Modeling of Particulate Processes for the Continuous Manufacture of Solid-Based Pharmaceutical Dosage Forms
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Modeling of Particulate Processes for the Continuous Manufacture of Solid-Based Pharmaceutical Dosage Forms
Authors
Keywords
-
Journal
Processes
Volume 1, Issue 2, Pages 67-127
Publisher
MDPI AG
Online
2013-08-20
DOI
10.3390/pr1020067
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Use of the bootstrap and permutation methods for a more robust variable importance in the projection metric for partial least squares regression
- (2013) N.L. Afanador et al. ANALYTICA CHIMICA ACTA
- Reduced-order discrete element method modeling
- (2013) Fani Boukouvala et al. CHEMICAL ENGINEERING SCIENCE
- In-line monitoring of the drug content of powder mixtures and tablets by near-infrared spectroscopy during the continuous direct compression tableting process
- (2013) Kristiina Järvinen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- System-wide hybrid MPC–PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction
- (2013) Ravendra Singh et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Use of near-infrared spectroscopy to quantify drug content on a continuous blending process: Influence of mass flow and rotation speed variations
- (2013) Lizbeth Martínez et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Multi-scale flowsheet simulation of an integrated continuous purification–downstream pharmaceutical manufacturing process
- (2013) Maitraye Sen et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- General procedure to aid the development of continuous pharmaceutical processes using multivariate statistical modeling – An industrial case study
- (2013) Emanuele Tomba et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Radial hopper flow prediction using a constitutive model with microstructure evolution
- (2013) Jin Sun et al. POWDER TECHNOLOGY
- Evaluation of the effects of process parameters on granule mean size in a conical high shear granulator using response surface methodology
- (2013) S. Ranjbarian et al. POWDER TECHNOLOGY
- Development of a methodology to estimate error in the on-line measurements of blend uniformity in a continuous powder mixing process
- (2013) Aditya U. Vanarase et al. POWDER TECHNOLOGY
- Computer-Aided Flowsheet Simulation of a Pharmaceutical Tablet Manufacturing Process Incorporating Wet Granulation
- (2013) Fani Boukouvala et al. Journal of Pharmaceutical Innovation
- A multi-dimensional population balance model approach to continuous powder mixing processes
- (2012) Maitraye Sen et al. ADVANCED POWDER TECHNOLOGY
- Reduction of a single granule drying model: An essential step in preparation of a population balance model with a continuous growth term
- (2012) Séverine Thérèse F.C. Mortier et al. AICHE JOURNAL
- A modelling approach for derivation of the breakage functions
- (2012) Eduard N. Tsoy CHEMICAL ENGINEERING SCIENCE
- Numerical modelling of suction filling using DEM/CFD
- (2012) Chuan-Yu Wu et al. CHEMICAL ENGINEERING SCIENCE
- Multi-dimensional population balance modeling and experimental validation of continuous powder mixing processes
- (2012) Maitraye Sen et al. CHEMICAL ENGINEERING SCIENCE
- Optimizing continuous powder mixing processes using periodic section modeling
- (2012) Yijie Gao et al. CHEMICAL ENGINEERING SCIENCE
- A multiscale model for the simulation of granulation in rotor-based equipment
- (2012) J. Bouffard et al. CHEMICAL ENGINEERING SCIENCE
- A comparison of model order reduction techniques for a four-dimensional population balance model describing multi-component wet granulation processes
- (2012) Dana Barrasso et al. CHEMICAL ENGINEERING SCIENCE
- Regime map development for continuous twin screw granulation
- (2012) Wei-Da Tu et al. CHEMICAL ENGINEERING SCIENCE
- Bootstrap based confidence limits in principal component analysis — A case study
- (2012) Hamid Babamoradi et al. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
- A reduced-order model for heat transfer in multiphase flow and practical aspects of the proper orthogonal decomposition
- (2012) Thomas A. Brenner et al. COMPUTERS & CHEMICAL ENGINEERING
- A perspective on PSE in pharmaceutical process development and innovation
- (2012) Krist V. Gernaey et al. COMPUTERS & CHEMICAL ENGINEERING
- An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process
- (2012) Fani Boukouvala et al. COMPUTERS & CHEMICAL ENGINEERING
- Development of a Population Balance Model of a pharmaceutical drying process and testing of solution methods
- (2012) Séverine Thérèse F.C. Mortier et al. COMPUTERS & CHEMICAL ENGINEERING
- Process systems engineering tools in the pharmaceutical industry
- (2012) Gregory M. Troup et al. COMPUTERS & CHEMICAL ENGINEERING
- Toward a low cost and high performance MPC: The role of system identification
- (2012) Yucai Zhu et al. COMPUTERS & CHEMICAL ENGINEERING
- Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release
- (2012) Maiju A. Järvinen et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT)
- (2012) Buket Aksu et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Continuous twin screw granulation: Influence of process variables on granule and tablet quality
- (2012) J. Vercruysse et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- A comparative study of roll compaction of free-flowing and cohesive pharmaceutical powders
- (2012) Shen Yu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Methods for the practical determination of the mechanical strength of tablets—From empiricism to science
- (2012) Fridrun Podczeck INTERNATIONAL JOURNAL OF PHARMACEUTICS
- An engineering study on the enhanced control and operation of continuous manufacturing of pharmaceutical tablets via roller compaction
- (2012) Ravendra Singh et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Contact drying: A review of experimental and mechanistic modeling approaches
- (2012) Ekneet Kaur Sahni et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Contribution of the Physicochemical Properties of Active Pharmaceutical Ingredients to Tablet Properties Identified by Ensemble Artificial Neural Networks and Kohonen's Self-Organizing Maps
- (2012) Yoshinori Onuki et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Mechanistic Insights into the Dissolution of Spray-Dried Amorphous Solid Dispersions
- (2012) Zoe A. Langham et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A method of MPC model error detection
- (2012) Guoli Ji et al. JOURNAL OF PROCESS CONTROL
- Modelling die filling with charged particles using DEM/CFD
- (2012) Emmanuel Nkem Nwose et al. Particuology
- Comparison of flow microdynamics for a continuous granular mixer with predictions from periodic slice DEM simulations
- (2012) Avik Sarkar et al. POWDER TECHNOLOGY
- A review of the Residence Time Distribution (RTD) applications in solid unit operations
- (2012) Yijie Gao et al. POWDER TECHNOLOGY
- Method for characterization of loss-in-weight feeder equipment
- (2012) William E. Engisch et al. POWDER TECHNOLOGY
- The use of single particle mechanical properties for predicting the compressibility of pharmaceutical materials
- (2012) Biljana Govedarica et al. POWDER TECHNOLOGY
- Twin screw wet granulation: Effects of properties of granulation liquid
- (2012) Ranjit M. Dhenge et al. POWDER TECHNOLOGY
- Multi-component population balance modeling of granulation with continuous addition of binder
- (2012) Carl L. Marshall et al. POWDER TECHNOLOGY
- Comparison of granule properties produced using Twin Screw Extruder and High Shear Mixer: A step towards understanding the mechanism of twin screw wet granulation
- (2012) Kai T. Lee et al. POWDER TECHNOLOGY
- Twin screw wet granulation: Loss in weight feeding of a poorly flowing active pharmaceutical ingredient
- (2012) James J. Cartwright et al. POWDER TECHNOLOGY
- Quantitative model validation techniques: New insights
- (2012) You Ling et al. RELIABILITY ENGINEERING & SYSTEM SAFETY
- 3D Simulation of Internal Tablet Strength During Tableting
- (2011) Simo Matti Siiriä et al. AAPS PHARMSCITECH
- Periodic section modeling of convective continuous powder mixing processes
- (2011) Yijie Gao et al. AICHE JOURNAL
- Comparison of near infrared and microwave resonance sensors for at-line moisture determination in powders and tablets
- (2011) Claudia C. Corredor et al. ANALYTICA CHIMICA ACTA
- Model validation and error estimation in multi-block partial least squares regression
- (2011) Sahar Hassani et al. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
- Optimization of IGCC processes with reduced order CFD models
- (2011) Yidong Lang et al. COMPUTERS & CHEMICAL ENGINEERING
- Feasibility analysis of black-box processes using an adaptive sampling Kriging-based method
- (2011) Fani Boukouvala et al. COMPUTERS & CHEMICAL ENGINEERING
- Mechanistic modelling of fluidized bed drying processes of wet porous granules: A review
- (2011) Séverine Thérèse F.C. Mortier et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Dynamic Data-Driven Modeling of Pharmaceutical Processes
- (2011) F. Boukouvala et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study
- (2011) Spencer D. Schaber et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- Coordination Number of the Packing of Ternary Mixtures of Spheres: DEM Simulations versus Measurements
- (2011) L. Y. Yi et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- Original predictive approach to the compressibility of pharmaceutical powder mixtures based on the Kawakita equation
- (2011) Vincent Mazel et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Discrete element method (DEM) simulations of stratified sampling during solid dosage form manufacturing
- (2011) Bruno C. Hancock et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Cone milling of compacted flakes: Process parameter selection by adopting the minimal fines approach
- (2011) A.K. Samanta et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A constitutive model with microstructure evolution for flow of rate-independent granular materials
- (2011) JIN SUN et al. JOURNAL OF FLUID MECHANICS
- Compressibility of Binary Powder Formulations: Investigation and Evaluation with Compaction Equations
- (2011) Nicolaos D. Gentis et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Computational Approaches for Studying the Granular Dynamics of Continuous Blending Processes, 2 - Population Balance and Data-Based Methods
- (2011) Fani Boukouvala et al. MACROMOLECULAR MATERIALS AND ENGINEERING
- Quantitative analysis of multi-particle interactions during particle breakage: A discrete non-linear population balance framework
- (2011) Ecevit Bilgili et al. POWDER TECHNOLOGY
- An experimental evaluation of the accuracy to simulate granule bed compression using the discrete element method
- (2011) Ann-Sofie Persson et al. POWDER TECHNOLOGY
- Modeling the powder roll compaction process: Comparison of 2-D finite element method and the rolling theory for granular solids (Johanson's model)
- (2011) Ariel R. Muliadi et al. POWDER TECHNOLOGY
- Model-Based Control-Loop Performance of a Continuous Direct Compaction Process
- (2011) Rohit Ramachandran et al. Journal of Pharmaceutical Innovation
- Characterization of feeder effects on continuous solid mixing using fourier series analysis
- (2010) Yijie Gao et al. AICHE JOURNAL
- Predictive modeling of pharmaceutical processes with missing and noisy data
- (2010) Fani Boukouvala et al. AICHE JOURNAL
- Future manufacturing approaches in the chemical and pharmaceutical industry
- (2010) Sigurd Buchholz CHEMICAL ENGINEERING AND PROCESSING
- Modelling of pharmaceutical granule size reduction in a conical screen mill
- (2010) Gavin K. Reynolds CHEMICAL ENGINEERING JOURNAL
- Conceptual design and simulation of a plant for the production of high purity (S)-ibuprofen acid using innovative enzymatic membrane technology
- (2010) Sie Yon Lau et al. CHEMICAL ENGINEERING JOURNAL
- Reducing the mean size of API crystals by continuous manufacturing with product classification and recycle
- (2010) Derek W. Griffin et al. CHEMICAL ENGINEERING SCIENCE
- Experiments and simulations of cohesionless particles with varying roughness in a bladed mixer
- (2010) Brenda Remy et al. CHEMICAL ENGINEERING SCIENCE
- Investigation of the effect of impeller rotation rate, powder flow rate, and cohesion on powder flow behavior in a continuous blender using PEPT
- (2010) Patricia M. Portillo et al. CHEMICAL ENGINEERING SCIENCE
- Real-time monitoring of drug concentration in a continuous powder mixing process using NIR spectroscopy
- (2010) Aditya U. Vanarase et al. CHEMICAL ENGINEERING SCIENCE
- A model-based systems approach to pharmaceutical product-process design and analysis
- (2010) Krist V. Gernaey et al. CHEMICAL ENGINEERING SCIENCE
- Effective parameter estimation within a multi-dimensional population balance model framework
- (2010) Rohit Ramachandran et al. CHEMICAL ENGINEERING SCIENCE
- Compression mechanics of granule beds: A combined finite/discrete element study
- (2010) Göran Frenning CHEMICAL ENGINEERING SCIENCE
- Polydisperse granular flows in a bladed mixer: Experiments and simulations of cohesionless spheres
- (2010) Brenda Remy et al. CHEMICAL ENGINEERING SCIENCE
- Characterizing continuous powder mixing using residence time distribution
- (2010) Yijie Gao et al. CHEMICAL ENGINEERING SCIENCE
- Optimizing the design of eccentric feed hoppers for tablet presses using DEM
- (2010) William R. Ketterhagen et al. COMPUTERS & CHEMICAL ENGINEERING
- Process/equipment co-simulation for design and analysis of advanced energy systems
- (2010) Stephen E. Zitney COMPUTERS & CHEMICAL ENGINEERING
- Computationally efficient black-box modeling for feasibility analysis
- (2010) Ipsita Banerjee et al. COMPUTERS & CHEMICAL ENGINEERING
- Practical application of roller compaction process modeling
- (2010) Gavin Reynolds et al. COMPUTERS & CHEMICAL ENGINEERING
- Microstructure-based mathematical modelling and spectroscopic imaging of tablet dissolution
- (2010) James A. Kimber et al. COMPUTERS & CHEMICAL ENGINEERING
- Lubrication in tablet formulations
- (2010) Jennifer Wang et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Reduced order modelling method via proper orthogonal decomposition (POD) for flow around an oscillating cylinder
- (2010) E. Liberge et al. JOURNAL OF FLUIDS AND STRUCTURES
- Quantitative validation of the discrete element method using an annular shear cell
- (2010) J.J. McCarthy et al. POWDER TECHNOLOGY
- 3D DEM/CFD analysis of size-induced segregation during die filling
- (2010) Y. Guo et al. POWDER TECHNOLOGY
- Identification of the breakage rate and distribution parameters in a non-linear population balance model for batch milling
- (2010) Maxx Capece et al. POWDER TECHNOLOGY
- Study of cold powder compaction by using the discrete element method
- (2010) J.-F. Jerier et al. POWDER TECHNOLOGY
- Effect of operating conditions and design parameters in a continuous powder mixer
- (2010) Aditya U. Vanarase et al. POWDER TECHNOLOGY
- Continuous quantitative monitoring of powder mixing dynamics by near-infrared spectroscopy
- (2010) D.M. Koller et al. POWDER TECHNOLOGY
- Population Balance Model-Based Hybrid Neural Network for a Pharmaceutical Milling Process
- (2010) Pavan Kumar Akkisetty et al. Journal of Pharmaceutical Innovation
- Design Space of Pharmaceutical Processes Using Data-Driven-Based Methods
- (2010) Fani Boukouvala et al. Journal of Pharmaceutical Innovation
- Modeling and Control of Roller Compaction for Pharmaceutical Manufacturing. Part I: Process Dynamics and Control Framework
- (2010) Shuo-Huan Hsu et al. Journal of Pharmaceutical Innovation
- Good modeling practice for PAT applications: Propagation of input uncertainty and sensitivity analysis
- (2009) Gürkan Sin et al. BIOTECHNOLOGY PROGRESS
- A mechanistic model for breakage in population balances of granulation: Theoretical kernel development and experimental validation
- (2009) Rohit Ramachandran et al. CHEMICAL ENGINEERING RESEARCH & DESIGN
- Computer-aided design and scale-up of crystallization processes: Integrating approaches and case studies
- (2009) Hong-yuan Wei CHEMICAL ENGINEERING RESEARCH & DESIGN
- ICAS-PAT: A software for design, analysis and validation of PAT systems
- (2009) Ravendra Singh et al. COMPUTERS & CHEMICAL ENGINEERING
- Reduced Order Model Based on Principal Component Analysis for Process Simulation and Optimization†
- (2009) Yi-dong Lang et al. ENERGY & FUELS
- Quality by design case study: An integrated multivariate approach to drug product and process development
- (2009) Jun Huang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Prediction of tablet properties based on near infrared spectra of raw mixed powders by chemometrics: Scale-up factor of blending and tableting processes
- (2009) Makoto Otsuka et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Effects of rotation rate, mixing angle, and cohesion in two continuous powder mixers—A statistical approach
- (2009) Patricia M. Portillo et al. POWDER TECHNOLOGY
- Parameter estimation in a multidimensional granulation model
- (2009) Andreas Braumann et al. POWDER TECHNOLOGY
- Numerical analysis of density-induced segregation during die filling
- (2009) Y. Guo et al. POWDER TECHNOLOGY
- Knowledge-based method for the validation of complex simulation models
- (2009) Fei-Yan Min et al. SIMULATION MODELLING PRACTICE AND THEORY
- Independent Verification and Validation of an Industrial Simulation Model
- (2009) Stewart Robinson et al. SIMULATION-TRANSACTIONS OF THE SOCIETY FOR MODELING AND SIMULATION INTERNATIONAL
- Predictive Modeling for Pharmaceutical Processes Using Kriging and Response Surface
- (2009) Zhenya Jia et al. Journal of Pharmaceutical Innovation
- A coupled DEM/CFD analysis of the effect of air on powder flow during die filling
- (2008) Y. Guo et al. AICHE JOURNAL
- Continuous mixing of powder mixtures with pharmaceutical process constraints
- (2008) Henri Berthiaux et al. CHEMICAL ENGINEERING AND PROCESSING
- Influence of stirrer type on mixture homogeneity in continuous powder mixing: A model case and a pharmaceutical case
- (2008) K. Marikh et al. CHEMICAL ENGINEERING RESEARCH & DESIGN
- Antisolvent crystallization: Model identification, experimental validation and dynamic simulation
- (2008) S. Mostafa Nowee et al. CHEMICAL ENGINEERING SCIENCE
- Predicting discharge dynamics from a rectangular hopper using the discrete element method (DEM)
- (2008) Anshu Anand et al. CHEMICAL ENGINEERING SCIENCE
- Discrete particle simulation of particulate systems: A review of major applications and findings
- (2008) H.P. Zhu et al. CHEMICAL ENGINEERING SCIENCE
- Bicomponent aggregation with composition-dependent rates and the approach to well-mixed state
- (2008) T. Matsoukas et al. CHEMICAL ENGINEERING SCIENCE
- GUI–HDMR – A software tool for global sensitivity analysis of complex models
- (2008) T. Ziehn et al. ENVIRONMENTAL MODELLING & SOFTWARE
- A global sensitivity study of sulfur chemistry in a premixed methane flame model using HDMR
- (2008) T. Ziehn et al. INTERNATIONAL JOURNAL OF CHEMICAL KINETICS
- The effect of lubrication on density distributions of roller compacted ribbons
- (2008) A.M. Miguélez-Morán et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Process Modeling in the Pharmaceutical Industry using the Discrete Element Method
- (2008) William R. Ketterhagen et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- DEM simulations of die filling during pharmaceutical tabletting
- (2008) Chuan-Yu Wu Particuology
- Discrete-particle investigation of friction effect in filling and unsteady/steady discharge in three-dimensional wedge-shaped hopper
- (2008) Robertas Balevičius et al. POWDER TECHNOLOGY
- Effective Kawakita parameters for binary mixtures
- (2008) Göran Frenning et al. POWDER TECHNOLOGY
- A modeling approach for understanding effects of powder flow properties on tablet weight variability
- (2008) A. Mehrotra et al. POWDER TECHNOLOGY
- Analysis of Manufacturing Costs in Pharmaceutical Companies
- (2008) Prabir Basu et al. Journal of Pharmaceutical Innovation
- Improving Pharmaceutical Product Development and Manufacturing: Impact on Cost of Drug Development and Cost of Goods Sold of Pharmaceuticals
- (2008) Pradeep Suresh et al. Journal of Pharmaceutical Innovation
- Global sensitivity analysis of a 3D street canyon model—Part I: The development of high dimensional model representations
- (2007) T. Ziehn et al. ATMOSPHERIC ENVIRONMENT
- A three-dimensional population balance model of granulation with a mechanistic representation of the nucleation and aggregation phenomena
- (2007) Jonathan M.-H. Poon et al. CHEMICAL ENGINEERING SCIENCE
- Modeling and optimization of a high-pressure ethylene polymerization reactor using gPROMS
- (2007) Mariano Asteasuain et al. COMPUTERS & CHEMICAL ENGINEERING
- Kriging metamodeling in simulation: A review
- (2007) Jack P.C. Kleijnen EUROPEAN JOURNAL OF OPERATIONAL RESEARCH
- Temperature Evolution during Compaction of Pharmaceutical Powders
- (2007) Antonios Zavaliangos et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Characterization of continuous convective powder mixing processes
- (2007) Patricia M. Portillo et al. POWDER TECHNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search