New Insights into Control of Arbovirus Replication and Spread by Insect RNA Interference Pathways

Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus

(2012) Rebecca L Skalsky et al.   BMC GENOMICS

Sindbis virus induces the production of a novel class of endogenous siRNAs in Aedes aegypti mosquitoes

(2012) Z. N. Adelman et al.   INSECT MOLECULAR BIOLOGY

Targeting of Dicer-2 and RNA by a Viral RNA Silencing Suppressor in Drosophila Cells

(2012) N. Qi et al.   JOURNAL OF VIROLOGY

Arbovirus-Derived piRNAs Exhibit a Ping-Pong Signature in Mosquito Cells

(2012) Nicolas Vodovar et al.   PLoS One

Transmission dynamics of an insect-specific flavivirus in a naturally infected Culex pipiens laboratory colony and effects of co-infection on vector competence for West Nile virus

(2012) Bethany G. Bolling et al.   VIROLOGY

Production of Virus-Derived Ping-Pong-Dependent piRNA-like Small RNAs in the Mosquito Soma

(2012) Elaine M. Morazzani et al.   PLoS Pathogens

The mosquito Aedes aegypti has a large genome size and high transposable element load but contains a low proportion of transposon-specific piRNAs

(2011) Peter Arensburger et al.   BMC GENOMICS

Small RNA profiling of Dengue virus-mosquito interactions implicates the PIWI RNA pathway in anti-viral defense

(2011) Ann M Hess et al.   BMC MICROBIOLOGY

The endogenous siRNA pathway inDrosophilaimpacts stress resistance and lifespan by regulating metabolic homeostasis

(2011) Do-Hwan Lim et al.   FEBS LETTERS

Mosquito RNAi is the major innate immune pathway controlling arbovirus infection and transmission

(2011) Carol D Blair   Future Microbiology

Assembly of Alphavirus Replication Complexes from RNA and Protein Components in a Novel trans-Replication System in Mammalian Cells

(2011) P. Spuul et al.   JOURNAL OF VIROLOGY

Fossil Rhabdoviral Sequences Integrated into Arthropod Genomes: Ontogeny, Evolution, and Potential Functionality

(2011) P. Fort et al.   MOLECULAR BIOLOGY AND EVOLUTION

Alternative miRNA Biogenesis Pathways and the Interpretation of Core miRNA Pathway Mutants

(2011) Jr-Shiuan Yang et al.   MOLECULAR CELL

Evolution of microRNA diversity and regulation in animals

(2011) Eugene Berezikov   NATURE REVIEWS GENETICS

PIWI-interacting small RNAs: the vanguard of genome defence

(2011) Mikiko C. Siomi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Widespread expression of piRNA-like molecules in somatic tissues

(2011) Zheng Yan et al.   NUCLEIC ACIDS RESEARCH

Massive production of small RNAs from a non-coding region of Cauliflower mosaic virus in plant defense and viral counter-defense

(2011) Todd Blevins et al.   NUCLEIC ACIDS RESEARCH

Virus-encoded microRNAs

(2011) Adam Grundhoff et al.   VIROLOGY

Transcriptome Analysis of Aedes aegypti Transgenic Mosquitoes with Altered Immunity

(2011) Zhen Zou et al.   PLoS Pathogens

Engineered Anopheles Immunity to Plasmodium Infection

(2011) Yuemei Dong et al.   PLoS Pathogens

Combination of measures distinguishes pre-miRNAs from other stem-loops in the genome of the newly sequenced Anopheles darlingi

(2010) Nuno D Mendes et al.   BMC GENOMICS

The RNA interference pathway affects midgut infection- and escape barriers for Sindbis virus in Aedes aegypti

(2010) Cynthia CH Khoo et al.   BMC MICROBIOLOGY

First cases of autochthonous dengue fever and chikungunya fever in France: from bad dream to reality!

(2010) E.A. Gould et al.   CLINICAL MICROBIOLOGY AND INFECTION

Small RNA-Mediated Quiescence of Transposable Elements in Animals

(2010) Kuniaki Saito et al.   DEVELOPMENTAL CELL

Argonaute-mediated translational repression (and activation)

(2010) Shintaro Iwasaki et al.   FLY

Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila

(2010) A. D. Haase et al.   GENES & DEVELOPMENT

Argonaute proteins at a glance

(2010) C. Ender et al.   JOURNAL OF CELL SCIENCE

Antiviral RNA Interference Responses Induced by Semliki Forest Virus Infection of Mosquito Cells: Characterization, Origin, and Frequency-Dependent Functions of Virus-Derived Small Interfering RNAs

(2010) R. W. C. Siu et al.   JOURNAL OF VIROLOGY

Phosphatidylinositol 3-Kinase-, Actin-, and Microtubule-Dependent Transport of Semliki Forest Virus Replication Complexes from the Plasma Membrane to Modified Lysosomes

(2010) P. Spuul et al.   JOURNAL OF VIROLOGY

The arrival, establishment and spread of exotic diseases: patterns and predictions

(2010) Sarah E. Randolph et al.   NATURE REVIEWS MICROBIOLOGY

Functional microRNA generated from a cytoplasmic RNA virus

(2010) Harald Rouha et al.   NUCLEIC ACIDS RESEARCH

Toxoplasma gondii Infection Specifically Increases the Levels of Key Host MicroRNAs

(2010) Gusti M. Zeiner et al.   PLoS One

RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila

(2010) S. Mueller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs

(2010) Q. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Origins of alphavirus-derived small RNAs in mosquitoes

(2010) Kevin M. Myles et al.   RNA Biology

Noncanonical cytoplasmic processing of viral microRNAs

(2010) J. S. Shapiro et al.   RNA

Sequencing of Culex quinquefasciatus Establishes a Platform for Mosquito Comparative Genomics

(2010) P. Arensburger et al.   SCIENCE

piRNA-mediated silencing in Drosophila germlines

(2010) Mikiko C. Siomi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The piRNA pathway: a fly's perspective on the guardian of the genome

(2010) Kirsten-André Senti et al.   TRENDS IN GENETICS

Comparison of Dengue Virus Type 2-Specific Small RNAs from RNA Interference-Competent and –Incompetent Mosquito Cells

(2010) Jaclyn C. Scott et al.   PLoS Neglected Tropical Diseases

C6/36 Aedes albopictus Cells Have a Dysfunctional Antiviral RNA Interference Response

(2010) Doug E. Brackney et al.   PLoS Neglected Tropical Diseases

Present and future arboviral threats

(2009) Scott C. Weaver et al.   ANTIVIRAL RESEARCH

Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs

(2009) Song Li et al.   BMC GENOMICS

Suppression of RNA interference increases alphavirus replication and virus-associated mortality in Aedes aegypti mosquitoes

(2009) Chris M Cirimotich et al.   BMC MICROBIOLOGY

Evidence of a tick RNAi pathway by comparative genomics and reverse genetics screen of targets with known loss-of-function phenotypes in Drosophila

(2009) Sebastian Kurscheid et al.   BMC MOLECULAR BIOLOGY

Origin, Biogenesis, and Activity of Plant MicroRNAs

(2009) Olivier Voinnet   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Antiviral immunity in drosophila

(2009) Cordula Kemp et al.   CURRENT OPINION IN IMMUNOLOGY

Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences

(2009) Julia Verena Hartig et al.   EMBO JOURNAL

Stability and loss of a virus resistance phenotype over time in transgenic mosquitoes harbouring an antiviral effector gene

(2009) A. W. E. Franz et al.   INSECT MOLECULAR BIOLOGY

Advances in dissecting mosquito innate immune responses to arbovirus infection

(2009) R. Fragkoudis et al.   JOURNAL OF GENERAL VIROLOGY

Cell-to-Cell Spread of the RNA Interference Response Suppresses Semliki Forest Virus (SFV) Infection of Mosquito Cell Cultures and Cannot Be Antagonized by SFV

(2009) G. Attarzadeh-Yazdi et al.   JOURNAL OF VIROLOGY

Functional Analysis of a Cellular MicroRNA in Insect Host-Ascovirus Interaction

(2009) M. Hussain et al.   JOURNAL OF VIROLOGY

Aedes albopictus, an arbovirus vector: From the darkness to the light

(2009) C. Paupy et al.   MICROBES AND INFECTION

Drosophila Argonaute1 and Argonaute2 Employ Distinct Mechanisms for Translational Repression

(2009) Shintaro Iwasaki et al.   MOLECULAR CELL

Antiviral immunity in Drosophila requires systemic RNA interference spread

(2009) Maria-Carla Saleh et al.   NATURE

The microRNA bantam Functions in Epithelial Cells to Regulate Scaling Growth of Dendrite Arbors in Drosophila Sensory Neurons

(2009) Jay Z. Parrish et al.   NEURON

Bluetongue in Europe: past, present and future

(2009) A. J. Wilson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Viral Suppressors of RNA Silencing Hinder Exogenous and Endogenous Small RNA Pathways in Drosophila

(2009) Bassam Berry et al.   PLoS One

Chikungunya Virus and Aedes Mosquitoes: Saliva Is Infectious as soon as Two Days after Oral Infection

(2009) Mathieu Dubrulle et al.   PLoS One

The Endo-siRNA Pathway Is Essential for Robust Development of the Drosophila Embryo

(2009) Elena M. Lucchetta et al.   PLoS One

Dicing of viral replication intermediates during silencing of latent Drosophila viruses

(2009) A. Flynt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The endogenous siRNA pathway is involved in heterochromatin formation in Drosophila

(2009) Delphine Fagegaltier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C3PO, an Endoribonuclease That Promotes RNAi by Facilitating RISC Activation

(2009) Y. Liu et al.   SCIENCE

Small RNAs and the control of transposons and viruses in Drosophila

(2009) Ronald P. van Rij et al.   TRENDS IN MICROBIOLOGY

Dengue Virus Type 2 Infections of Aedes aegypti Are Modulated by the Mosquito's RNA Interference Pathway

(2009) Irma Sánchez-Vargas et al.   PLoS Pathogens

NF-kappaB p65-Dependent Transactivation of miRNA Genes following Cryptosporidium parvum Infection Stimulates Epithelial Cell Immune Responses

(2009) Rui Zhou et al.   PLoS Pathogens

RNAi Targeting of West Nile Virus in Mosquito Midguts Promotes Virus Diversification

(2009) Doug E. Brackney et al.   PLoS Pathogens

Comparative genomics of small RNA regulatory pathway components in vector mosquitoes

(2008) Corey L Campbell et al.   BMC GENOMICS

Aedes aegypti uses RNA interference in defense against Sindbis virus infection

(2008) Corey L Campbell et al.   BMC MICROBIOLOGY

Mechanism of Induction and Suppression of Antiviral Immunity Directed by Virus-Derived Small RNAs in Drosophila

(2008) Roghiyh Aliyari et al.   Cell Host & Microbe

Endogenous RNA Interference Provides a Somatic Defense against Drosophila Transposons

(2008) Wei-Jen Chung et al.   CURRENT BIOLOGY

microRNA-122 stimulates translation of hepatitis C virus RNA

(2008) Jura Inga Henke et al.   EMBO JOURNAL

RNA-based viral immunity initiated by the Dicer family of host immune receptors

(2008) Roghiyh Aliyari et al.   IMMUNOLOGICAL REVIEWS

An Insect Virus-Encoded MicroRNA Regulates Viral Replication

(2008) M. Hussain et al.   JOURNAL OF VIROLOGY

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

(2008) Yoshinori Kawamura et al.   NATURE

The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs

(2008) Katsutomo Okamura et al.   NATURE

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

(2008) Toshiaki Watanabe et al.   NATURE

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

(2008) Oliver H. Tam et al.   NATURE

An endogenous small interfering RNA pathway in Drosophila

(2008) Benjamin Czech et al.   NATURE

RIG-I-like antiviral protein in flies

(2008) Osamu Takeuchi et al.   NATURE IMMUNOLOGY

The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila

(2008) Safia Deddouche et al.   NATURE IMMUNOLOGY

Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster

(2008) Katsutomo Okamura et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alphavirus-derived small RNAs modulate pathogenesis in disease vector mosquitoes

(2008) K. M. Myles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells

(2008) M. Ghildiyal et al.   SCIENCE

Impact of climate change and other factors on emerging arbovirus diseases

(2008) E.A. Gould et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

West Nile virus infection of Drosophila melanogaster induces a protective RNAi response

(2008) Heather L. Chotkowski et al.   VIROLOGY