Article
Urology & Nephrology
Chi D. Chu, Neil R. Powe, Deidra C. Crews, Delphine S. Tuot
Summary: This study compares the time to kidney failure with replacement therapy among Black, Hispanic, and White patients, and assesses the impact of incorporating race into the estimation of glomerular filtration rate on waitlist eligibility and time to kidney failure. The results show that Black and Hispanic patients have less opportunity to be placed on the transplant waitlist compared to White patients. For many Black patients, estimating the filtration rate as if their race were non-Black could allow for earlier waitlisting.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2022)
Article
Transplantation
Aarti Mathur, JiYoon B. Ahn, Whitney Sutton, Nadia M. Chu, Alden L. Gross, Dorry L. Segev, Mara McAdams-DeMarco
Summary: Receiving treatment for secondary hyperparathyroidism (SHPT) was associated with a lower risk of incident dementia among older patients with end-stage renal disease (ESRD). The beneficial effect of SHPT treatment differed by sex and race, with females and those of Asian or Black race experiencing the greatest reduction in dementia risk.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Endocrinology & Metabolism
Chieh-Li Yen, Pei-Chun Fan, Ming-Shyan Lin, Cheng-Chia Lee, Kun-Hua Tu, Chao-Yu Chen, Ching-Chung Hsiao, Hsiang-Hao Hsu, Ya-Chung Tian, Chih-Hsiang Chang
Summary: This study found that among advanced CKD patients, the use of fenofibrate and statins can reduce the risk of cardiovascular death, while fenofibrate can also reduce the incidence of permanent dialysis.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Urology & Nephrology
Julien Prouvot, Emilie Pambrun, Valery Antoine, Cecile Couchoud, Cecile Vigneau, Sophie Roche, Maud Francois, Christophe Mariat, Daniela Babici, Camelia Prelipcean, Olivier Moranne, Pspa Investigators
Summary: The study evaluated existing prognostic scores for predicting death in elderly CKD patients before initiating dialysis, and found that the available scores showed low performance in a French multicentre cohort, indicating the need to upgrade or develop new scores for this population.
JOURNAL OF NEPHROLOGY
(2022)
Article
Urology & Nephrology
Julien Prouvot, Emilie Pambrun, Cecile Couchoud, Cecile Vigneau, Sophie Roche, Vincent Allot, Jerome Potier, Maud Francois, Daniela Babici, Camelia Prelipcean, Olivier Moranne
Summary: Evaluating existing risk model scores predicting end stage renal disease (ESRD) in a cohort of octogenarian patients with advanced chronic kidney disease (CKD) showed poor performance, highlighting the necessity for developing new tools for this population.
JOURNAL OF NEPHROLOGY
(2021)
Article
Transplantation
Victor Fages, Natalia Alencar de Pinho, Aghiles Hamroun, Celine Lange, Christian Combe, Denis Fouque, Luc Frimat, Christian Jacquelinet, Maurice Laville, Carole Ayav, Sophie Liabeuf, Roberto Pecoits-Filho, Ziad A. Massy, Julie Boucquemont, Benedicte Stengel
Summary: This study identifies important patient- and provider-level factors that are associated with urgent-start dialysis, highlighting the need to address these factors to reduce the burden of urgent dialysis initiation.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Urology & Nephrology
Chi D. Chu, Charles E. Mcculloch, Raymond K. Hsu, Neil R. Powe, Brian Bieber, Bruce M. Robinson, Rupesh Raina, Roberto Pecoits-Filho, Delphine S. Tuot
Summary: The Kidney Failure Risk Equation (KFRE) can predict the risk of kidney failure for patients with chronic kidney disease (CKD), and translating this prediction into time can help inform decision making for patients approaching kidney failure.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2023)
Article
Cardiac & Cardiovascular Systems
Charles A. Herzog, Mengistu A. Simegn, Yifan Xu, Salvatore P. Costa, Roy O. Mathew, Mohammad C. El-Hajjar, Sanjeev Gulati, Rafael A. Maldonado, Eric Daugas, Magdelena Madero, Jerome L. Fleg, Rebecca Anthopolos, Gregg W. Stone, Mandeep S. Sidhu, David J. Maron, Judith S. Hochman, Sripal Bangalore
Summary: In the ISCHEMIA-CKD study, an invasive strategy did not show improved outcomes compared to conservative management in kidney transplant candidates. These findings do not recommend routine coronary angiography or revascularization for patients with advanced CKD and chronic coronary syndromes listed for transplant.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Urology & Nephrology
Timothy O. Olanrewaju, Charlotte Osafo, Yemi R. Raji, Manmak Mamven, Samuel Ajayi, Titilayo O. Ilori, Fatiu A. Arogundade, Ifeoma I. Ulasi, Rasheed Gbadegesin, Rulan S. Parekh, Bamidele Tayo, Adebowale A. Adeyemo, Olanrewaju T. Adedoyin, Adindu A. Chijioke, Clemen Bewaji, Diederick E. Grobbee, Peter J. Blankestijin, Kerstin Klipstein-Grobusch, Babatunde L. Salako, Dwomoa Adu, Akinlolu O. Ojo
Summary: This study investigated the prevalence of cardiovascular risk factors in CKD patients in Africa and found that hypertension, elevated cholesterol, and low BMI were independently associated with CKD.
KIDNEY INTERNATIONAL REPORTS
(2023)
Article
Urology & Nephrology
Sebastiaan Lambooy, Rathika Krishnasamy, Andrea Pollock, Gerald Hilder, Nicholas A. Gray
Summary: This study evaluated the feasibility and clinical outcomes of telehealth videoconferencing for kidney transplant recipients and chronic kidney disease patients. The research found that TVC uptake was high in the first year but significantly reduced in the second year. There were no significant differences in creatinine and blood pressure between the TVC group and the control group, with high patient satisfaction reported in both groups.
KIDNEY INTERNATIONAL REPORTS
(2021)
Article
Cell Biology
Xiao Lin, Ting Zhu, Feng Xu, Jia-Yu Zhong, Fuxingzi Li, Su-Kang Shan, Feng Wu, Bei Guo, Ming-Hui Zheng, Yi Wang, Qiu-Shuang Xu, Xiao-Bo Liao, Hong-Yu Lu, Xu-Biao Xie, Ling-Qing Yuan
Summary: This study found that plasma exosomes from ESRD patients significantly promoted vascular smooth muscle cells calcification, while renal transplantation partially attenuated this procalcification effect. Fetuin-A and MGP were decreased, but Annexin-A2 was increased in ESRD-Ex, and renal transplantation could increase the level of Fetuin-A rather than MGP. The levels of Fetuin-A and MGP in plasma exosomes were negatively while the levels of Annexin-A2 in plasma exosomes were positively correlated to coronary artery calcification scores (CACS).
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Boqiang Lin, David Iheke Okorie
Summary: This article explores the drivers of agricultural greenhouse gas emissions in Nigeria and potential pathways for emission reduction. The study reveals that agricultural greenhouse gas emission intensity and per capita output are the leading factors affecting the total emission level in Nigeria's agricultural sector.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Urology & Nephrology
Marie Dirix, Ester Philipse, Rowena Vleut, Vera Hartman, Bart Bracke, Thierry Chapelle, Geert Roeyen, Dirk Ysebaert, Gerda Van Beeumen, Erik Snelders, Annick Massart, Katrien Leyssens, Marie M. Couttenye, Daniel Abramowicz, Rachel Hellemans
Summary: The study emphasizes the importance of starting the transplant workup in a timely fashion for kidney transplant patients. Only 43% of patients initiated the workup before starting dialysis, and the completion time for the workup was unexpectedly long. The number of hospitalization days and language barriers were found to significantly impact the timing and duration of the transplant workup.
CLINICAL KIDNEY JOURNAL
(2022)
Article
Transplantation
Luca De Nicola, Raffaele Serra, Michele Provenzano, Roberto Minutolo, Ashour Michael, Nicola Ielapi, Stefano Federico, Rosa Carrano, Vincenzo Bellizzi, Carlo Garofalo, Carmela Iodice, Silvio Borrelli, Giuseppe Grandaliano, Giovanni Stallone, Loreto Gesualdo, Paolo Chiodini, Michele Andreucci
Summary: This study compared the risk and determinants of end-stage kidney disease (ESKD) between kidney transplant recipients (KTR) and patients with native chronic kidney disease (CKD). The results showed that the risk of ESKD in KTR was lower in the first 5 years and higher later on compared to CKD patients. Traditional determinants of ESKD accounted for one-third of the variability of time-to-graft failure.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Urology & Nephrology
Jia Zhang, Chris H. L. Thio, Ron T. Gansevoort, Harold Snieder
Summary: This study showed that a positive family history was strongly associated with increased risk of CKD. Genetic factors play an important role in the risk of kidney disease. There is moderate to high heritability of kidney traits and related biomarkers.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2021)