Multiple cells of origin in cholangiocarcinoma underlie biological, epidemiological and clinical heterogeneity

Embryonic Ductal Plate Cells Give Rise to Cholangiocytes, Periportal Hepatocytes, and Adult Liver Progenitor Cells

(2011) Rodolphe Carpentier et al.   GASTROENTEROLOGY

Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors

(2011) Jesper B. Andersen et al.   GASTROENTEROLOGY

Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets

(2011) Vincenzo Cardinale et al.   HEPATOLOGY

Human hepatic stem cell and maturational liver lineage biology

(2011) Rachael Turner et al.   HEPATOLOGY

Risk factors for cholangiocarcinoma

(2011) Gia L. Tyson et al.   HEPATOLOGY

Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages

(2011) Guido Carpino et al.   JOURNAL OF ANATOMY

Functional analysis of microRNAs in human hepatocellular cancer stem cells

(2011) Fanyin Meng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Fighting the bushfire in HCC trials

(2011) Peter Schirmacher et al.   JOURNAL OF HEPATOLOGY

Viral hepatitis is associated with intrahepatic cholangiocarcinoma with cholangiolar differentiation and N-cadherin expression

(2011) Tsan-Hua Yu et al.   MODERN PATHOLOGY

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

Clinical diagnosis and staging of cholangiocarcinoma

(2011) Boris Blechacz et al.   Nature Reviews Gastroenterology & Hepatology

AJCC 7th edition of TNM staging accurately discriminates outcomes of patients with resectable intrahepatic cholangiocarcinoma

(2010) Olivier Farges et al.   CANCER

Oncostatin M Renders Epithelial Cell Adhesion Molecule–Positive Liver Cancer Stem Cells Sensitive to 5-Fluorouracil by Inducing Hepatocytic Differentiation

(2010) Taro Yamashita et al.   CANCER RESEARCH

Epithelial cell adhesion molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor cells in humans

(2010) So-Mi Yoon et al.   HEPATOLOGY

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

A novel approach to biliary tract pathology based on similarities to pancreatic counterparts: Is the biliary tract an incomplete pancreas?

(2010) Yasuni Nakanuma   PATHOLOGY INTERNATIONAL

Intra-hepatic and extra-hepatic cholangiocarcinoma: New insight into epidemiology and risk factors

(2010) Vincenzo Cardinale   World Journal of Gastrointestinal Oncology

New insights into liver stem cells

(2009) E. Gaudio et al.   DIGESTIVE AND LIVER DISEASE

Descriptive epidemiology of cholangiocarcinoma in Italy

(2009) Domenico Alvaro et al.   DIGESTIVE AND LIVER DISEASE

Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9

(2009) Aline Antoniou et al.   GASTROENTEROLOGY

Comparative protein expression profiles of hilar and peripheral hepatic cholangiocarcinomas

(2009) Nathalie Guedj et al.   JOURNAL OF HEPATOLOGY

Embryology of Extra- and Intrahepatic Bile Ducts, the Ductal plate

(2008) T. Roskams et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

The hepatic stem cell niche: Identification by label-retaining cell assay

(2008) Reiichiro Kuwahara et al.   HEPATOLOGY

Clinicopathological study on cholangiolocellular carcinoma suggesting hepatic progenitor cell origin

(2008) Mina Komuta et al.   HEPATOLOGY

Stem cells in liver regeneration, fibrosis and cancer: the good, the bad and the ugly

(2008) MR Alison et al.   JOURNAL OF PATHOLOGY