Fatty Acid Metabolism in Pulmonary Arterial Hypertension: Role in Right Ventricular Dysfunction and Hypertrophy

Right ventricular reverse remodelling after balloon pulmonary angioplasty

(2014) S. Fukui et al.   EUROPEAN RESPIRATORY JOURNAL

Impact of Diabetes on Survival and Right Ventricular Compensation in Pulmonary Arterial Hypertension

(2014) Levi Benson et al.   Pulmonary Circulation

Evidence for Right Ventricular Lipotoxicity in Heritable Pulmonary Arterial Hypertension

(2013) Anna R. Hemnes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death

(2013) Valentina Parra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Geometry of the Randomized Evidence for Treatments of Pulmonary Hypertension

(2013) Adriano R. Tonelli et al.   Cardiovascular Therapeutics

Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension

(2013) Lin Piao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Heart energy metabolism impairment in Western-diet induced obese mice

(2013) Fabiana A. Neves et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Metabolic syndrome and left ventricular function: Is the number of criteria actually important?

(2013) Marijana Tadic et al.   MEDICAL SCIENCE MONITOR

Cardiac Magnetic Resonance Imaging: What Can It Add to Our Knowledge of the Right Ventricle in Pulmonary Arterial Hypertension?

(2012) Anton Vonk-Noordegraaf et al.   AMERICAN JOURNAL OF CARDIOLOGY

Lung18F-Fluorodeoxyglucose Positron Emission Tomography for Diagnosis and Monitoring of Pulmonary Arterial Hypertension

(2012) Glenn Marsboom et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dynamin-Related Protein 1–Mediated Mitochondrial Mitotic Fission Permits Hyperproliferation of Vascular Smooth Muscle Cells and Offers a Novel Therapeutic Target in Pulmonary Hypertension

(2012) Glenn Marsboom et al.   CIRCULATION RESEARCH

Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy Secondary to Pulmonary Arterial Hypertension

(2012) Jose Gomez-Arroyo et al.   Circulation-Heart Failure

Loss of ACE2 Exaggerates High-Calorie Diet–Induced Insulin Resistance by Reduction of GLUT4 in Mice

(2012) Masao Takeda et al.   DIABETES

Pathobiology of pulmonary arterial hypertension and right ventricular failure

(2012) Norbert F. Voelkel et al.   EUROPEAN RESPIRATORY JOURNAL

A potential role for insulin resistance in experimental pulmonary hypertension

(2012) James West et al.   EUROPEAN RESPIRATORY JOURNAL

HbA1c in pulmonary arterial hypertension: A marker of prognostic relevance?

(2012) Michael J. Belly et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate

(2012) Lin Piao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Increased Expression of Fatty-Acid and Calcium Metabolism Genes in Failing Human Heart

(2012) Vanessa García-Rúa et al.   PLoS One

CD36 as a target to prevent cardiac lipotoxicity and insulin resistance

(2012) Jan F.C. Glatz et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Metabolomic Analysis of Bone Morphogenetic Protein Receptor Type 2 Mutations in Human Pulmonary Endothelium Reveals Widespread Metabolic Reprogramming

(2012) Joshua P. Fessel et al.   Pulmonary Circulation

Caffeine-stimulated fatty acid oxidation is blunted in CD36 null mice

(2011) J. S. V. Lally et al.   Acta Physiologica

Absence of fatty acid transporter CD36 protects against Western-type diet-related cardiac dysfunction following pressure overload in mice

(2011) Laura K. M. Steinbusch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Molecular Signature of a Right Heart Failure Program in Chronic Severe Pulmonary Hypertension

(2011) Jennifer I. Drake et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

PET Imaging May Provide a Novel Biomarker and Understanding of Right Ventricular Dysfunction in Patients With Idiopathic Pulmonary Arterial Hypertension

(2011) Sabahat Bokhari et al.   Circulation-Cardiovascular Imaging

Metabolic Syndrome Impacts the Right Ventricle: True or False?

(2011) Marijana Tadic et al.   ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES

A Murine Model of Isolated Cardiac Steatosis Leads to Cardiomyopathy

(2011) Denis J. Glenn et al.   HYPERTENSION

Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle’s cycle

(2011) Yong-Hu Fang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Therapeutic targeting of cancer cell metabolism

(2011) Chi V. Dang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Increased CD36 expression in middle-aged mice contributes to obesity-related cardiac hypertrophy in the absence of cardiac dysfunction

(2011) Miranda M. Y. Sung et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Progressive Right Ventricular Dysfunction in Patients With Pulmonary Arterial Hypertension Responding to Therapy

(2011) Mariëlle C. van de Veerdonk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Intramyocardial triglyceride quantification by magnetic resonance spectroscopy: In vivo and ex vivo correlation in human subjects

(2011) Robert D. O'Connor et al.   MAGNETIC RESONANCE IN MEDICINE

Comparison of Body Habitus in Patients With Pulmonary Arterial Hypertension Enrolled in the Registry to Evaluate Early and Long-term PAH Disease Management With Normative Values From the National Health and Nutrition Examination Survey

(2011) Charles D. Burger et al.   MAYO CLINIC PROCEEDINGS

ACE2 Improves Right Ventricular Function in a Pressure Overload Model

(2011) Jennifer A. Johnson et al.   PLoS One

Plasma Levels of High-Density Lipoprotein Cholesterol and Outcomes in Pulmonary Arterial Hypertension

(2010) Gustavo A. Heresi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Diabetic cardiomyopathy in Zucker diabetic fatty rats: the forgotten right ventricle

(2010) Charissa E van den Brom et al.   Cardiovascular Diabetology

Rescue of Cardiomyopathy in Peroxisome Proliferator-Activated Receptor-α Transgenic Mice by Deletion of Lipoprotein Lipase Identifies Sources of Cardiac Lipids and Peroxisome Proliferator-Activated Receptor-α Activators

(2010) Jennifer G. Duncan et al.   CIRCULATION

Myocardial Steatosis and Biventricular Strain and Strain Rate Imaging in Patients With Type 2 Diabetes Mellitus

(2010) Arnold C.T. Ng et al.   CIRCULATION

Cardiovascular Parameters Correlated with Metabolic Syndrome in a Rural Community Cohort of Korea: The ARIRANG Study

(2010) Min-Soo Ahn et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

The PPARβ/δAgonist GW0742 Relaxes Pulmonary Vessels and Limits Right Heart Hypertrophy in Rats with Hypoxia-Induced Pulmonary Hypertension

(2010) Louise S. Harrington et al.   PLoS One

Influence of the Metabolic Syndrome Versus the Sum of Its Individual Components on Left Ventricular Geometry in Young Adults (from the Bogalusa Heart Study)

(2009) Dharmendrakumar A. Patel et al.   AMERICAN JOURNAL OF CARDIOLOGY

FAT/CD36-null mice reveal that mitochondrial FAT/CD36 is required to upregulate mitochondrial fatty acid oxidation in contracting muscle

(2009) Graham P. Holloway et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The Right Ventricle Under Pressure

(2009) Harm J. Bogaard et al.   CHEST

Harmonizing the Metabolic Syndrome

(2009) K.G.M.M. Alberti et al.   CIRCULATION

The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle

(2009) Lin Piao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Right but not left ventricular function recovers early after living-donor lobar lung transplantation in patients with pulmonary arterial hypertension

(2009) Shinichi Toyooka et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Abnormal Cardiac Structure and Function in the Metabolic Syndrome: A Population-Based Study

(2009) Bilal Aijaz et al.   MAYO CLINIC PROCEEDINGS

Insulin-induced translocation of CD36 to the plasma membrane is reversible and shows similarity to that of GLUT4

(2008) M VANOORT   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The malonyl CoA axis as a potential target for treating ischaemic heart disease

(2008) J. R. Ussher et al.   CARDIOVASCULAR RESEARCH

Insulin resistance in pulmonary arterial hypertension

(2008) R. T. Zamanian et al.   EUROPEAN RESPIRATORY JOURNAL

The impact of metabolic syndrome on left ventricular function: Evaluated by using the index of myocardial performance

(2008) Hasan Turhan et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Factor relationships of metabolic syndrome and echocardiographic phenotypes in the HyperGEN study

(2008) Pinchia Huang et al.   JOURNAL OF HYPERTENSION

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy

(2008) Tae-Sik Park et al.   JOURNAL OF LIPID RESEARCH

Modulation of total ceramide and constituent ceramide species in the acutely and chronically hypoxic mouse heart at different ages

(2008) Lama Noureddine et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS