Article
Gastroenterology & Hepatology
Jun-Hyung Cho, Seong Ran Jeon, So-Young Jin, Suyeon Park
Summary: This study compared the diagnostic performance of standard and M-NBI endoscopy for H. pylori gastritis and precancerous conditions. In 254 patients, M-NBI endoscopy showed slightly higher accuracy for diagnosing H. pylori gastritis and benign conditions compared to standard endoscopy.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Letter
Gastroenterology & Hepatology
Endrit Shahini, Marcello Maida
Summary: There is still controversy surrounding the best surveillance strategies for high-risk patients following H. pylori eradication, indicating the need for further research to establish optimal and cost-effective monitoring strategies. Additionally, studies are required to refine risk stratification for patients with a high likelihood of gastric cancer evolution, taking into account racial, ethnic, immigration factors, and the development of new biomarkers for early diagnosis of malignancy.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Genetics & Heredity
Qi Liu, Danyan Li, Yunkai Dai, Yunzhan Zhang, Shaoyang Lan, Qi Luo, Jintong Ye, Xu Chen, Peiwu Li, Weijing Chen, Ruliu Li, Ling Hu
Summary: This study aimed to investigate the relationship between miR-146a, miR-196a2, miR-149, miR-499, and miR-27a gene single nucleotide polymorphisms (SNPs) and their expressions with pathological changes in gastric mucosa, and to further analyze the interactions between SNPs and Hp. The results showed that miR-196a2 rs11614913 and miR-27a rs895819 may affect the genetic susceptibility to gastric precancerous lesions (GPL) or gastric cancer (GC). The up-regulation of miR-499, miR-196a2, and miR-27a expression caused by Hp infection may be an important mechanism of gastric carcinogenesis.
FRONTIERS IN GENETICS
(2023)
Article
Gastroenterology & Hepatology
Miao Yu, Jing Ma, Xiao-Xia Song, Qiao-Qiao Shao, Xue-Chun Yu, Muhammad Noman Khan, Ya-Bin Qi, Ruo-Bing Hu, Pei-Ru Wei, Wei Xiao, Bai-Ling Jia, Yan-Bo Cheng, Ling-Fei Kong, Chuan-Liang Chen, Song-Ze Ding
Summary: Among children and adolescents in central China, 84.14% were found to have H. pylori infection, with 4.33% of infected patients showing gastric mucosal precancerous lesions, including atrophic gastritis, intestinal metaplasia, and dysplasia. This suggests a critical need for further investigation and intervention in this population group.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Letter
Gastroenterology & Hepatology
Saroj Kanta Sahu, Ayaskanta Singh
Summary: This study compared standard endoscopy and NBI-M in the diagnosis of H. pylori infections, atrophic gastritis, and intestinal metaplasia. Although NBI-M had better sensitivity, the diagnostic accuracy was similar between the modalities. Future studies may help guide endoscopists in choosing the most effective and cost-effective diagnostic modality for difficult cases of H. pylori-related gastritis and precancerous conditions.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Biochemistry & Molecular Biology
Rina Fujiwara-Tani, Tadataka Takagi, Shiori Mori, Shingo Kishi, Yukiko Nishiguchi, Takamitsu Sasaki, Masayuki Ikeda, Kenta Nagai, Ujjal Kumar Bhawal, Hitoshi Ohmori, Kiyomu Fujii, Hiroki Kuniyasu
Summary: Gastric cancers are closely associated with Helicobacter pylori infection and intestinal metaplasia. Telomere reduction and dysplastic metaplasia (DM) were found to be characteristics of high-risk intestinal metaplasia. A 10-year follow-up study revealed that high-grade DM cases have a high risk of progressing to gastric cancer, suggesting the importance of identifying and treating high-grade DM in H. pylori-positive patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Editorial Material
Microbiology
Agustina Taglialegna
Summary: In this study, Sharafutdinov et al. report the identification of a single nucleotide polymorphism in the gene encoding the HtrA protease of Helicobacter pylori that is linked to gastric cancer.
NATURE REVIEWS MICROBIOLOGY
(2023)
Article
Oncology
Abbas Esmaeilzadeh, Ladan Goshayeshi, Robert Bergquist, Lida Jarahi, Alireza Khooei, Alireza Fazeli, Hooman Mosannen Mozaffari, Ali Bahari, Mohammad Bagher Oghazian, Benyamin Hoseini
Summary: Early detection and appropriate treatment of precancerous, mucosal changes can reduce the prevalence of life-threatening gastric cancer. This study found a high prevalence of H. pylori infection and precancerous conditions in dyspeptic patients, especially those over 40 years old with opium addiction, suggesting the need for gastric endoscopy and biopsy even in patients with normal-appearing mucosa.
Article
Multidisciplinary Sciences
Tomohiko Yasuda, Hyun Seok Lee, Su Youn Nam, Hiroto Katoh, Yuko Ishibashi, Somay Yamagata Murayama, Hidenori Matsui, Hiroki Masuda, Emiko Rimbara, Nobuyuki Sakurazawa, Hideyuki Suzuki, Hiroshi Yoshida, Yasuyuki Seto, Shumpei Ishikawa, Seong Woo Jeon, Masahiko Nakamura, Sachiyo Nomura
Summary: Genetic analysis and culturing techniques for gastric non-Helicobacter pylori Helicobacter (NHPH) are advancing, with NHPH reported to accompany certain gastric conditions. A study on Korean gastric cancer patients found a low percentage positive for NHPH, suggesting it may play a role in gastric cancer development, albeit with lower pathogenicity compared to H. pylori.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Analytical
Shan-Wen Hu, Xiao-Rong Zhang, Wan-Xin Li, Lan-Lan Chen, Wei Zhao, Jing-Juan Xu, Wei-Min Ye
Summary: This study designed an X-shaped DNA probe for specific hybridization with certain genotype DNA and developed a competitive reaction to amplify the thermodynamic difference between wild-type DNA and SNVs in H. pylori. Multiple SNVs were successfully identified and a paper strip for visual, fast screening of SNVs was fabricated. The approach was validated using clinical samples and demonstrated the potential for the prevention and cure of H. pylori infections through point-of-care testing diagnosis on saliva samples.
Article
Medicine, General & Internal
Yoshiaki Usui, Yukari Taniyama, Mikiko Endo, Yuriko N. Koyanagi, Yumiko Kasugai, Isao Oze, Hidemi Ito, Issei Imoto, Tsutomu Tanaka, Masahiro Tajika, Yasumasa Niwa, Yusuke Iwasaki, Tomomi Aoi, Nozomi Hakozaki, Sadaaki Takata, Kunihiko Suzuki, Chikashi Terao, Masanori Hatakeyama, Makoto Hirata, Kokichi Sugano, Teruhiko Yoshida, Yoichiro Kamatani, Hidewaki Nakagawa, Koichi Matsuda, Yoshinori Murakami, Amanda B. Spurdle, Keitaro Matsuo, Yukihide Momozawa
Summary: This study reveals that certain genetic variants associated with Helicobacter pylori infection can increase the risk of gastric cancer. Individuals carrying these genetic variants and infected with H. pylori have an even higher risk of developing gastric cancer.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Silvia Salvatori, Irene Marafini, Federica Laudisi, Giovanni Monteleone, Carmine Stolfi
Summary: H. pylori infection contributes to the onset and development of gastric cancer through the mechanisms of chronic inflammation and DNA damage to gastric epithelial cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Gastroenterology & Hepatology
Fangyuan Zhu, Xiaoze Zhang, Ping Li, Yaodong Zhu
Summary: This meta-analysis evaluated the effect of Helicobacter pylori (Hp) eradication on gastric precancerous lesions. The results showed that Hp eradication could significantly prevent the progression and reverse the gastric precancerous lesions, especially in terms of improving intestinal metaplasia and chronic atrophic gastritis. However, there was no advantage of Hp eradication compared to placebo or no treatment in preventing dysplasia progression and improving dysplasia.
Article
Biochemical Research Methods
Lusheng Song, Minkyo Song, Charles S. Rabkin, Stacy Williams, Yunro Chung, Jennifer Van Duine, Linda M. Liao, Kailash Karthikeyan, Weimin Gao, Jin G. Park, Yanyang Tang, Jolanta Lissowska, Ji Qiu, Joshua LaBaer, M. Constanza Camargo
Summary: This study evaluated humoral responses to a nearly complete H. pylori immunoproteome among GC cases and controls, finding higher prevalence of certain antibodies in controls and lower seroprevalence in GC cases, suggesting immune protection and potential changes in specific proteins.
JOURNAL OF PROTEOME RESEARCH
(2021)
Article
Infectious Diseases
Mohamed Reda Jouimyi, Ghizlane Bounder, Imane Essaidi, Hasna Boura, Wafaa Badre, Hakima Benomar, Khalid Zerouali, Halima Lebrazi, Anass Kettani, Fatima Maachi
Summary: The study demonstrates that the genetic diversity of the Helicobacter pylori vacA gene is associated with the risk of atrophic gastritis and intestinal metaplasia. Genotypes s1, m1, and i1 of vacA are linked to a higher risk of intestinal metaplasia, while genotype d1 increases the risk of atrophic gastritis and intestinal metaplasia. The results highlight the potential of vacA d region genotyping as a reliable marker for identifying virulent strains with a high risk of developing precancerous lesions.
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
(2021)
Article
Peripheral Vascular Disease
Shohei Chatani, Ryota Tsukii, Kyohei Nagasawa, Takaaki Hasegawa, Shinichi Murata, Mina Kato, Hidekazu Yamaura, Hiroaki Onaya, Keitaro Matsuo, Yoshiyuki Watanabe, Yoshitaka Inaba
Summary: This study investigated the difficulty in removing totally implantable venous access devices (TIVADs) and identified associated risk factors. Interventional radiology (IR) approaches for difficult removal were also explored. The results showed that indwelling duration and subcutaneous leakage of fluid were significant risk factors for difficult removal. IR techniques were found to be minimally invasive and useful in some cases.
JOURNAL OF VASCULAR ACCESS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Neerav Goyal, Max Hennessy, Erik Lehman, Wenxue Lin, Antonio Agudo, Wolfgang Ahrens, Stefania Boccia, Paul Brennan, Hermann Brenner, Gabriella Cadoni, Cristina Canova, Chu Chen, David Conway, Maria Paula Curado, Luigino Dal Maso, Alexander W. Daudt, Valeria Edefonti, Eleonora Fabianova, Leticia Fernandez, Silvia Franceschi, Werner Garavello, Maura Gillison, Richard B. Hayes, Claire Healy, Rolando Herrero, Ivana Holcatova, Jossy L. Kanda, Karl Kelsey, Bo T. Hansen, Rosalina Koifman, Pagona Lagiou, Carlo La Vecchia, Fabio Levi, Guojun Li, Jolanta Lissowska, Rossana Mendoza Lopez, Daniele Luce, Gary Macfarlane, Dana Mates, Keitaro Matsuo, Michael McClean, Ana Menezes, Gwenn Menvielle, Hal Morgenstern, Kirsten Moysich, Eva Negri, Andrew F. Olshan, Tamas Pandics, Jerry Polesel, Mark Purdue, Loredana Radoi, Heribert Ramroth, Lorenzo Richiardi, Stimson Schantz, Stephen M. Schwartz, Diego Serraino, Oxana Shangina, Elaine Smith, Erich M. Sturgis, Beata Swiatkowska, Peter Thomson, Thomas L. Vaughan, Marta Vilensky, Deborah M. Winn, Victor Wunsch-Filho, Guo-Pei Yu, Jose P. Zevallos, Zuo-Feng Zhang, Tongzhang Zheng, Ariana Znaor, Paolo Boffetta, Mia Hashibe, Yuan-Chin A. Lee, Joshua E. Muscat
Summary: This study analyzed the relationship between cigarette smoking, alcohol consumption, and head and neck cancer risk factors in less developed and more developed countries. The results showed that the duration of smoking and alcohol consumption had different effects on the risk of specific cancer sites depending on the country's level of development. These findings suggest that the degree of industrialization and economic development affects the relationship between smoking, alcohol, and head and neck cancer.
Article
Ophthalmology
Akiko Hanyuda, Atsushi Goto, Masahiro Nakatochi, Yoichi Sutoh, Akira Narita, Shiori Nakano, Ryoko Katagiri, Kenji Wakai, Naoyuki Takashima, Teruhide Koyama, Kokichi Arisawa, Issei Imoto, Yukihide Momozawa, Kozo Tanno, Atsushi Shimizu, Atsushi Hozawa, Kengo Kinoshita, Taiki Yamaji, Norie Sawada, Masao Iwagami, Kenya Yuki, Kazuo Tsubota, Kazuno Negishi, Keitaro Matsuo, Masayuki Yamamoto, Makoto Sasaki, Shoichiro Tsugane, Motoki Iwasaki
Summary: This study conducted a Mendelian randomization analysis to assess the causal association between genetically predicted glycemic traits and the risk of primary open-angle glaucoma (POAG). The results did not provide strong evidence to support the association between genetically predicted glycemic traits and POAG in the Japanese population.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Takaaki Hasegawa, Haruyuki Takaki, Hiroshi Kodama, Keitaro Matsuo, Takashi Yamanaka, Atsuhiro Nakatsuka, Motoshi Takao, Hideo Gobara, Sadao Hayashi, Yoshitaka Inaba, Koichiro Yamakado
Summary: The purpose of this study was to explore the impact of ablative margin depicted by CT immediately after RF ablation on reducing LTP for CRC lung metastases. A retrospective study was conducted on 70 patients who underwent RF ablation for CRC lung metastases. The results indicated that an ablative margin of at least 2 mm is important to reduce LTP after RF ablation for CRC lung metastases.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Letter
Rheumatology
Yu Toyoda, Masahiro Nakatochi, Akiyoshi Nakayama, Yusuke Kawamura, Hirofumi Nakaoka, Kenji Wakai, Keitaro Matsuo, Hirotaka Matsuo
Article
Rheumatology
Ai Yaku, Yuki Ishikawa, Takeshi Iwasaki, Ryosuke Hiwa, Keitaro Matsuo, Hiroh Saji, Kimiko Yurugi, Yasuo Miura, Moritoshi Furu, Hiromu Ito, Takao Fujii, Taira Maekawa, Motomu Hashimoto, Koichiro Ohmura, Tsuneyo Mimori, Chikashi Terao
Summary: Objective HLA-DRB1 alleles, particularly the shared epitope (SE) alleles, are strongly associated with RA. Different genetic structures underlie the production of the various autoantibodies in RA. However, the genetic architecture underlying IgG-RF, which is associated with rheumatoid vasculitis, is not well understood.
Article
Public, Environmental & Occupational Health
Mako Nagayoshi, Asahi Hishida, Tomonori Shimizu, Yasufumi Kato, Yoko Kubo, Rieko Okada, Takashi Tamura, Jun Otonari, Hiroaki Ikezaki, Megumi Hara, Yuichiro Nishida, Isao Oze, Yuriko N. Koyanagi, Yohko Nakamura, Miho Kusakabe, Rie Ibusuki, Keiichi Shibuya, Sadao Suzuki, Takeshi Nishiyama, Teruhide Koyama, Etsuko Ozaki, Kiyonori Kuriki, Naoyuki Takashima, Yasuyuki Nakamura, Sakurako Katsuura-Kamanos, Kokichi Arisawa, Masahiro Nakatochi, Yukihide Momozawa, Kenji Takeuchi, Kenji Wakai, J-MICC Study group
Summary: This study found that higher BMI in the Japanese population is causally associated with various cardiometabolic traits including high blood pressure, triglycerides, uric acid, low high-density-lipoprotein cholesterol, and eGFR. However, there was no significant association between genetic risk scores for BMI and individual-level cardiometabolic traits.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Oncology
Tomoharu Mori, Yusuke Okamoto, Anfeng Mu, Yoshimi Ide, Akiyo Yoshimura, Noriko Senda, Yukiko Inagaki-Kawata, Masahiro Kawashima, Hiroyuki Kitao, Eriko Tokunaga, Yasuo Miyoshi, Shozo Ohsumi, Koichiro Tsugawa, Tomohiko Ohta, Toyomasa Katagiri, Shigeru Ohtsuru, Kaoru Koike, Seishi Ogawa, Masakazu Toi, Hiroji Iwata, Seigo Nakamura, Keitaro Matsuo, Minoru Takata
Summary: The ALDH2 enzyme's ability to break down aldehydes is impaired by a specific gene polymorphism, leading to alcohol flushing and an increased risk of esophageal cancer in East Asians. Recent studies suggest that this gene variant may result in higher levels of DNA damage caused by naturally occurring aldehydes. However, in breast epithelial cells, this loss of function does not appear to have an impact on the initiation and development of cancer.
Article
Endocrinology & Metabolism
Takuya Sakashita, Yasuyuki Nakamura, Yoichi Sutoh, Atsushi Shimizu, Tsuyoshi Hachiya, Yayoi Otsuka-Yamasaki, Naoyuki Takashima, Aya Kadota, Katsuyuki Miura, Yoshikuni Kita, Hiroaki Ikezaki, Jun Otonari, Keitaro Tanaka, Chisato Shimanoe, Teruhide Koyama, Isao Watanabe, Sadao Suzuki, Hiroko Nakagawa-Senda, Asahi Hishida, Takashi Tamura, Yasufumi Kato, Rieko Okada, Kiyonori Kuriki, Sakurako Katsuura-Kamano, Takeshi Watanabe, Shiroh Tanoue, Chihaya Koriyama, Isao Oze, Yuriko N. Koyanagi, Yohko Nakamura, Miho Kusakabe, Masahiro Nakatochi, Yukihide Momozawa, Kenji Wakai, Keitaro Matsuo
Summary: This study investigates the association between HbA1c and blood glucose levels and their corresponding genetic loci in a non-diabetic Japanese population. The study identifies KCNQ1 and TMC6 loci as being associated with HbA1c levels, but no replication is found for the loci associated with blood glucose levels. Furthermore, the variant rs2299620 in KCNQ1 shows heterogeneity in its effect on HbA1c levels based on BMI grouping.
DIABETOLOGY INTERNATIONAL
(2023)
Article
Oncology
Yuriko Koyanagi, Keitaro Matsuo, Hidemi Ito, Chaochen Wang, Akiko Tamakoshi, Yumi Sugawara, Ichiro Tsuji, Ayami Ono, Shoichiro Tsugane, Norie Sawada, Keiko Wada, Chisato Nagata, Taro Takeuchi, Tetsuhisa Kitamura, Mai Utada, Ritsu Sakata, Tetsuya Mizoue, Sarah Krull Abe, Manami Inoue
Summary: The effect of body mass index (BMI) on esophageal and gastric carcinogenesis varies depending on subtype or subsite. In this study, a pooled analysis of 10 population-based cohort studies in Japan, we observed an inverse association between BMI and esophageal squamous cell carcinoma, but a positive association with gastric cardia cancer. Additionally, a positive association was found for overweight or obese individuals with esophageal adenocarcinoma and gastric cardia cancer. The study highlights the subtype- or subsite-specific impact of BMI on upper gastrointestinal cancer in the Japanese population.
Article
Public, Environmental & Occupational Health
Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, Ippei Shimoshikiryo, Daisaku Nishimoto, Keiichi Shimatani, Toshiro Takezaki, Hiroaki Ikezaki, Masayuki Murata, Megumi Hara, Yuichiro Nishida, Takashi Tamura, Asahi Hishida, Mako Nagayoshi, Rieko Okada, Keitaro Matsuo, Hidemi Ito, Haruo Mikami, Yohko Nakamura, Takahiro Otani, Sadao Suzuki, Teruhide Koyama, Etsuko Ozaki, Kiyonori Kuriki, Naoyuki Takashima, Naoko Miyagawa, Kokichi Arisawa, Sakurako Katsuura-Kamano, Yukihide Momozawa, Michiaki Kubo, Kenji Takeuchi, Kenji Wakai
Summary: The study evaluated the population-based impact of smoking, drinking, and genetic factors on low HDL-C levels using data from the J-MICC Study. The findings showed that smoking, drinking, and certain genetic variants were associated with HDL-C levels, but there was no significant gene-environment interaction. The population-based impact of the genetic factor CETP rs3764261 was higher than that of smoking and lower than that of drinking.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Mako Nagayoshi, Kenji Takeuchi, Yudai Tamada, Yasufumi Kato, Yoko Kubo, Rieko Okada, Takashi Tamura, Asahi Hishida, Jun Otonari, Hiroaki Ikezaki, Yuichiro Nishida, Chisato Shimanoe, Yuriko N. Koyanagi, Keitaro Matsuo, Haruo Mikami, Miho Kusakabe, Daisaku Nishimoto, Keiichi Shibuya, Sadao Suzuki, Takeshi Nishiyama, Etsuko Ozaki, Isao Watanabe, Kiyonori Kuriki, Naoyuki Takashima, Aya Kadota, Kokichi Arisawa, Sakurako Katsuura-Kamano, Kenji Wakai
Summary: In Japanese adults, stress-coping strategies are related to all-cause mortality. Three coping strategies (emotional expression, emotional support-seeking, and disengagement) were associated with lower mortality in women. Emotional expression, problem-solving, and positive reappraisal were associated with lower mortality in men, but the relationship depended on the follow-up period. There was evidence of sex differences in the relationship between emotional support-seeking and all-cause mortality.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Nutrition & Dietetics
Takashi Tamura, Kenji Wakai, Yasufumi Kato, Yudai Tamada, Yoko Kubo, Rieko Okada, Mako Nagayoshi, Asahi Hishida, Nahomi Imaeda, Chiho Goto, Hiroaki Ikezaki, Jun Otonari, Megumi Hara, Keitaro Tanaka, Yohko Nakamura, Miho Kusakabe, Rie Ibusuki, Chihaya Koriyama, Isao Oze, Hidemi Ito, Sadao Suzuki, Hiroko Nakagawa-Senda, Etsuko Ozaki, Daisuke Matsui, Kiyonori Kuriki, Keiko Kondo, Naoyuki Takashima, Takeshi Watanabe, Sakurako Katsuura-Kamano, Keitaro Matsuo
Summary: This study aimed to examine the associations between carbohydrate and fat intakes and mortality risk. The results showed that low carbohydrate intake was associated with increased all-cause mortality risk in men, while high carbohydrate intake was associated with increased all-cause mortality risk in women. Additionally, high fat intake was potentially associated with lower mortality risk in women with relatively high carbohydrate intake.
JOURNAL OF NUTRITION
(2023)
Article
Oncology
Yoshiaki Usui, Hidemi Ito, Kota Katanoda, Tomohiro Matsuda, Yoshinobu Maeda, Keitaro Matsuo
Summary: The introduction of rituximab has led to a decline in mortality rates of non-Hodgkin lymphoma in both Japan and the United States, despite an increase in incidence. However, the trends in mortality rates have differed between the two countries, with the mortality rate declining continuously in the United States but stopping in Japan.
Article
Public, Environmental & Occupational Health
Daisaku Nishimoto, Rie Ibusuki, Ippei Shimoshikiryo, Kenichi Shibuya, Shiroh Tanoue, Chihaya Koriyama, Toshiro Takezaki, Isao Oze, Hidemi Ito, Asahi Hishida, Takashi Tamura, Yasufumi Kato, Yudai Tamada, Yuichiro Nishida, Chisato Shimanoe, Sadao Suzuki, Takeshi Nishiyama, Etsuko Ozaki, Satomi Tomida, Kiyonori Kuriki, Naoko Miyagawa, Keiko Kondo, Kokichi Arisawa, Takeshi Watanabe, Hiroaki Ikezaki, Jun Otonari, Kenji Wakai, Keitaro Matsuo
Summary: This Japanese cohort study examined the association between awareness of limiting food intake and all-cause mortality risk. The results showed that women with awareness of limiting fat intake had a significantly lower mortality risk, while awareness of limiting energy or sweets intake was not related to mortality risk reduction.
JOURNAL OF EPIDEMIOLOGY
(2023)
