Article
Medicine, General & Internal
Gerardo Garcia-Aguirre, Andree Henaine-Berra, Guillermo Salcedo-Villanueva
Summary: This study used dynamic ultra-widefield infrared confocal scanning laser ophthalmoscopy to analyze the appearance of vitreous opacities. The most common cause of vitreous floaters was posterior vitreous detachment, and the severity of opacities was correlated with age.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Ophthalmology
Elise Bakker, Felix Anne Dikland, Roan van Bakel, Danilo Andrade De Jesus, Luisa Sanchez Brea, Stefan Klein, Theo van Walsum, Florence Rossant, Daniela Castro Farias, Kate Grieve, Michel Paques
Summary: This article provides a systematic review of retinal vascular biomarkers imaged by adaptive optics. It highlights the frequently studied biomarkers and calls for further clinical research and standardization to validate their application.
SURVEY OF OPHTHALMOLOGY
(2022)
Review
Optics
Lixin Liu, Zhaoqing Wu, Meijie Qi, Yanru Li, Meiling Zhang, Dingying Liao, Peng Gao
Summary: The eye is crucial for humans to perceive the external environment. Ocular aberrations limit the observation of eye structures and the exploration of eye disease mechanisms. Adaptive optics technology corrects these aberrations, enabling cellular-level retinal imaging.
Article
Computer Science, Information Systems
Salma M. Boubakar Khalifa Albargathe, Ersin Kamberli, Fatma Kandemirli, Javad Rahebi
Summary: This study utilized the H-minima transform for blood vessel segmentation in retinal images, achieving good results and performance. The method showed remarkable performance on pathological retinal images, with an average accuracy of 0.9591 and 0.9672 for STARE dataset and DRIVE dataset respectively. The running time of the method was 1 second per image.
MULTIMEDIA TOOLS AND APPLICATIONS
(2021)
Review
Oncology
Almut Bindewald-Wittich, Frank G. Holz, Thomas Ach, Miltiadis Fiorentzis, Nikolaos E. Bechrakis, Gregor D. Willerding
Summary: Fundus autofluorescence imaging is a non-invasive technique that allows for in vivo detection of intrinsic fluorescence in the ocular fundus. It can provide topographic autofluorescence mapping and is helpful for differential diagnosis and monitoring of choroidal melanoma before and after treatment.
Review
Medicine, Research & Experimental
Xincheng Yao, Taeyoon Son, Jiechao Ma
Summary: This article reviews recent developments in alternative illumination approaches for widefield fundus photography, including miniaturized indirect illumination, contact mode trans-pars-planar illumination, and contact-free trans-pars-planar illumination. These methods enable the development of low-cost, portable, widefield fundus cameras, facilitating the popularization of teleophthalmology.
EXPERIMENTAL BIOLOGY AND MEDICINE
(2022)
Article
Medicine, General & Internal
Mircea Mujat, James D. Akula, Anne B. Fulton, R. Daniel Ferguson, Nicusor Iftimia
Summary: Adaptive optics improves resolution in ophthalmic imaging for identifying, counting, and mapping retinal microstructures. Small patches can be registered using cross-correlation, but larger images require more sophisticated techniques. We have applied a non-rigid registration technique to compensate for local image deformations, resulting in improved definition of retinal microstructures. Evaluation of derived metrics can facilitate early diagnostics of retinal diseases.
Article
Biochemistry & Molecular Biology
Jasdeep S. Gill, Vasileios Theofylaktopoulos, Andreas Mitsios, Sarah Houston, Ahmed M. Hagag, Adam M. Dubis, Mariya Moosajee
Summary: This study evaluated retinal imaging in USH2A retinopathy patients and found that EZ width is the most sensitive biomarker of structural and functional decline, making it a promising trial endpoint.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Ophthalmology
Qian Zhang, Konstantina Sampani, Mengjia Xu, Shengze Cai, Yixiang Deng, He Li, Jennifer K. Sun, George Em Karniadakis
Summary: This study introduces AOSLO-net, an automatic segmentation method for microaneurysms (MAs) in diabetic retinas from AOSLO images. AOSLO-net achieves high-quality MA segmentation through customized preprocessing and postprocessing strategies, and outperforms the state-of-the-art segmentation model.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2022)
Article
Ophthalmology
Aubrey Hargrave, Nripun Sredar, Fareshta Khushzad, Jennifer Yarp, Anna Tomczak, May Han, Lucas Kipp, Alfredo Dubra, Heather E. Moss
Summary: AOSLO imaging of the foveal avascular zone in MS patients revealed two distinct structures, with hyperreflective puncta associated with ocular perfusion and scattering features linked to advanced MS progression. Both features may impact visual function in MS patients independently of retinal ganglion cell injury.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Medicine, General & Internal
Fabrizio Giansanti, Stefano Mercuri, Federica Serino, Tomaso Caporossi, Alfonso Savastano, Clara Rizzo, Francesco Faraldi, Stanislao Rizzo, Daniela Bacherini
Summary: This study aimed to evaluate the ability of SLO retromode imaging compared to FAF in identifying outer retinal features in CSCR patients. The results showed that SLO retromode imaging had higher sensitivity than FAF in detecting SRF and RPE dystrophy, but it couldn't provide qualitative information about lesion depth and RPE cell health status.
Article
Biochemical Research Methods
Ehsan Golkar, Hossein Rabbani, Alireza Dehghani
Summary: This paper presents a hybrid registration framework based on the extraction of blood vessels in retinal images, which significantly improves the success rate of global registration in complex retinal images, providing promising results for the diagnosis of DR.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Ophthalmology
NikhilS Choudhari, Sanjay Kumar, Ashutosh Richhariya, Rashmi Krishnamurthy, Ruchi Priya, ChandraSekhar Garudadri
Summary: This study compared the image characteristics of RNFL between glaucoma patients and healthy controls using AOSLO, revealing differences between early glaucoma and controls. However, imaging success rate was lower in moderate and severe glaucoma groups, with indiscernible RNFL bundles and similar reflectivity compared to the early glaucoma group.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Rait Parmann, Stephen H. Tsang, Jana Zernant, Rando Allikmets, Vivienne C. Greenstein, Janet R. Sparrow
Summary: The commonly used autofluorescence detection methods may underestimate the size of ABCA4-associated retinopathy lesions.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2022)
Article
Ophthalmology
Hirofumi Morita, Itsuka Matsushita, Yoshihisa Fujino, Akira Obana, Hiroyuki Kondo
Summary: The purpose of this study was to develop a method to measure macular pigment optical density (MPOD) using scanning laser ophthalmoscopic images in young adults and children. The method involved generating a profile of linear reflectance changes across the center of the fovea on grayscale fundus images. The results showed that this simplified method provided accurate and reliable values of MPOD, comparable to heterochromatic flicker photometry. The method is fast and easy, making it suitable for use with children.
JAPANESE JOURNAL OF OPHTHALMOLOGY
(2023)
