesim Ertan, Serra Kamer, Aycan Unalp

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2022)

Letter Immunology

Do not Miss the Diagnosis of Bacterial Sepsis in Infants With COVID-19

Elif Boncuoglu, Elif Kiymet, Miray Yilmaz Celebi, Ela Cem, Mustafa Gulderen, Sahika Sahinkaya, Nuri Bayram, Ilker Devrim

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2022)

Article Mycology

Bloodstream infections due to Trichosporon species in paediatric patients: Results from the first national study from Turkey

Aybuke Akaslan Kara, Ummuhan Cay, Rumeysa Yalcinkaya, Emine Hafize Erdeniz, Tugce Tural Kara, Halil Ozdemir, Gizem Guner Ozenen, Meltem Polat, Zeynep Gokce Gayretli Aydin, Gulsum Alkan, Eda Kepenekli, Ozlem Ozgur Gundeslioglu, Elif Kiymet, Asuman Birinci, Filiz Kibar, Elif Boncuoglu, Zumrut Sahbudak Bal, Derya Alabaz, Ergin Ciftci, Gonul Tanir, Nuri Bayram, Ali Bulent Cengiz, Ilker Devrim

Summary: This study reviewed the characteristics, risk factors, treatment modalities, and outcomes of bloodstream infections caused by Trichosporon species in children in Turkey over the past ten years. The study found that invasive Trichosporon infections mainly affect immunocompromised patients with underlying diseases. Various antifungal treatment regimens were used, and voriconazole was associated with lower mortality rates.

JOURNAL DE MYCOLOGIE MEDICALE (2022)

Article Pediatrics

Evaluation of proximal tubule functions in children with COVID-19: a prospective analytical study

Fatma Devrim, Elif Boncuoglu, Elif Kiymet, Sahika Sahinkaya, Ela Cem, Mine Duzgol, Aybuke Akaslan Kara, Kamile Otiken Arikan, Asli Kantar, Ebru Yilmaz, Nida Dincel, Nuri Bayram, Ilker Devrim

Summary: This study found that approximately one in five children with acute COVID-19 infections had proximal tubular dysfunction. Although the rate was lower than in adults, it should still be noted and followed up on.

WORLD JOURNAL OF PEDIATRICS (2022)

Article Mycology

Changes in the incidence of Candida-related central line-associated bloodstream infections in pediatric intensive care unit: Could central line bundle have a role?

Lker Devrim, Sevgi Topal, Gokhan Ceylan, Yeliz Oruc, Gamze Gulfidan, Yuce Ayhan, Nuri Bayram, Hasan Agin

Summary: This study assessed the therapeutic benefit of a central line bundle in preventing Candida species-related bloodstream infections in pediatric intensive care units. The results showed that the central line bundle significantly reduced the incidence of central line-associated bloodstream infections caused by Candida species.

JOURNAL DE MYCOLOGIE MEDICALE (2022)

Article Cardiac & Cardiovascular Systems

Which Findings Make multisystem Inflammatory Syndrome in Children Different from the Pre-Pandemic Kawasaki Disease?

Ela Cem, Elif Boncuoglu, Elif Kiymet, Sahika Sahinkaya, Miray Yilmaz Celebi, Mustafa Gulderen, Pelin Kacar, Aybuke Akaslan Kara, Aysenur Aydin, Mehmet Murat, Murat Muhtar Yilmazer, Nuri Bayram, Ilker Devrim

Summary: Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 infection has similarities to Kawasaki disease but presents with different clinical and laboratory features. This study compared MIS-C patients with pre-pandemic Kawasaki disease patients and found that MIS-C patients were older and had more symptoms such as headaches, vomiting, and diarrhea. There were also differences in laboratory findings.

PEDIATRIC CARDIOLOGY (2023)

Letter Immunology

Did Hospitalization Age Decrease in Children in the Omicron (B.1.1.529) Era?

Elif Boncuoglu, Elif Kiymet, Sahika Sahinkaya, Ela Cem, Miray Yilmaz Celebi, Mustafa Gulderen, Pelin Kacar, Gizem Guner Ozenen, Aybuke Akaslan Kara, Nuri Bayram, Ilker Devrim

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2022)

Article Health Care Sciences & Services

Follow-Up of Cases with the Telemedicine Method During the COVID-19 Pandemic: An Alternative Strategy for Reduction of Hospital Workload and Hospital-Related Transmissions

Miray Yilmaz Celebi, Elif Kiymet, Elif Boncuoglu, Sahika Sahinkaya, Ela Cem, Mine Duzgol, Aybueke Akaslan Kara, Kamile Otiken Arikan, Dorukhan Besin, Suleyman Nuri Bayram, Ilker Devrim

Summary: This study evaluated the use of telemedicine in children with COVID-19, and found that interviews through telephone could help reduce patient burden and prevent contact with healthy individuals.

TELEMEDICINE AND E-HEALTH (2023)

Article Medicine, General & Internal

Evaluation of Changing Drug Preferences During the COVID-19 Pandemic in a Tertiary Childrens Hospital

Ela Cem, Elif Kiymet, Elif Boncuoglu, Sahika Sahinkaya, Miray Yilmaz Celebi, Mine Duzgol, Aybuke Akaslan Kara, Kamile Arikan, Nuri Bayram, Ilker Devrim

Summary: This study evaluated the treatment process of COVID-19 patients and found that supportive care is still the main therapeutic option. Oseltamivir treatment showed no efficacy, while the use of azithromycin and hydroxychloroquine decreased significantly. Favipiravir remains the first choice for drug treatment.

JOURNAL OF DR BEHCET UZ CHILDRENS HOSPITAL (2022)

Article Cardiac & Cardiovascular Systems

The Evaluation of Troponin I Levels and Myocarditis in Children with COVID-19: A Pediatric Single-Center Experience

Gizem Guner Ozenen, Aybuke Akaslan Kara, Elif Kiymet, Elif Boncuoglu, Sahika Sahinkaya, Ela Cem, Miray Yilmaz Celebi, Pelin Kacar, Mustafa Gulderen, Meltem Uras, Murat Muhtar Yilmazer, Mehmet Murat, Timur Mese, Hasan Agin, Nuri Bayram, Ilker Devrim

Summary: This study aimed to investigate the role of troponin I levels in predicting early cardiac involvement in children with COVID-19. The results showed that children with elevated troponin levels had longer hospital stays and were more likely to experience neutropenia, tachycardia, admission to the pediatric intensive care unit (PICU), oxygen support, and mechanical ventilation. Furthermore, most of the children with elevated troponin levels were diagnosed with myocarditis.

PEDIATRIC CARDIOLOGY (2023)

Article Pediatrics

Monitoring the Quality of Life in Dyspeptic Children with KINDL Scale

Ezgi Kiran Tasci, Ozlem Bekem Soylu, Onur Tasci, Ilker Gunay, Erhan Eser

Summary: The aim of this study was to evaluate the quality of life in patients with functional and organic dyspepsia and assess any changes during follow-up. It was found that both groups had affected quality of life and implementing recommendations and treatment improved the quality of life in both groups.

JOURNAL OF PEDIATRIC RESEARCH (2022)

Article Pediatrics

Rehospitalization indications of children hospitalized for COVID-19 infections after discharge: Should we suspect long COVID?

Ela Cem, Elif Kiymet, Elif Boncuoglu, Sahika Sahinkaya, Miray Yilmaz Celebi, Mustafa Gulderen, Gizem Guner Ozenen, Nuri Bayram, Ilker Devrim

Summary: This study discusses the conditions that may develop in children after COVID-19 infection and reviews the indications for rehospitalizations. The findings suggest that children without underlying diseases may experience complications from COVID-19 infection.

TURKISH JOURNAL OF PEDIATRICS (2023)

Letter Immunology

A Diagnostic Challenge Is it Tuberculosis?

Elif Boncuoglu, Aybuke Akaslan Kara, Nuri Bayram, Ilker Devrim, Elif Kiymet, Ilknur Caglar, Bengu Demirag, Cenk Eraslan, Elif Bolat, Yesim Ertan, Serra Kamer, Aycan Unalp

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2022)

No Data Available