Trametinib, a novel MEK kinase inhibitor, suppresses lipopolysaccharide-induced tumor necrosis factor (TNF)-α production and endotoxin shock

Published 2015 View Full Article

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Title
Trametinib, a novel MEK kinase inhibitor, suppresses lipopolysaccharide-induced tumor necrosis factor (TNF)-α production and endotoxin shock
Authors
Keywords
Lipopolysaccharide (LPS), Trametinib, Tumor necrosis factor (TNF)-α, MEK-ERK signaling and endotoxin shock
Journal
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Volume 458, Issue 3, Pages 667-673
Publisher
Elsevier BV
Online
2015-02-14
DOI
10.1016/j.bbrc.2015.01.160

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