Binding of HIV-1 virions to α4β7 expressing cells and impact of antagonizing α4β7 on HIV-1 infection of primary CD4+ T cells

Envelope Glycoprotein Binding to the Integrin  4 7 Is Not a General Property of Most HIV-1 Strains

(2014) L. G. Perez et al.   JOURNAL OF VIROLOGY

The number and genetic relatedness of transmitted/founder virus impact clinical outcome in vaginal R5 SHIVSF162P3N infection

(2014) Lily Tsai et al.   Retrovirology

The two faces of vaccine-induced immune response: protection or increased risk of HIV infection?!

(2014) Vladimir Temchura et al.   VIROLOGICA SINICA

Blocking of integrins inhibits HIV-1 infection of human cervical mucosa immune cells with free and complement-opsonized virions

(2013) Veronica Tjomsland et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Frequency of α4β7high Memory CD4+ T Cells Correlates With Susceptibility to Rectal Simian Immunodeficiency Virus Infection

(2013) Elena Martinelli et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression

(2013) Katija Jelicic et al.   NATURE IMMUNOLOGY

Mechanisms of enhanced HIV spread through T-cell virological synapses

(2012) Benjamin M. Dale et al.   IMMUNOLOGICAL REVIEWS

Identification, Characterization, and Epitope Mapping of Human Monoclonal Antibody J19 That Specifically Recognizes Activated Integrin α4β7

(2012) JunPeng Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural specializations of α4β7, an integrin that mediates rolling adhesion

(2012) Yamei Yu et al.   JOURNAL OF CELL BIOLOGY

Envelopes found early after acquisition compared to those in the chronically infected partner do not have enhanced alpha4 beta7 binding or utilization

(2012) B Etemad et al.   Retrovirology

Transmitted/Founder and Chronic Subtype C HIV-1 Use CD4 and CCR5 Receptors with Equal Efficiency and Are Not Inhibited by Blocking the Integrin α4β7

(2012) Nicholas F. Parrish et al.   PLoS Pathogens

HIV envelope-mediated, CCR5/ 4 7-dependent killing of CD4-negative    T cells which are lost during progression to AIDS

(2011) H. Li et al.   BLOOD

Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

(2011) Maud Mavigner et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of a Human Cervical CD4+ T Cell Subset Coexpressing Multiple Markers of HIV Susceptibility

(2011) L. R. McKinnon et al.   JOURNAL OF IMMUNOLOGY

HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV

(2011) Claudia Cicala et al.   Journal of Translational Medicine

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

(2011) Jason S. McLellan et al.   NATURE

Polymorphisms in the α4 Integrin of Neotropical Primates: Insights for Binding of Natural Ligands and HIV-1 gp120 to the Human α4β7

(2011) Mirela Darc et al.   PLoS One

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

(2011) A. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WFDC1 expression identifies memory CD4 T- lymphocytes rendered vulnerable to cell-cell HIV-1 transfer by promoting intercellular adhesive junctions

(2011) Raymond A Alvarez et al.   Retrovirology

Genotypic and functional properties of early infant HIV-1 envelopes

(2011) Michael Kishko et al.   Retrovirology

The Genotype of Early-Transmitting HIV gp120s Promotes α4β7 –Reactivity, Revealing α4β7+/CD4+ T cells As Key Targets in Mucosal Transmission

(2011) Fatima Nawaz et al.   PLoS Pathogens

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

Innate immunity against HIV: a priority target for HIV prevention research

(2010) Persephone Borrow et al.   Retrovirology

The Ins and Outs of Leukocyte Integrin Signaling

(2009) Clare L. Abram et al.   Annual Review of Immunology

Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies

(2009) Marie-Claude Boily et al.   LANCET INFECTIOUS DISEASES

Monitoring α4β7 integrin expression on circulating CD4+ T cells as a surrogate marker for tracking intestinal CD4+ T-cell loss in SIV infection

(2009) X Wang et al.   Mucosal Immunology

The integrin  4 7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

(2009) C. Cicala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular architecture of native HIV-1 gp120 trimers

(2008) Jun Liu et al.   NATURE

HIV's gut feeling

(2008) Quentin Sattentau   NATURE IMMUNOLOGY

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

(2008) James Arthos et al.   NATURE IMMUNOLOGY

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA