Role of MGMT as biomarker in colorectal cancer

Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation

(2013) F. Pietrantonio et al.   ANNALS OF ONCOLOGY

A phase I study of irinotecan in combination with metronomic temozolomide in patients with recurrent glioblastoma

(2013) Gaspar Reynés et al.   ANTI-CANCER DRUGS

Capecitabine and temozolomide (CAPTEM) for metastatic, well-differentiated neuroendocrine cancers: The Pancreas Center at Columbia University experience

(2013) Robert L. Fine et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Promoter CpG Island Hypermethylation of the DNA Repair Enzyme MGMT Predicts Clinical Response to Dacarbazine in a Phase II Study for Metastatic Colorectal Cancer

(2013) A. Amatu et al.   CLINICAL CANCER RESEARCH

A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the O6-Methylguanine-DNA Methyltransferase Promoter

(2013) D. Hochhauser et al.   MOLECULAR CANCER THERAPEUTICS

Predictive impact of MGMT promoter methylation in glioblastoma of the elderly

(2011) Guido Reifenberger et al.   INTERNATIONAL JOURNAL OF CANCER

Response to Temozolomide in Patients With Metastatic Colorectal Cancer With Loss of MGMT Expression: A New Approach in the Era of Personalized Medicine?

(2011) Einat Shacham-Shmueli et al.   JOURNAL OF CLINICAL ONCOLOGY

MEK-ERK Signaling Dictates DNA-Repair Gene MGMT Expression and Temozolomide Resistance of Stem-Like Glioblastoma Cells via the MDM2-p53 Axis

(2011) Atsushi Sato et al.   STEM CELLS

Promoter Methylation of Specific Genes is Associated with the Phenotype and Progression of Colorectal Adenocarcinomas

(2010) Jin C. Kim et al.   ANNALS OF SURGICAL ONCOLOGY

MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome

(2010) J C Hassel et al.   BRITISH JOURNAL OF CANCER

MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers

(2010) Kaori Shima et al.   CANCER CAUSES & CONTROL

Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers

(2010) M. Svrcek et al.   GUT

Pilot Study Using Molecular Profiling of Patients' Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers

(2010) Daniel D. Von Hoff et al.   JOURNAL OF CLINICAL ONCOLOGY

A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer

(2008) O A Khan et al.   BRITISH JOURNAL OF CANCER

Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas

(2008) Casilda Balmaceda et al.   CANCER