4.4 Article

Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis

Journal

OPEN FORUM INFECTIOUS DISEASES
Volume 1, Issue 2, Pages -

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofu046

Keywords

bacteremia; ceftaroline fosamil; MRSA; salvage

Funding

  1. National Institutes of Health [T-32, AI007291]

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No clinical trials have investigated the use of ceftaroline fosamil for salvage therapy of methicillin-resistant Staphylococcus aureus bacteremia and endocarditis. We report data on 29 patients who received ceftaroline +/- another antimicrobial for this indication. Ninety percent of patients had microbiologic cure and 31% had treatment success with a median follow-up of 6 months.

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