Cardiovascular Risk Factors and Chronic Kidney Disease—FGF23: A Key Molecule in the Cardiovascular Disease

Effects of Dietary Phosphate Restriction and Phosphate Binders on FGF23 Levels in CKD

(2013) T. Isakova et al.   Clinical Journal of the American Society of Nephrology

The effect of phosphate binders, calcium and lanthanum carbonate on FGF23 levels in chronic kidney disease patients

(2013) Sagrario Soriano et al.   CLINICAL NEPHROLOGY

Cardiovascular Effects of Sevelamer in Stage 3 CKD

(2013) C. D. Chue et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Fibroblast growth factor 23 is not associated with and does not induce arterial calcification

(2013) Julia J. Scialla et al.   KIDNEY INTERNATIONAL

Fibroblast growth factor 23 accelerates phosphate-induced vascular calcification in the absence of Klotho deficiency

(2013) Rika Jimbo et al.   KIDNEY INTERNATIONAL

Early chronic kidney disease–mineral bone disorder stimulates vascular calcification

(2013) Yifu Fang et al.   KIDNEY INTERNATIONAL

Arterial Klotho Expression and FGF23 Effects on Vascular Calcification and Function

(2013) Karolina Lindberg et al.   PLoS One

Fibroblast growth factor 23 is associated with carotid artery calcification in chronic kidney disease patients not undergoing dialysis: a cross-sectional study

(2013) Masaru Nakayama et al.   BMC Nephrology

Cinacalcet lowering of serum fibroblast growth factor-23 concentration may be independent from serum Ca, P, PTH and dose of active vitamin D in peritoneal dialysis patients: a randomized controlled study

(2013) Hyo Jin Kim et al.   BMC Nephrology

Intact fibroblast growth factor 23 levels predict incident cardiovascular event before but not after the start of dialysis

(2012) Chikako Nakano et al.   BONE

Vascular Klotho Deficiency Potentiates the Development of Human Artery Calcification and Mediates Resistance to Fibroblast Growth Factor 23

(2012) Kenneth Lim et al.   CIRCULATION

(1-34) Parathyroid Hormone Infusion Acutely Lowers Fibroblast Growth Factor 23 Concentrations in Adult Volunteers

(2012) O. M. Gutierrez et al.   Clinical Journal of the American Society of Nephrology

Vitamin D Therapy and Cardiac Structure and Function in Patients With Chronic Kidney Disease

(2012) Ravi Thadhani et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

FGF23 neutralization improves chronic kidney disease–associated hyperparathyroidism yet increases mortality

(2012) Victoria Shalhoub et al.   JOURNAL OF CLINICAL INVESTIGATION

Vitamin D receptor activators inhibit vascular smooth muscle cell mineralization induced by phosphate and TNF- 

(2012) Y. Aoshima et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Role of vitamin D in vascular calcification: bad guy or good guy?

(2012) T. B. Drueke et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo

(2011) Yumie Rhee et al.   BONE

Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate

(2011) Catherine M. Shanahan et al.   CIRCULATION RESEARCH

Expression of FGF23/KLOTHO system in human vascular tissue

(2011) Javier Donate-Correa et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Fibroblast Growth Factor 23 and Risks of Mortality and End-Stage Renal Disease in Patients With Chronic Kidney Disease

(2011) Tamara Isakova   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

FGF23 induces left ventricular hypertrophy

(2011) Christian Faul et al.   JOURNAL OF CLINICAL INVESTIGATION

FGF-23 Associates with Death, Cardiovascular Events, and Initiation of Chronic Dialysis

(2011) J. Kendrick et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cardiovascular risk factors in chronic kidney disease: does phosphate qualify?

(2011) Keith Hruska et al.   KIDNEY INTERNATIONAL

Direct and indirect effects of parathyroid hormone on circulating levels of fibroblast growth factor 23 in vivo

(2011) Ignacio López et al.   KIDNEY INTERNATIONAL

Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease

(2011) Tamara Isakova et al.   KIDNEY INTERNATIONAL

Changes in fibroblast growth factor 23 during treatment of secondary hyperparathyroidism with alfacalcidol or paricalcitol

(2011) D. Hansen et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Lanthanum carbonate reduces FGF23 in chronic kidney disease Stage 3 patients

(2011) E. Gonzalez-Parra et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Cinacalcet treatment and serum FGF23 levels in haemodialysis patients with secondary hyperparathyroidism

(2011) M. Koizumi et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype

(2010) Hua Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fibroblast Growth Factor-23 in Early Chronic Kidney Disease: Additional Support in Favor of a Phosphate-Centric Paradigm for the Pathogenesis of Secondary Hyperparathyroidism

(2010) P. Evenepoel et al.   Clinical Journal of the American Society of Nephrology

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

(2010) Ming Chang Hu et al.   FASEB JOURNAL

Plasma fibroblast growth factor-23 levels are independently associated with carotid artery atherosclerosis in maintenance hemodialysis patients

(2010) Mustafa BALCI et al.   Hemodialysis International

Both FGF23 and extracellular phosphate activate Raf/MEK/ERK pathway via FGF receptors in HEK293 cells

(2010) Miwa Yamazaki et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Oxidized low-density lipoprotein promotes osteoblast differentiation in primary cultures of vascular smooth muscle cells by up-regulatingOsterixexpression in an Msx2-dependent manner

(2010) Jesse Taylor et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Calcemic Response to Continuous Parathyroid Hormone (PTH)(1-34) Infusion in End-Stage Kidney Disease Varies According to Bone Turnover: A Potential Role for PTH(7-84)

(2010) Katherine Wesseling-Perry et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

1,25-Dihydroxyvitamin D3-induced aortic calcifications in experimental uremia: up-regulation of osteoblast markers, calcium-transporting proteins and osterix

(2010) Hong Zebger-Gong et al.   JOURNAL OF HYPERTENSION

FGF23 Fails to Inhibit Uremic Parathyroid Glands

(2010) R. Canalejo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Increased parathyroid expression of klotho in uremic rats

(2010) Jacob Hofman-Bang et al.   KIDNEY INTERNATIONAL

Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease

(2010) Hisashi Hasegawa et al.   KIDNEY INTERNATIONAL

Calcitriol and doxercalciferol are equivalent in controlling bone turnover, suppressing parathyroid hormone, and increasing fibroblast growth factor-23 in secondary hyperparathyroidism

(2010) Katherine Wesseling-Perry et al.   KIDNEY INTERNATIONAL

Serum fibroblast growth factor-23 (FGF-23) levels are independently associated with left ventricular mass and myocardial performance index in maintenance haemodialysis patients

(2010) A. Kirkpantur et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Fibroblast growth factor-23 (FGF-23) is independently correlated to aortic calcification in haemodialysis patients

(2010) M. M. Nasrallah et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Pilot study of dietary phosphorus restriction and phosphorus binders to target fibroblast growth factor 23 in patients with chronic kidney disease

(2010) T. Isakova et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

FGF-23 and future cardiovascular events in patients with chronic kidney disease before initiation of dialysis treatment

(2010) S. Seiler et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Relation between serum fibroblast growth factor-23 level and mortality in incident dialysis patients: are gender and cardiovascular disease confounding the relationship?

(2010) H. Olauson et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Fibroblast Growth Factor 23 in Hemodialysis Patients: Effects of Phosphate Binder, Calcitriol and Calcium Concentration in the Dialysate

(2010) Ana L.E. Cancela et al.   NEPHRON CLINICAL PRACTICE

Plasma Parathyroid Hormone Level and Prevalent Cardiovascular Disease in CKD Stages 3 and 4: An Analysis From the Kidney Early Evaluation Program (KEEP)

(2009) Rohit Bhuriya et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition

(2009) Ritsuko Nakano-Kurimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Fibroblast Growth Factor 23: A Possible Cause of Left Ventricular Hypertrophy in Hemodialysis Patients

(2009) Heng Jung Hsu et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease

(2009) Orlando M. Gutiérrez et al.   CIRCULATION

Smooth Muscle Cells Give Rise to Osteochondrogenic Precursors and Chondrocytes in Calcifying Arteries

(2009) Mei Y. Speer et al.   CIRCULATION RESEARCH

Serum Phosphorus Concentrations and Arterial Stiffness among Individuals with Normal Kidney Function to Moderate Kidney Disease in MESA

(2009) J. H. Ix et al.   Clinical Journal of the American Society of Nephrology

Effects of Cinacalcet and Concurrent Low-Dose Vitamin D on FGF23 Levels in ESRD

(2009) J. B. Wetmore et al.   Clinical Journal of the American Society of Nephrology

Early Control of PTH and FGF23 in Normophosphatemic CKD Patients: A New Target in CKD-MBD Therapy?

(2009) R. B. Oliveira et al.   Clinical Journal of the American Society of Nephrology

Effects of hPTH(1-34) Infusion on Circulating Serum Phosphate, 1,25-Dihydroxyvitamin D, and FGF23 Levels in Healthy Men

(2009) Sherri-Ann M Burnett-Bowie et al.   JOURNAL OF BONE AND MINERAL RESEARCH

FGF23–parathyroid interaction: implications in chronic kidney disease

(2009) Hirotaka Komaba et al.   KIDNEY INTERNATIONAL

High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients

(2009) G. Jean et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Association of Serum Phosphate with Vascular and Valvular Calcification in Moderate CKD

(2008) K. L. Adeney et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Oral active vitamin D is associated with improved survival in hemodialysis patients

(2008) Manuel Naves-Díaz et al.   KIDNEY INTERNATIONAL

Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis

(2008) Orlando M. Gutiérrez et al.   NEW ENGLAND JOURNAL OF MEDICINE